• Ensure efficient technical lab support/expertise to the different labs and to other departments.• Identify (technical) bottlenecks, perform root cause analysis and eliminate them according to expectations and provides customer response, be open for feedback to adjust service.• Initiate and follow-up on change controls, CAPAs, deviations.• Organize and plan your support and project activities, to timely implement and guarantee an efficient and effective output. Improves productivity and avoids unnecessary costs in relation to the assigned project, personnel and equipment budgets.• Responsible for the reliability for the generated results by analysts who are responsible for the designated tasks.Guarantee good documentation practices and data integrity information in an open and proactive manner to the team and other teams/departments, organisations. Know when and how to escalate.• Act to stimulate a positive, diverse and inclusive work atmosphere for the team.• Develop and provide scientific and technical knowledge.• Support on filing/regulatory submissions for marketing applications (BLA, MAA).• Department point of contact for audits and inspections.

•Technical expert role with respect to method development.• Plans and supports the execution of analyses of screening stability studies in line with thestability study protocol.• Approves the raw analytical data of method development, batch testing of non-GMP batches.Approves the raw analytical data related to method validation, batch testing of GMP batchesand GMP stability studies.• Makes disposition of the incoming goods related to IMP production or EU-certification.• Ensures that qualified equipment and premises are to be used.• Assists the Scientists – Analytical Development in documenting non-conformances.• Controls that the laboratory materials and samples are stored in line with the appropriatedocumentation in order to keep the required quality.• Interacts with Director Formulation Development and Production for access to the samplingbooth (for incoming quality control sampling) and cleaning validation and verification of GMPequipment.• Assists during (internal) audits and where required during meetings with Costumers• Responsible for knowledge building with regard to analytical techniques.• Reviewer of scientific reports and assists in meeting with Contract Giver, if requiredTechnical expert role with respect to Quality Control analysis (HPLC, UHPLC, KF, GC).• Plans and follows up the GMP analyses for GMP stability study time points in line with thestability study protocol.• Plans and follows up the GMP analyses for Quality Control release testing in line with theTechnical Quality Agreement.• Coordinates the purchase and the availability of starting materials prior to start of GMPanalysis.• Communicates with QA for follow up and strategy to be followed for non-conformances.• Assists the Scientists – Analytical Development with the writing of the relevant documentation.• Responsible for resolving and discussing quality related issues with QA/QP; oversees theinitiation of non-conformances within the department by trained personnel

• Dissolution lead for early phase projects (Immunology, Oncology) for oral or liquid drug product formulations. • Responsible for the analytical method development for peptides and oligonucleotides in the dissolution sciences department. • Participation in project meetings and responsible for presenting and documenting the results (GMP and non-GMP) to the team (eg. Dissolution Scientific support, AD-SI; DPD-SI; biopharm). Participation in the post-doc community activities and conferences/workshops. • Responsible for coordinating the project activities at CRO’s and internally. • Coordinates and/or performs QC dissolution method robustness, qualification, validation and transfer activities according to GMP. • Contributes to setting dissolution specification limits. • Writes technical reports and other documents that record data or results. • Performs effective troubleshooting where needed for development of marketed products. • Operates laboratory equipment and analytical instrumentation and ensures it proper operation and maintenance. • Leads and/or contributes to scientific initiatives and work groups (eg. oligonucleotides platform).

LC-Orbitrap-MS/MS analysis; Identification of extractables and leachables from medical devices, API, and materials (plastics/rubbers, etc); Reporting the analytes are based on GMP and GLP (ISO 17025) guidelines

PhD theme "Developing non-invasive methods for monitoring human body burdens".Main goals and experience:-Optimization of new extraction methods based on microextraction (e.g. DLLME) and solid-phase extraction (SPE) and their analytical validation.-Assessment of the human exposure to different classes of environmental organic pollutants such as perfluoroalkyl substances (PFAS), phthalate esters (PEs) and organophosphate esters (flame retardants) by using non-invasive samples (e.g. hair, nails, urine).-Quantification and identification using analytical techniques (UPLC-MS/MS, UPLC-DAD-MS, LC-ORBITRAP-MS, HR-GC-MS).-Method development, validation, QC in GLP enviroment-Development of in vitro assays using human liver microsomes (HLM) for assessing the phase I and phase I metabolites formed of emerging flame retardants (V6, BDP) and plasticizers (ATBC, DEHPT, DEHA, DPHP) using CYPs (Cytochrome P450), PONs (paraoxonases), CEs (Carboxylesterases), SULT (Sultransferases), GLUC (Glucuronidases)-Use of various analytical softwares (Xcalibur (Thermo Unicam), MassLynx/TargetLynx (Waters))-Statistical analysis (SPSS Inc, STATISTICA)

Research in the project named "Aroma Profiles of Honey - A system of classification and appreciation of Portuguese honey", funded by National Beekeeping Plan 2008-2010Main goals and tasks:Analytical method development and validation Characterization of volatile/aroma compounds in food samples by GC-MS-Identification and quantification of organic compounds by liquid chromatography diode array detection (HPLC-DAD)Evaluation of antioxidant activity in biological and food samples by UV-Vis (DPPH radical scavenging, ferric reduction antioxidative power (FRAP assay), total phenolics content (Foiln-Ciocalteu), Photochemiluminescence (PCL) Assay)Mineral characterization of solid matrices: (acid digestion,calcination), determination of major (e.g. Fe, Ca, Mg, K,etc) and minor mineral (Ni, Zn, Cd, etc) content by Atomic Absorption Spectrophotometry associated to flame/graphite furnace atomizationHoney sample quality control (pH, conductivity, free acidity, moisture) according to EU 2001/110 DirectiveAdditional Research tasks:Trace analysis (hydrocarbons, pesticides, PAHs, VOCs)Terpene, phenols and benzene derivatives quantification by GC-MSCharacterization and use of a bio-oilAcid-base fractionationCharacterization of volatiles and nonvolatiles by gas chromatography coupled to mass spectrometry (GC-MS)Characterization of organic compounds by infrared spectrometry (FTIR)Sample preparation techniques (SPE, SPME, HS-SPME, DLLME, SBSE, SPE-DLLME)Optimization/development and validation (linearity, precision, LOD, LOQ, repeatibility) of microextraction methods for pesticides removal from water samplesChemical chacarterization (GC-MS, GC-FID, FTIR) of bio-oil obtained by pyrolysis of chicken beds Quantitative analysis of volatiles present in eucalypt samples▪Professor of Food Quality II subject (practical)-Food Quality and Tecnhology Master, academic year 2010/2011 and 2011/2012