Anna Lyubetskaya Email and Phone Number
As a computational biology team lead and an individual contributor, I partner with oncology R&D teams to propose new drug targets and advance pre-clinical programs. I guided multiple program decisions, proposed and implemented strategies for target identification leveraging patient molecular data, and developed enterprise-wide pipelines for genomics data analyses.Over a decade of post-PhD experience, I employed high-throughput data, multi-omics integration, and machine learning across diverse domains, including tumor-intrinsic cancer resistance, personalized cancer vaccines, metabolic disorders, and infectious diseases.
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Associate Director Of Computational BiologyMetaphore Biotechnologies Aug 2024 - Present
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Senior Principal ScientistBristol Myers Squibb Apr 2022 - May 2024Cambridge, Massachusetts, United StatesIn collaboration with drug discovery collaborators, spearheaded the identification and validation of novel oncology targets in 2 solid tumor indications within a global, cross-functional setting. As a result, developed a complete analytical and experimental framework that leveraged machine learning, artificial intelligence, and image analysis, multi-modal spatial transcriptomics and pathology patient data, and pooled functional genomics screens, facilitating the generation of novel target and biomarker hypotheses. -
Principal ScientistBristol-Myers Squibb Sep 2019 - Apr 2022Partnered with 6 oncology drug discovery programs across stages of development, contributing predictive and pharmacodynamics biomarkers, translational hypotheses, and patient disease stratifications. Pioneered quantitative analyses of state-of-the-art genomics technologies – including spatial transcriptomics, scRNA-Seq, Perturb-Seq, and cfDNA/RNA – to drive biomarker strategies.
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Senior Computational BiologistGenocea Feb 2019 - Jul 2019Led clinical and research computational work to facilitate a personalized neoantigen cancer vaccine Phase 1/2a clinical trial.
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Computational BiologistGenocea May 2018 - Feb 2019Contributed to the initiation of a personalized neoantigen cancer vaccine Phase 1/2a clinical trial by providing analytics for a proprietary cell assay and by investigating the competitive space.
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Data ScientistCopyright Clearance Center Feb 2017 - May 2018Co-developed a scalable data science architecture for knowledge extraction from unstructured scientific text and construction of disease-focused relationship graphs. As the product owner, led an engineering team in prototyping the product. Additionally, established data science workshops for marketing and sales departments -
Senior BioinformaticianBeth Israel Deaconess Medical Center Apr 2016 - Jan 2017Supervised the bioinformatics analysis and integration of bulk and single-cell genomics and epigenomics datasets for a variety of metabolic projects for the Functional Genomics and Bioinformatics Core. -
BioinformaticianBeth Israel Deaconess Medical Center Sep 2014 - Apr 2016Advanced studies of obesity and insulin resistance by developing computational pipelines and performing various genomics and epigenomics computational analyses in collaboration with 5 clinical and experimental teams.
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Ph.D Student In BioinformaticsBoston University Sep 2009 - Aug 2014Developed and validated a novel computational framework for analysis of bacterial ChIP-Seq data as a part of a cross-functional consortium. Refined and expanded existing regulatory bacterial networks through the integration of binding and expression data focusing on non-canonical transcriptional regulation.
Anna Lyubetskaya Education Details
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Boston UniversityBioinformatics -
Moscow State UniversityBioinformatics And Bioengineering
Frequently Asked Questions about Anna Lyubetskaya
What company does Anna Lyubetskaya work for?
Anna Lyubetskaya works for Metaphore Biotechnologies
What is Anna Lyubetskaya's role at the current company?
Anna Lyubetskaya's current role is Computational Biology Team Lead, Drug Discovery, Oncology.
What schools did Anna Lyubetskaya attend?
Anna Lyubetskaya attended Boston University, Moscow State University.
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