Anima Ghosal work email
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Anima Ghosal personal email
Senior Level Drug Metabolism Scientist recognized for managing and collaborating with cross-functional teams to produce consistently superior results in discovery and development. Extensive experience in the Pharmaceutical Industry includes preclinical discovery and development, enzymology, in vitro metabolism, identification of Phase I and Phase II enzymes responsible for the metabolism of new drugs, enzyme kinetics, enzyme inhibition/induction, drug-drug interaction, covalent protein, DNA binding studies and CRO monitoring. Regulatory Affairs training reinforces the required skills of a regulatory professional in a pharmaceutical industry. Recognized for collaboration, innovation, and attention to detail across projects and organization.
Drug Discovery And Drug Development
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ConsultantDrug Discovery And Drug Development Jan 2014 - PresentGreater New York City Area
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Adjunct Assistant ProfessorDepartment Of Pharmacology & Toxicology, Ernest Mario School Of Pharmacy, Rutgers University 2015 - 2016Piscataway, Nj
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Senior Principal Scientist/Associate Principal ScientistMerck Nov 2009 - 2013Development support: Responsibility includes identification of Phase I (cytochrome P450, FMO, MAO, AKR) and Phase II enzymes (UGTs) responsible for the metabolism of new drugs, enzyme kinetics, and enzyme inhibition studies. Also responsible for drug-drug interaction studies, support in vitro scale-up and characterization of metabolites of new drugs, incubation of hepatocytes, characterization of recombinant human P450 and UGT enzymes, covalent protein binding studies, and reactivity of acyl glucuronides.CRO Monitoring: Monitor cytochrome P450 inhibition and induction studies (XenoTech, LLC) for NDA submission. Support Toxicology Group for ex-vivo dog P450 induction studies. Discovery support: Issue driven. -
Senior Principal ScientistSchering-Plough Research Institute 1998 - 2009Development support: Responsibility includes identification of Phase I (cytochrome P450, FMO, MAO, AKR) and Phase II enzymes (UGTs) responsible for the metabolism of new drugs, enzyme kinetics, and enzyme inhibition studies. Also responsible for drug-drug interaction studies, support in vitro scale-up and characterization of metabolites of new drugs, incubation of hepatocytes, characterization of recombinant human P450 and UGT enzymes, covalent protein binding studies, and reactivity of acyl glucuronides.CRO Monitoring: Monitor cytochrome P450 inhibition and induction studies (XenoTech, LLC) for NDA submission. Support Toxicology Group for ex-vivo dog P450 induction studies.Discovery support: Responsibility includes identification of Phase I (cytochrome P450) enzymes capable of metabolizing new chemical entity using 96-well plates. -
Research AssociateHoffmann-La Roche 1993 - 1996In vitro assay development using HPLC (midazolam, caffeine metabolism with hepatic rat, human and cDNA-expressed human cytochrome P450 microsomes), preparation and catalytic assays with human intestinal microsomes, enzyme kinetics, enzyme inhibition and capillary electrophoresis. Develop model in vitro assay systems evaluating drug biotransformation in order to predict drug-drug interactions in clinical trial, enzyme induction, identification of GSH-conjugate by LC/MS and covalent protein binding studies to support drug development.
Anima Ghosal Skills
Anima Ghosal Education Details
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Biochemistry/Botany
Frequently Asked Questions about Anima Ghosal
What company does Anima Ghosal work for?
Anima Ghosal works for Drug Discovery And Drug Development
What is Anima Ghosal's role at the current company?
Anima Ghosal's current role is Drug Metabolism Expert | Enzymology | CYP450.
What is Anima Ghosal's email address?
Anima Ghosal's email address is an****@****rck.com
What schools did Anima Ghosal attend?
Anima Ghosal attended University Of Calcutta.
What skills is Anima Ghosal known for?
Anima Ghosal has skills like Biotechnology, In Vitro, Glp, Lc Ms, Biomarkers, Protein Chemistry, Hplc, Drug Development, Clinical Trials, Lifesciences, Cro, Drug Discovery.
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