• Developed bottom-up chemical proteomics platform to semi-quantitatively monitor RNA-protein interactions using covalent, cysteine-reactive chemistries targeting previously undruggable protein regions • Validated novel RNA-binding proteins with MS- and gel-based approaches • Screened heterocycle libraries and identified several potent inhibitors of selenocysteine elongation factor• Wrote software to manage, analyze and interpret large proteomics data sets• Maintained Q-Exactive… Show more • Developed bottom-up chemical proteomics platform to semi-quantitatively monitor RNA-protein interactions using covalent, cysteine-reactive chemistries targeting previously undruggable protein regions • Validated novel RNA-binding proteins with MS- and gel-based approaches • Screened heterocycle libraries and identified several potent inhibitors of selenocysteine elongation factor• Wrote software to manage, analyze and interpret large proteomics data sets• Maintained Q-Exactive Plus mass spectrometers and various liquid chromatography systems• Effectively mentored undergraduate researchers, resulting in distinguished degree designations Show less

• Performed thorough due diligence on 10+ life science ventures, resulting in four investments• Constructed investment memorandums on life science deals• Assisted in screen activities for new investments

• Built financial models for potential investment opportunities• Performed due diligence and constructed investment memorandums • Assisted portfolio companies with market research

• Formulated commercial buffers and conjugated antibodies• Utilized cGMP (current Good Manufacturing Practice) and cGDP (current Good Documentation Practices) to ensure product quality• Streamlined processes and created new SOPs (Standard Operating Procedures) for new instrumentation and formulations• Attended monthly safety meetings and inspected labs for compliance

• Designed and executed formulation stability studies for bi-specific and monoclonal antibody therapeutics through design, execution, and report generation• Trained new employees on Amgen SOPs and instrumentation

• Developed novel purification strategies using affinity chromatography• Elucidated secondary structural characteristics of a novel negative feedback regulator, AggR-activated Regulator (AAR), and probed structural response to temperature

• Aided in software design for high-throughput molecular dynamics simulations