Ana Ruiz-Saenz

Ana Ruiz-Saenz Email and Phone Number

Principal Investigator at CIC bioGUNE @ CIC bioGUNE
derio, basque country, spain
Ana Ruiz-Saenz's Location
Derio, Basque Country, Spain, Spain
Ana Ruiz-Saenz's Contact Details

Ana Ruiz-Saenz work email

Ana Ruiz-Saenz personal email

n/a
About Ana Ruiz-Saenz

Assistant Professor at Erasmus Medical Center in The Netherlands, working on elucidating the molecular mechanisms of cancer progression, aiming to turn laboratory discoveries into personalized cancer therapies. I am interested in characterizing the mode of function of HER2, and its partner HER3, in the pathological state of HER2 overexpression, in order to define a mechanistic basis for the development of novel therapeutic agents for the treatment of HER2-amplified cancers.As a postdoc fellow at the University of California San Francisco, I revealed new paradigms in cell signaling and cancer resistance in breast and colorectal cancers(published in Nature Cancer, Cancer Research and Oncogene, among others). In 2019, I established my own research group at Erasmus MC supported by the Marie Skłodowska-Curie Actions Programme and the Dutch Research Council. Our aim is to uncover the impact of aberrant tumor glycosylation on the efficacy of targeted therapies integrating clinical data, co-culture 3D immune-cancer spheroids and high-content live-imaging. Specifically, my lab is currently deciphering the impact of altered glycosylation on the response to HER2-targeting agents in breast cancer, including a recent and promising therapeutic agent developed by AstraZeneca.My experience in the US and Europe has enabled me to establish fruitful collaborations with international experts and the pharmaceutical industry. I have also actively participated in numerous conferences and outreach activities, including fundraising events and science communication events. And I am also a lecturer of the Molecular Medicine Master program at Erasmus Medical Center.

Ana Ruiz-Saenz's Current Company Details
CIC bioGUNE

Cic Biogune

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Principal Investigator at CIC bioGUNE
derio, basque country, spain
Website:
cicbiogune.es
Employees:
191
Ana Ruiz-Saenz Work Experience Details
  • Cic Biogune
    Principal Investigator
    Cic Biogune Dec 2023 - Present
    Bilbao-Bilbo, Basque Country, Spain
  • Erasmus Mc
    Assistant Professor
    Erasmus Mc 2021 - Present
    Rotterdam, South Holland, Netherlands
  • Erasmus Mc
    Principal Investigator
    Erasmus Mc Jul 2019 - Dec 2023
    Rotterdam Area, Netherlands
  • University Of California, San Francisco
    Research Associate
    University Of California, San Francisco Jan 2018 - Jun 2019
    San Francisco
  • Ucsf Helen Diller Family Comprehensive Cancer Center
    Postdoctoral Scholar
    Ucsf Helen Diller Family Comprehensive Cancer Center Jan 2013 - Jan 2018
    San Francisco
    HER2-HER3 signalingDeregulation of Src kinases in human cancers. Funded by Ramón Areces Foundation fellowship.
  • Consejo Superior De Investigaciones Científicas
    Postdoc
    Consejo Superior De Investigaciones Científicas Nov 2011 - Dec 2012
    Madrid Area, Spain
  • Universidad Autonoma De Madrid, Centro De Biología Molecular Severo Ochoa
    Ph.D Student Fpi Fellow
    Universidad Autonoma De Madrid, Centro De Biología Molecular Severo Ochoa Sep 2006 - Nov 2011
    Madrid Area, Spain
    Role of protein 4.1R in cell migration and tubulin cytoskeleton organization. Grade of Doctor by the Universidad Autónoma of Madrid with Excellent Qualification Cum LaudeFPI fellow funded by MICCIN (Spanish Ministry of Science and Innovation).
  • Erasmus Mc
    Ph.D. Student Fpi Fellow
    Erasmus Mc Sep 2010 - Dec 2010
    Rotterdam, Netherlands
    Role of protein 4.1R in regulating CLASP2 dynamics using TIRF microscopy. Fluorescence Recovery After Photobleaching (FRAP) to study cortical CLASP2 dynamics in living cells.Funded by FPI Short Term Fellowship
  • Erasmus Mc
    Ph.D. Student Embo Fellow
    Erasmus Mc Sep 2009 - Dec 2009
    Rotterdam, Netherlands
    Role of protein 4.1R in microtubule dynamics and organization at the leading edge of migrating cells.EMBO Short-Term Fellowship

Ana Ruiz-Saenz Skills

Crispr/cas9 Gene Editing Cell Biology Molecular Biology Cancer Research High Throughput Screening Signal Transduction Cell Culture Immunoprecipitation Western Blotting Confocal Microscopy Protein Expression Immunofluorescence Fluorescence Microscopy Colony Formation Assay Molecular Cloning Pcr Site Directed Mutagenesis Qpcr Rt Pcr Rna Isolation Flow Cytometry Apoptosis Biochemistry Genetics Science Cell Viability Assays Polymerase Chain Reaction Mouse Handling

Ana Ruiz-Saenz Education Details

  • Universidad Autonoma De Madrid
    Universidad Autonoma De Madrid
    Excellent Cum Laude
  • Universidad Autónoma De Madrid
    Universidad Autónoma De Madrid
    Molecular Biology

Frequently Asked Questions about Ana Ruiz-Saenz

What company does Ana Ruiz-Saenz work for?

Ana Ruiz-Saenz works for Cic Biogune

What is Ana Ruiz-Saenz's role at the current company?

Ana Ruiz-Saenz's current role is Principal Investigator at CIC bioGUNE.

What is Ana Ruiz-Saenz's email address?

Ana Ruiz-Saenz's email address is an****@****csf.edu

What schools did Ana Ruiz-Saenz attend?

Ana Ruiz-Saenz attended Universidad Autonoma De Madrid, Universidad Autónoma De Madrid.

What are some of Ana Ruiz-Saenz's interests?

Ana Ruiz-Saenz has interest in Civil Rights And Social Action, Politics, Education, Poverty Alleviation, Science And Technology, Disaster And Humanitarian Relief, Human Rights, Arts And Culture, Health.

What skills is Ana Ruiz-Saenz known for?

Ana Ruiz-Saenz has skills like Crispr/cas9 Gene Editing, Cell Biology, Molecular Biology, Cancer Research, High Throughput Screening, Signal Transduction, Cell Culture, Immunoprecipitation, Western Blotting, Confocal Microscopy, Protein Expression, Immunofluorescence.

Who are Ana Ruiz-Saenz's colleagues?

Ana Ruiz-Saenz's colleagues are Clara Garcia Vallicrosa, Blanca Calle Ciborro, Beatriz González Valle, Cristian Díaz Muñoz, Reyes Núñez Franco, Ana Poveda, Nuria Macías.

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