Anthony Perrier Email & Phone Number

Wilmington, Massachusetts, Us

Manage and coordinate studies in GLP conditions in a leader toxicology CRO for pharmaceutical, agrochemical and chemical industries- Study plans writing, management of the in-life phase, results analysis and report writing- Coordination of the different internal and external specialists needed for the in vivo study successfull progress- Inform sponsors on-time about study events and results- AWB member

Suresnes, Fr

Inform research project teams about off-target and on-targets risks of compounds (oncology, neurology, metabolism):- Molecule binding profile management- Research studies monitoring- In silico Virtual Assay tool management

Suresnes, Fr

Cell model development for the prediction of clinical toxicity, screening of new chemical entities (oncology, cardiology, neurology, diabetis):- Preclinical protocol writing, study management (budget, timelines)- Data analysis and interpretation (cardiotoxicity, myotoxicity using phenotypic analysis, behavioural neurotoxicity on zebrafish, genotoxicity using flow cytometry), research and screening report writing.- TSA (Target Safety Assessments) analysis involvement and mitigation plan proposal- Internal and external results presentation - Technical team operational management - Litterature monitoring (cardiotoxicity, myotoxicity, cell models, in vitro methods for toxicity evaluation…)

Suresnes, Fr

Medico-scientific follow-up of preclinical and clinical studies in pharmacology (rheumatology, immuno-inflammation)- Translational research : link between preclinical research and clinical development (biomarker identification, clinical data interpretation)- Clinical protocol and regulatory document writing - Verification of data consistancy (raw data, statistics) and interpretation- Internal and external results presentation- Evaluation of new therapeutic target scientific relevance (auto-inflammation, auto-immunity)- Litterature monitoring (physiopathology of different rheumatologic diseases, biomarkers, immunology, inflammation, competitive intelligence...)

Suresnes, Fr

Management of externalized preclinical pharmacology studies (rheumatology):- Preclinical protocol writing (in vivo, in vitro), study management (budget, timelines)- Verification of data consistency (raw data, statistics), interpretation, research report writing- Internal result presentation- Litterature monitoring (osteocytes, osteoblasts, osteoclasts, bone matrix, competitive intelligence…)

Paris, 13, Fr

PROJECT: Osteoblasts and their physico-chimical environment: matrix mineral content and micro-vibration effectsThis work showed that the bone cell extracellular matrix management towards a physiologic matrix was of first importance to understand bone cell response to mechanical stimulation (eg. osteoporosis treatment).The effect of Strontium ranelate, an anti-osteoporotic molecule was studied on osteoblasts in these physiological conditions.- Project management- Trainee management- Technical skills (cell and molecular biology, biomaterials)- International communications (posters, orlas, publications)- Litterature monitoring (osteocytes, osteoblasts, osteoclastes, cell mechanics, mechanical strains...)

Paris, 13, Fr

SUBJECT: Mechanical strain and leptin effects on human bone tissue (ex vivo)This work showed that, cultured in a bioreactor, human bone tissue remodeling was stimulated by mechanical strains and leptin. - Oral and written national communications - Technical skills (ex vivo bone tissue culture, Zetos mechanical strain device, immuno-histo-chemistery, enzymatic assays)- Litterature monitoring (ex vivo culture, mechanical strains, osteoblasts, osteoclasts)

Doctorat En Biologie Moléculaire Et Cellulaire, Tissu Osseux

Master Recherche Physiologie Intégrée En Conditions Extrêmes

Deug, Licence, Maîtrise, Biologie Cellulaire Et Physiologie

Experimentation Animale Niveau Concepteur-Réalisateur-Primates

Expérimentation Animale Niveau Concepteur-Réalisateur-Carnivores

Expérimentation Animale Niveau Concepteur-Réalisateur-Rongeurs-Lagomorphes

Baccalauréat, Spécialité Svt