Alfred Millett-Sikking Email and Phone Number
Alfred Millett-Sikking work email
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Alfred Millett-Sikking personal email
I’m a hybrid physicist and engineer who is fascinated by the notion of optimal designs. I’ve spent my career assembling experience in applied physics, optics, mechanics, electronics, programming and microscopy. I seek to improve technologies, and invent new ones, with element and system level innovations.
Calico Life Sciences
View- Website:
- calicolabs.com
- Employees:
- 214
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Staff EngineerCalico Life Sciences Jul 2024 - Present
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Senior EngineerCalico Life Sciences Aug 2021 - Jun 2024I invented a novel technique to image 3D samples of any refractive index at high resolution using an immersion objective of any type[Millett-Sikking 2023]. This new 'any immersion remote refocus' (AIRR) microscopy method is particularly powerful when using a high numerical aperture air objective to image into 3D biological samples[Millett-Sikking 2022]. I then applied the AIRR technology to design and build a state of the art, large field of view, single-objective light-sheet (SOLS) microscope at Calico, including real-time multi-angle projections[Chang 2021]. I also built a fast and flexible widefield microscope and continued to collaborate with SOLS builders (Snoutclub) on many projects[Sommernes 2024, Bodén 2024].
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Scientist IiCalico Life Sciences Aug 2020 - Jul 2021San Francisco Bay AreaThe main drive of this period was to produce a user level SOLS microscope for Calico. In practice this meant developing device adaptors, instrument control and data processing software, and well as build and alignment procedures to get good PSF data. This naturally led to training users and early biological applications [Okreglak 2023].
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ScientistCalico Life Sciences Jan 2018 - Aug 2020San Francisco Bay AreaInitially I developed a series of custom ASI microscopes for 'The Yeast Lifespan' project at Calico[Thayer 2022]. This was followed by a major breakthrough when I designed a new kind of objective lens, the 'AMS-AGY' objective (a.k.a 'Snouty'), that revolutionized light-sheet microscopy [Millett-Sikking 2019, Riolka 2019, Millett-Sikking 2020]. The new "single-objective light-sheet" (SOLS) architecture is inherently fast, gentle, 3D and compatible with standard samples, making it a versatile and valuable technology [Sapoznik 2020, Millett-Sikking 2020]. This platform was then extended to larger fields of view[ Yang 2022, Chen 2022].
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Senior Research AssociateCalico Life Sciences Aug 2015 - Dec 2017San Francisco Bay AreaAs a founding member of the York lab, I developed the original microscopy core and technology labs at Calico. In particular I designed and built a novel fast focusing module for a Leica microscope using Nikon remote refocus (RR) optics [Millett-Sikking 2018].
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Research And Development EngineerVisitech International Ltd Feb 2013 - Jun 2015Sunderland, United KingdomLead engineer in the development of multipoint laser scanning confocal microscopes (VT-Infinity). Including the full opto-mechanical design of a new super-resolution imaging system [York 2013] that was taken from concept stage to final product (VT-iSIM).
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Postgraduate Research AssociateDurham University 2011 - 2012Durham, United KingdomThe first year of a PhD with the Quantum Light and Matter (QLM) group. I built and tested various intricate optical systems and completed the postgraduate courses. -
Postgraduate ResearcherUniversity Of Bristol 2008 - 2009Bristol, United KingdomResearch into small scale renewable energy technology in the Electrical Energy Management Group (EEMG), including the design and build of electronic devices. -
Project Controls EngineerBechtel Corporation 2007 - 2008London, United KingdomWorked in the procurement department of Saudi Aramco’s Khursaniyah Gas Plant. Handled the purchase and cancellation of more than 5million USD of materials.
Alfred Millett-Sikking Skills
Alfred Millett-Sikking Education Details
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1St Class Honours And D. A. Wright Prize For Best Research Project
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A, A, B, B, B. -
Malton School
Frequently Asked Questions about Alfred Millett-Sikking
What company does Alfred Millett-Sikking work for?
Alfred Millett-Sikking works for Calico Life Sciences
What is Alfred Millett-Sikking's role at the current company?
Alfred Millett-Sikking's current role is Staff Engineer at Calico Life Sciences.
What is Alfred Millett-Sikking's email address?
Alfred Millett-Sikking's email address is am****@****abs.com
What schools did Alfred Millett-Sikking attend?
Alfred Millett-Sikking attended Durham University, York College, York Uk, Malton School.
What skills is Alfred Millett-Sikking known for?
Alfred Millett-Sikking has skills like R&d, Optics, Physics, Matlab, Experimental Physics, Microscopy, Confocal Microscopy, Latex, Laser Physics, Simulations, Algorithms, Project Engineering.
Who are Alfred Millett-Sikking's colleagues?
Alfred Millett-Sikking's colleagues are John Wang, Ivan Novak, Bryan King, Xiang Zhu, Angelica Gonzalez, Jack Houston, Tim Hoffman.
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