Anna Hickey Email & Phone Number

Pearland, Tx, Us

United States

- Designed and performed surface plasmon resonance (SPR) to support hit identification, hit-to-lead, and lead optimization stages of oncological small molecule drug discovery projects - Trained colleagues to proficiency in SPR assay execution and data analysis- Assessed biomolecule binding kinetics and affinity using bio-layer interferometry (BLI) on the Octet RED384 system- Pioneered the establishment of DNA-encoded library screening technology onsite- Contributed routine biophysical, biochemical, and cell-based assays to project assay funnels - Researched, recommended, and implemented new instrumentation to expand laboratory capabilities- Transformed data analysis and reporting workflows by incorporating new software and other tools - Analyzed complex data using multiple data analysis platforms, including Genedata Screener, Biacore S200 Evaluation Software, Graphpad Prism, and Microsoft Excel- Co-led administration of data analysis software, Genedata Screener- Orchestrated shipments to CROs for assay services- Fostered the adoption of a new electronic notebook system by becoming an early tester, departmental superuser, and institution-wide educator of principal investigators and peers- Presented experimental results during project team and departmental meetings- Represented MD Anderson in interactions with vendors and external scientists- Attended seminars, conferences, and other external training

Houston, Texas, United States

Pearland, Texas

- Tutored students of all ages in math, science, reading and writing, with a primary focus on upper level math and science, including SAT/ACT preparation and college-level courses - Taught “Math Edge” – an advanced math class for all ages – monitoring up to eight students at one time- Mentored and personally engaged students in preparation for instruction time - Evaluated and recorded student progress during and after each session- Helped students raise school grades by 30% or higher

- Designed and executed "Systematic Evolution of Ligands by Exponential Enrichment" (SELEX) to discover aptamers against customer-specified targets, daily utilizing PCR, DNA purification, enzymatic digestion, and gel electrophoresis- Characterized aptamer-target binding using BLI and micro-scale thermophoresis (MST)- Conjugated haptens to carrier proteins, and aptamers to gold nanoparticles, at varying labeling ratios- Carried out high-throughput screening using DNA microarrays- Developed aptamer-based applications, including lateral flow assays - Performed DNA library preparation, emulsion PCR, and sequencing prep on the Ion Torrent platform for Next Generation Sequencing (NGS)- Presented research in weekly company-wide meetings- Represented company off-site during collaborations- Assisted Operations to organize and maintain inventory

Pearland, Tx

University Of Oregon

- Developed a DNA hybridization based pull-down assay using streptavidin-coated magnetic beads to efficiently and specifically isolate platinated biomolecules from a complex matrix- Used click chemistry to label DNA oligonucleotides and click-enabled platinum compounds with fluorophores or hexynyl-functionalized DNA probes- Carried out time course experiments to study the stability of DNA crosslinked to bovine serum albumin (BSA) through platinum adducts in fetal bovine serum- Presented research at regular lab meetings and poster symposiums sponsored by the University of Oregon and the American Chemical Society - Research project culminated in an honors thesis, which “Passed with Distinction” and led to publication

School Of Architecture And Allied Arts, University Of Oregon, Eugene, Or

- Drafted official correspondence between the program and program supporters- Updated and organized student progress files- Tracked incoming student applications- Locally distributed promotional materials - Mailed packets and letters- Other office duties as assigned