Angharad Walters, Phd

Angharad Walters, Phd Email and Phone Number

Cell Biologist | Organoid Technology | High-content Imaging | Lipid Nanoparticles @ Hone Bio
Angharad Walters, Phd's Location
Cardiff, Wales, United Kingdom, United Kingdom
About Angharad Walters, Phd

As an R&D Scientist at Molecular Devices, I applied my PhD in Cancer & Genetics and expertise in 3D cell culture to expand and commercialize patient-derived organoids for drug discovery and development. I have 7+ years of lab experience in both academia and industry, working with cutting-edge technologies such as CRISPR/Cas9 gene editing, high-content imaging, and NGS.I have established and cultured over 40 novel organoid lines from adenomatous polyposis patients, and identified novel tumour drivers and potential drug targets using various in vitro and cell-based assays. Collaboration with biotech has led to patenting and commercial bioreactor scale up of select lines. Throughout my career, I have delivered award-winning scientific presentations at 30+ conferences and public events, and communicated effectively with diverse stakeholders. I am always eager to learn new skills, expand my network, and contribute to the biotech community. Please feel free to each out here on LinkedIn or via Twitter (@AngharadWalters). I look forward to speaking with you!

Angharad Walters, Phd's Current Company Details
Hone Bio

Hone Bio

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Cell Biologist | Organoid Technology | High-content Imaging | Lipid Nanoparticles
Angharad Walters, Phd Work Experience Details
  • Hone Bio
    Cell Biologist
    Hone Bio May 2024 - Present
    City Of Bristol, England, United Kingdom
  • Cardiff University School Of Medicine
    Doctoral Researcher, Cancer Research
    Cardiff University School Of Medicine Jul 2019 - Dec 2023
    Cardiff, Wales, United Kingdom
    KESS2 Funded collaboration between welsh biotech company Cellesce (now Molecular Devices) and the Division of Cancer & Genetics, School of Medicine. Accomplishments:•Established and cultured over 40 novel human small intestinal organoid lines from adenomatous polyposis patient tissue.•Achieved bioreactor expansion and commercialisation/patenting of select lines in collaboration with biotech.•Implemented CRISPR/Cas9 gene editing, high content microscopy (Opera phenix-PerkinElmer), flow cytometry, fluorescence/luminescence cell based assays, and molecular biology techniques to characterise lines of interest and elucidate novel tumour drivers and potential therapeutics.
  • Cardiff University School Of Medicine
    Pgr Student Representative, Division Of Cancer And Genetics
    Cardiff University School Of Medicine May 2020 - Apr 2021
    Communicated critical information to the student cohorts during COVID lab closures. Attended meetings with senior division members, acted as a near-peer mentor, organised seminar series, hosted informal student events, organised and chaired Postgraduate Symposiums.
  • Molecular Devices
    Research And Development Scientist, 3D Organoid Technology
    Molecular Devices Jun 2023 - Nov 2023
    Cardiff, Wales, United Kingdom
    Employment during the write up period of PhD.Carried out bioreactor expansion of cancer patient derived organoids for commercial use to GDP standard as well as their use in drug assays. Role also included writing and updating SOPs/COSHH forms, maintaining laboratory stock, and implementing process improvements.
  • University Of Oxford
    Research Assistant, Ngs Library Preparation
    University Of Oxford Oct 2016 - Jan 2019
    Oxford, United Kingdom
    Promoted to the library preparation team to prepare PCR based DNA and RNA libraries for commercial Illumina Next Generation Sequencing Projects. Completed hundreds of projects often simultaneously and to tight deadlines, mentored and trained junior lab members.
  • University Of Oxford
    Laboratory Technician, Quality Control
    University Of Oxford Oct 2016 - May 2017
    Employment at the Wellcome Trust Centre for Human Genetics (WTCHG). Initially in quality control (QC), conducting qualitative and quantitative analysis of hundreds of DNA/RNA samples.
  • European Cancer Stem Cell Research Institute, Cardiff University
    Final Year Project Student, Cancer Immunology
    European Cancer Stem Cell Research Institute, Cardiff University Sep 2015 - Jun 2016
    Cardiff, United Kingdom
    Gained experience investigating the immune systems role in cancer. Characterised immune infiltrate in Wnt activated murine intestine following neutralising HMGB1 (The high-mobility group protein B1) treatment.
  • Institute Of Medical Genetics, Cardiff University
    Research Technician, Cancer Genetics
    Institute Of Medical Genetics, Cardiff University Aug 2015 - Sep 2015
    Cardiff, United Kingdom
    Summer employment as a lab technician during my undergraduate degree. Involved working on the genetic mechanisms of adenomatous polyposis syndromes, validating putative pathogenic variants found by high throughput genomic technologies.
  • Institute Of Medical Genetics, Cardiff University
    Professional Training Year Student, Medical Genetics
    Institute Of Medical Genetics, Cardiff University Jul 2014 - Jun 2015
    Cardiff, United Kingdom
    Worked within the Tuberous Sclerosis (TSC)/ Polyposis research group during the professional training year of my undergraduate degree. Gained experience of genomic technologies including targeted ultra deep sequencing and exome sequencing. Also developed expertise culturing murine derived AML and MEF cell lines.
  • Absolute Drinks, Pembrokeshire
    Bar Staff
    Absolute Drinks, Pembrokeshire 2009 - 2015
    Pembrokeshire
    Part-time bar and waitress work during High School and University at events held around Pembrokeshire.

Angharad Walters, Phd Education Details

Frequently Asked Questions about Angharad Walters, Phd

What company does Angharad Walters, Phd work for?

Angharad Walters, Phd works for Hone Bio

What is Angharad Walters, Phd's role at the current company?

Angharad Walters, Phd's current role is Cell Biologist | Organoid Technology | High-content Imaging | Lipid Nanoparticles.

What schools did Angharad Walters, Phd attend?

Angharad Walters, Phd attended Cardiff University / Prifysgol Caerdydd, Cardiff University / Prifysgol Caerdydd.

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