Ann Devine Email & Phone Number

Philadelphia, PA

March of Dimes grant that focuses on placental function. To study the elevation of acylcarnitines and increased prostaglandins in sPTB placentas relative to term birth placentas 1. Trophoblast isolation – Proficiency in isolation of trophoblasts from third, second and first trimester placenta 2. Developed second trimester vilous explant model 3. Migration.

Huntingdon Valley, PA 19006

Director of Cellular Research: Dr. Mark ConnellySupervisor: Manager of CellSearch R&D: Dr.Chandra RaoDevelopment of an FDA approved reagent assay kit and methods for the detection of circulating tumor cells from blood*Create novel marker reagents and detection of rare cells using the Veridex CellSearch System*Adapt known biomarkers for analysis of CTC’s in.

West Chester, PA (contracted By Aerotec 4/2006 Hired By Cephalon 1/2007

Vice President of Research: Dr. Jeff VaughtDirector: Dr. Bruce RuggeriSupervisor: Dr. Susan Jones-Bolin, Dr. Matt SeaveyContracted to perform in vitro, cell based assays and in vivo assays for the Bendamustine project and to advance lead compounds into drug development.*Determination of bendamustine concentration in various cell lines using the MTS.

Spring House, PA

Team Leader: Dr. Dana JohnsonSupervisor: Dr Jan Sechler*Performed in vitro, cell based and in vivo assays for the c-Met project to advance lead compound into drug development Primary screen:c-Met in vitro kinase autophosphorylation assay. Secondary c-Met Cell Elisa assay*Developed assays for the assessment of in vivo activity S114 Mouse Tumor Xenograph PD.

Spring House, PA

Director: Dr. Charlie BowdenSupervisor: Dr. Dave End, Dr. Bob Tuman*Responsibilities for the Farnesyltransferase project were directed to the advancement of Zarnestra for clinical developement and FDA approval Cell Proliferation Support clinical work for Zarnestra with apoposis studies using flow cytometry Immunoblotting for different ras mutations.

Spring House, PA Robert Wood Johnson Research Institute

Director: Dr. Jeffery VaughtSupervisor: Dr. Barry DubinskyResponsibilities for the Anxiolytic project were a variety of in vivo assays to determmine bendodiazepine binding, behavioral pharmacology and safety of novel compounds Metrazol induced seizure Conflict test Ethanol Induce narcosis Precipitated withdrawal Cloniding induced madriasis Apomorphine.

Great Valley, PA

Purification and processing of antibodies for medical diagnostic kits and running quality assurance tests for antibody purity

Philadelphia, PA

Supervisor: Dr. Michael C. PhillipsSeparation and electrophoresis of lipoprotein fractions. Support work for the graduate students with electronmicroscopy and chromatofocusing.

B.S., Biology

Education record