Anna Pavlova Email & Phone Number

San Bruno, CA, US

Foster City, CA, US

Analytical Lifecycle Management in QC Biologics Team

Brisbane, California, US

Brisbane, California, US

Brisbane, California, US

Brisbane, California, US

• Led the development of biochemical and biophysical analytical methods for characterization and release of AAV-based gene therapy products. Support Formulation development and Process development groups in.
• Developed analytical methods for characterization and release of gene therapy products including HPLC, SEC-MALS, DLS, CE-SDS, cIEF, ddPCR, qPCR, ELISA, impurity assays etc.
• Led development, qualification and transfer of analytical methods including HPLC, ELISA, PCR based methodologies in support of preclinical, early and late phases clinical trials.
• Oversaw analytical method development and testing to support formulation development for AAV gene therapy products. Established and maintained effective collaboration between the teams.

New York, NY, US

Completed projects and gained insights from different types of data with Supervised and Unsupervised machine learning techniques ( Regression, Clustering, Ensemble Models, NLP etc. ) using various Python libraries (pandas, numpy, sklearn, nltk etc.)

-Developed and Validated Analytical Methods for Quantitative and Qualitative Characterization of Biologic Drugs. -Served as Subject Matter Expert on Analytical Methods including q-PCR, ELISA, BLI, Capillary Electrophoresis (CE), MALS, HPLC, Western Blot, Enzymatic Assays etc. -Authored and Reviewed Protocols, Reports, Documentation in support of New Drug.

San Diego, California, US

Lead Analytical Development (AD) department in Analytical Method Development and Validation for Pre-Clinical, Phase I/II clinical trials material. Analytical support of GMP manufacturing and process development in production of Recombinant Monoclonal Antibodies and Proteins.

San Diego, California, US

- Planned and Established Analytical Development Department/Lab.- Developed, optimized and validated Analytical Methods to support Manufacturing Process Development, GMP material release, Feasibility, Pre-formulation, Stability of biologic drugs. - Subject Matter expert in analytical techniques, including HPLC, CE, ELISA, SDS-PAGE, IEF, Western Blotting.

La Jolla, CA, US

Developed functional assays to analyze structure/function of G-protein-coupled receptors (GPCRs). Demonstrated bacterially expressed mammalian GPCRs, such as CXCR1, remained functional upon reconstitution in detergents, liposomes and phospholipid membrane.

Santa Barbara, CA, US

Elucidated Tau protein aggregation mechanisms while developing novel Dynamic Nuclear Polarization technique for studying biologic/protein systems.

Atlanta, Georgia, US

- Exploratory research of physical forces at nano-scale (nanotribology) in application to studying physical properties of nano-materials, using Atomic Force Microscopy in the lab of Elisa Riedo. - Theoretical and computational research on RNA world and Origins of Life, based on theoretical model by Ronald Fox. Performed molecular modeling analysis with.

US

Executed collection of payments on past due invoices from major client accounts.Managed warehouse inventory and daily shipments of computer equipment to company clients. Supported sales and technical service departments by managing customer orders and inventory.

Doctor Of Philosophy (Phd), Biochemistry / Biophysics

Bachelor Of Science (Bs), Physics