Bioanalysis of in vivo PK and PD samples using different sample preparation methods. Quantification and identification with LC-MS/MS.

Support projects with biotransformation data and knowledge. - Presentation of the data to the DMPK project teams. - Responsible for elucidating MS spectra to identify metabolite structures.

Involved in metabolite identification of drug compounds including biotransformation support to projects. Bioanalysis of in vivo samples and in tissues, phys-chem analysis of drug compounds. Sample preparation performed both manually and with liquid handling robots (Tecan). Quantification and identification with LC-MS/MS.

Bioanalysis of drug compounds in plasma samples according to GLP (Good Laboratory Practice) including method development and method validations.

Analysis and quantification of endogenous substances in blood and urine using LC-UV, electrochemical and fluorescence detection. Documentation and handling of patient information in accordance to standards of an accredited laboratory.