Anne Sophie Gleinich, Ph.D. Email & Phone Number

Hannover, Lower Saxony, Germany

• leading a team of 6 in the field of mass spectrometry analysis for biologic/biosimilar products (incl. on-line liquid chromatography)
• developed and established new analytical LC-MS methods for 6+ biologic/biosimilar products
• conducted 15+ forced degradation and stability studies for various biologic/biosimilar products
• established critical parameters of various biologic/biosimilar products that we identified via forced degradation and stability studies, and partly guided dossier content
• 2 products reached marked approval (FDA and EMA) with methods designed and data derived from our team
• gained broad insight into overall biopharmaceutical development (CLD, USP, DSP, DPD), enabling me to provide valuable information, insight, and strategy

Complex Carbohydrate Research Center (CCRC), United States

• expertise in mass spectrometry (+ on-line HPLC) for protein analytics and glycan analytics including design of experiment, sample preparation, data acquisition, data analysis and interpretation, method development &.
• project manager of 15+ projects including10+ glycomic and proteomic projects analyzed via LC-MS/MS, ESI-MS/MS, and MALDI-MS3+ projects involving peptidoglycan analysis and characterization via GC-MS or LC-MS/MS2+.
• coordinator of service work and collaborations with a variety of internal and external partners, such as research groups, pharmaceutical companies, food manufacturing businesses, etc.
• instructor for the Complex Carbohydrate Research Center’s Hands-On-Training Courses

Department Of Chemistry, United Kingdom

• interaction studies/kinetic studies of (glyco)proteins of interest conducted via the optical analytical methods of Bio-Layer Interferometry (BLI) and Surface Plasmon Resonance (SPR)
• instruments worked with: ⇨ BLI: BLItz® System and Octet® RED96 System ⇨ SPR: ProteOn™ XPR36 Protein Interaction Array System
• access to the Octet® RED96 System is kindly provided by Professor Gibson's research group

Warwick Medical School, United Kingdom

• MB ChB CBL 𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗖𝗮𝘀𝗲𝘀 𝟭 facilitationMy role as a facilitator was to guide the group through the discussion, to ensure they met the learning objectives, and I encouraged their reflections on the learning.
• to integrate and expand knowledge on the areas covered in the previous academic year
• to provide a graded transition to the practical issues and improvement of a learning style needed for learning in the clinical environment
• support for the students to develop their skills in critical analysis of clinical information, team working and communication
• application of a problem-based approach to medical history taking and examinationThese aims are realised by working through a hypothetical medical case, that incorporates and builds upon their prior knowledge and.

Complex Carbohydrate Research Center (CCRC), United States

• structural analysis of the glycans attached to the glycoproteins of interest via mass spectrometry methods MALDI-ToF and nanoLC-MS/MS
• supervised training in the lab of CCRC investigator Dr Azadi provided an invaluable insight into the fields of glycomics and glycoproteomics including ⇨ sample preparation ⇨ data acquisition ⇨ data.
• J1-Exchange-Visitor Student-Intern for 11 weeks during PhD Research Project

Liverpool School Of Tropical Medicine, United Kingdom

• examination of the interaction between the glycoprotein of interest and receptors on primary human immune cells via flow cytometry
• supervised training in flow cytometry at the Flow Cytometry Service (LSTM)
• research group led by Dr Britta Urban kindly facilitated this collaboration
• collaborative work for 7 weeks during PhD Research Project

Warwick Medical School, United Kingdom

• MB ChB CBL facilitationThe facilitation is provided in small learning groups of around ten students. The students are supported to integrate their learning across the
• biomedical sciences
• social sciences
• clinical sciencesas well as to apply this learning to medical practice and, furthermore, to develop □ team working skills □ communication skills □ professional skills These aims are realised by working through a.

Institute Of Pharmacology And Clinical Pharmacy, Germany

• research techniques: protein analysis ___________________ PAGE, Western Blotenzyme chemistry _________________ activity assays, differential centrifugationcell culture ________________________ culturing of human cell.
• research topic: Alzheimer's Disease
• resulted in 2 co-authorships (please see the section 'Publications')

Ph.D. Student, Medical Sciences

Activities and Societies: Student-Staff Liaison Committee - Medical PGR SSLC (former Student Experience Representative and former.

Diploma (Msc Equivalent), Biochemistry, First-Class Honours

Activities and Societies: University choir ESG-Chor Major Field of Study: Biophysical Chemistry Minor Field of Study: Pharmacology and.