Institute of Biochemistry - Biotechnology & Enzyme CatalysisProject: Protein Engineering for Industrial Flavor Production in Collaboration with Symrise AGMain tasks:– DNA library design using diverse cloning technologies and molecular biology methods– Development of high-throughput screening and method automation with a liquid handling robot – Invention disclosure report and patent application– Guidance of technical staff

Groningen Research Institute of Pharmacy - Chemical and Pharmaceutical BiologyProject: Designing Biocatalysts for Non-Natural CarboligationsMain Tasks:- Independent and proactive project management- Supervision of Bachelor and Master projects- Directed evolution of enzymes by site-directed and random mutagenesis- High-throughput screening of enzymatic variants using liquid handling automated workstations- Purification and characterization of enzyme variants- Design of enzymatic cascades for the production of pharmaceutical precursors- Chemical synthesis of substrates and reference compounds- Discovery of new non-natural enzyme activities

Institute of MicrobiologyMain Tasks: - Gene cloning, enzyme expression and purification, activity assays, 2-D electrophoresis, lab maintenance

Groningen Research Institute of Pharmacy - Chemical and Pharmaceutical BiologyProject: Biocatalytic Synthesis of GABA Analogue Precursors: Characterization of Two Enantiocomplementary ‘Michaelases‘ (Master thesis)Main tasks: - Characterization of enzyme variants, biocatalytic synthesis of pharmaceutical precursors, optimization of biocatalytic reactions, site-directed mutagenesis

Institute of MicrobiologyMain Tasks:- Gene cloning, enzyme expression and purification, lab maintenance

Department of New Materials and BiosystemsProject: Cell Interactions with the Extracellular Environment and Functional SurfacesMain Tasks:- Cell culture, spin coating, scanning electron microscopy