Annie Tran Email & Phone Number

Philadelphia, Pa, Us

Philadelphia, Pennsylvania, United States

Philadelphia, Pennsylvania, United States

• Led upstream process training sessions, enhancing cross-functional collaboration for seamless technology transfer at WuXi Advanced Therapies.• Oversaw client projects, ensuring high-quality injectable viral vectors and providing scientific support in client meetings.• Collaborated with MSAT and MFG teams for successful client technology transfer, pilot runs, and manufacturing runs.

Philadelphia, Pennsylvania, United States

• Developed scalable upstream processes for AAV production platform using bioreactor technology, reducing costs and improving production efficiency.• Optimized and scaled processes for various bioreactor volumes, ensuring consistency and reproducibility.• Created process reports, SOPs, and batch records for compliance with regulatory standards.

Philadelphia, Pennsylvania, United States

• Managed high-throughput screening of 3000 HEK293 clones via VIPS system for optimal cell line selection.• Developed small-scale shaker flask experiments using DoE principles, achieving a 10-fold increase in viral titer.• Utilized ddPCR, qPCR, ELISA, and FACS-based GFP analysis techniques for accurate virus titer quantification.

Philadelphia, Pennsylvania

The purpose of this project is to characterizing the role of EXT1 on breast cancer growth. Glycosylation is the process of modification in which carbohydrate is linked to proteins to form glycoconjugates, and the enzyme facilitates this process is glycosyltransferases. Glycosylation involved in the progression and development of tumor and metastasis. EXT1 is an glycosyltransferase which is highly amplified in breast and ovarian cancers. Knocking down EXT1 can affect breast cancer cell growth… Show more The purpose of this project is to characterizing the role of EXT1 on breast cancer growth. Glycosylation is the process of modification in which carbohydrate is linked to proteins to form glycoconjugates, and the enzyme facilitates this process is glycosyltransferases. Glycosylation involved in the progression and development of tumor and metastasis. EXT1 is an glycosyltransferase which is highly amplified in breast and ovarian cancers. Knocking down EXT1 can affect breast cancer cell growth and survival. Show less

Greater Philadelphia Area

The purpose of this project is to investigating the role of Big Potassium Channel (BKCa Channel) in mitochondrial ROS production. BKCa channels are located in the plasma membrane of cardiomyocytes, and play an important role in neuronal excitability and muscle contraction. They are also shown to regulate mitochondrial ROS production through increase in calcium influx. In this project, we use different pharmacological agents to induce the closure/opening of BKCa channel and monitor the… Show more The purpose of this project is to investigating the role of Big Potassium Channel (BKCa Channel) in mitochondrial ROS production. BKCa channels are located in the plasma membrane of cardiomyocytes, and play an important role in neuronal excitability and muscle contraction. They are also shown to regulate mitochondrial ROS production through increase in calcium influx. In this project, we use different pharmacological agents to induce the closure/opening of BKCa channel and monitor the production of ROS using spectrophotometric. Show less

Chemistry Lab, Chemistry And Biochemistry Department

Chemistry Lab, Chemistry And Biochemistry Department

The purpose of this project is to find a better electrolyte for safety uses in lithium battery. Ionic liquids is a salt in liquid state. It possesses unique combination of properties such as low vapor pressor, melting point and good salvation, high ionic conductivities. Electrolyte made from combining ILs and organic solvent can reduce the risk of explosion and energy loss. Research on these electrolyte can provide a better insight for develop a more efficient electrolyte system for long… Show more The purpose of this project is to find a better electrolyte for safety uses in lithium battery. Ionic liquids is a salt in liquid state. It possesses unique combination of properties such as low vapor pressor, melting point and good salvation, high ionic conductivities. Electrolyte made from combining ILs and organic solvent can reduce the risk of explosion and energy loss. Research on these electrolyte can provide a better insight for develop a more efficient electrolyte system for long lasting battery. We studied those characteristics by changing the solute structure, concentration and solution temperature to examine the ionization and solvation of the compound. Show less

Drop In Tutor, Chemistry And Biochemistry Department

Rowan University is a public research institution with approximately 16,000 students. The Department of Chemistry and Biochemistry currently serves over 850 biology majors. My responsibility is communicating with the faculty and staffs regarding course need, assisting the laboratory technician to prepare materials for Chemistry laboratory classes, cleaning and maintaining a safe environment for staffs and students.

Rowan University At Camden

Computer Lab, Rowan University At Camden

Working with computer is one of necessary part of learning in college. I assisted students with computer and printing issues in computer lab. I also helped maintaining and delivering technical equipments to provide a sufficient resource for learning environment.

Master Of Science - Ms, Pharmacology And Physiology

Bachelor Of Science (B.S.), Biochemistry

Activities and Societies: Rowan University at Camden Alliance of Student Activities (RU CASA), American Chemistry Society Club, Breast.