Ana Ruiz-Saenz Email and Phone Number
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Assistant Professor at Erasmus Medical Center in The Netherlands, working on elucidating the molecular mechanisms of cancer progression, aiming to turn laboratory discoveries into personalized cancer therapies. I am interested in characterizing the mode of function of HER2, and its partner HER3, in the pathological state of HER2 overexpression, in order to define a mechanistic basis for the development of novel therapeutic agents for the treatment of HER2-amplified cancers.As a postdoc fellow at the University of California San Francisco, I revealed new paradigms in cell signaling and cancer resistance in breast and colorectal cancers(published in Nature Cancer, Cancer Research and Oncogene, among others). In 2019, I established my own research group at Erasmus MC supported by the Marie Skłodowska-Curie Actions Programme and the Dutch Research Council. Our aim is to uncover the impact of aberrant tumor glycosylation on the efficacy of targeted therapies integrating clinical data, co-culture 3D immune-cancer spheroids and high-content live-imaging. Specifically, my lab is currently deciphering the impact of altered glycosylation on the response to HER2-targeting agents in breast cancer, including a recent and promising therapeutic agent developed by AstraZeneca.My experience in the US and Europe has enabled me to establish fruitful collaborations with international experts and the pharmaceutical industry. I have also actively participated in numerous conferences and outreach activities, including fundraising events and science communication events. And I am also a lecturer of the Molecular Medicine Master program at Erasmus Medical Center.
Cic Biogune
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Principal InvestigatorCic Biogune Dec 2023 - PresentBilbao-Bilbo, Basque Country, Spain -
Assistant ProfessorErasmus Mc 2021 - PresentRotterdam, South Holland, Netherlands -
Principal InvestigatorErasmus Mc Jul 2019 - Dec 2023Rotterdam Area, Netherlands -
Research AssociateUniversity Of California, San Francisco Jan 2018 - Jun 2019San Francisco -
Postdoctoral ScholarUcsf Helen Diller Family Comprehensive Cancer Center Jan 2013 - Jan 2018San FranciscoHER2-HER3 signalingDeregulation of Src kinases in human cancers. Funded by Ramón Areces Foundation fellowship. -
PostdocConsejo Superior De Investigaciones Científicas Nov 2011 - Dec 2012Madrid Area, Spain -
Ph.D Student Fpi FellowUniversidad Autonoma De Madrid, Centro De Biología Molecular Severo Ochoa Sep 2006 - Nov 2011Madrid Area, SpainRole of protein 4.1R in cell migration and tubulin cytoskeleton organization. Grade of Doctor by the Universidad Autónoma of Madrid with Excellent Qualification Cum LaudeFPI fellow funded by MICCIN (Spanish Ministry of Science and Innovation). -
Ph.D. Student Fpi FellowErasmus Mc Sep 2010 - Dec 2010Rotterdam, NetherlandsRole of protein 4.1R in regulating CLASP2 dynamics using TIRF microscopy. Fluorescence Recovery After Photobleaching (FRAP) to study cortical CLASP2 dynamics in living cells.Funded by FPI Short Term Fellowship -
Ph.D. Student Embo FellowErasmus Mc Sep 2009 - Dec 2009Rotterdam, NetherlandsRole of protein 4.1R in microtubule dynamics and organization at the leading edge of migrating cells.EMBO Short-Term Fellowship
Ana Ruiz-Saenz Skills
Ana Ruiz-Saenz Education Details
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Universidad Autonoma De MadridExcellent Cum Laude -
Universidad Autónoma De MadridMolecular Biology
Frequently Asked Questions about Ana Ruiz-Saenz
What company does Ana Ruiz-Saenz work for?
Ana Ruiz-Saenz works for Cic Biogune
What is Ana Ruiz-Saenz's role at the current company?
Ana Ruiz-Saenz's current role is Principal Investigator at CIC bioGUNE.
What is Ana Ruiz-Saenz's email address?
Ana Ruiz-Saenz's email address is an****@****csf.edu
What schools did Ana Ruiz-Saenz attend?
Ana Ruiz-Saenz attended Universidad Autonoma De Madrid, Universidad Autónoma De Madrid.
What are some of Ana Ruiz-Saenz's interests?
Ana Ruiz-Saenz has interest in Civil Rights And Social Action, Politics, Education, Poverty Alleviation, Science And Technology, Disaster And Humanitarian Relief, Human Rights, Arts And Culture, Health.
What skills is Ana Ruiz-Saenz known for?
Ana Ruiz-Saenz has skills like Crispr/cas9 Gene Editing, Cell Biology, Molecular Biology, Cancer Research, High Throughput Screening, Signal Transduction, Cell Culture, Immunoprecipitation, Western Blotting, Confocal Microscopy, Protein Expression, Immunofluorescence.
Who are Ana Ruiz-Saenz's colleagues?
Ana Ruiz-Saenz's colleagues are Clara Garcia Vallicrosa, Blanca Calle Ciborro, Beatriz González Valle, Cristian Díaz Muñoz, Reyes Núñez Franco, Ana Poveda, Nuria Macías.
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