Anthony Silver Email & Phone Number

Morrisville, North Carolina, United States

• Provided first line client support relating to Preclinical data collection and analysis for Provantis and Notocord software suites adhering to defined response and resolution timelines. • Received training and became certified to conduct SQL based queries for client Direct Database Updates• Provided client advocacy and support for NTP and several other assigned accounts meeting goals for client engagement and satisfaction ratings. • Provided client assistance in areas of Provantis… Show more • Provided first line client support relating to Preclinical data collection and analysis for Provantis and Notocord software suites adhering to defined response and resolution timelines. • Received training and became certified to conduct SQL based queries for client Direct Database Updates• Provided client advocacy and support for NTP and several other assigned accounts meeting goals for client engagement and satisfaction ratings. • Provided client assistance in areas of Provantis T&S templates and table generation • Served as Quality Assurance Internal Auditor assessing Instem processes against ISO9001 industry standards. • Served as advisor for clients and Instem’s interests in the field of behavioral and Safety Pharmacology. Show less

·Promoted to conduct and oversee GLP experimental procedures assessing respiratory and cardiovascular function in conscious rats, dogs and non-human primates. ·Met or beat 100% of deadlines in fast-paced environment. Consistently ran concurrent studies (independently) while guiding others in methodologies for their studies. ·Served as Study Monitor for Preclinical Safety Pharmacology respiratory, cardiovascular and CNS CRO studies, consistently meeting tight time… Show more ·Promoted to conduct and oversee GLP experimental procedures assessing respiratory and cardiovascular function in conscious rats, dogs and non-human primates. ·Met or beat 100% of deadlines in fast-paced environment. Consistently ran concurrent studies (independently) while guiding others in methodologies for their studies. ·Served as Study Monitor for Preclinical Safety Pharmacology respiratory, cardiovascular and CNS CRO studies, consistently meeting tight time constraints.·Served on departmental committees subsequently being selected as chairperson for the GLP committee responsible for ensuring FDA regulatory compliance in local and global relevance. ·Mentored and certified departmental associates in aspects of preclinical safety assessment in a GLP environment. Show less

·Using sterile surgical procedures, implanted vascular access catheters, renal flow probes and telemetry transmitters in rats, dogs and non-human primates. Routinely assessed and instituted process improvement.·Trained and certified scientists in dosing and blood sampling in mice, rat, dog and non-human primates by various routes.·Gained experience in ambulatory infusion methodology applied in the assessment of renal clearance in conscious unrestrained dogs.·Exhibited expertise in… Show more ·Using sterile surgical procedures, implanted vascular access catheters, renal flow probes and telemetry transmitters in rats, dogs and non-human primates. Routinely assessed and instituted process improvement.·Trained and certified scientists in dosing and blood sampling in mice, rat, dog and non-human primates by various routes.·Gained experience in ambulatory infusion methodology applied in the assessment of renal clearance in conscious unrestrained dogs.·Exhibited expertise in utilizing the proprietary electronic data collection software and hardware.·Developed proficiency in maintenance and use of access ports in rats, dogs and monkeys. Show less

·Conducted RNA probe labeling and dot blot hybridization.·Performed RNA tissue extraction, RNA cell culture extraction.·Prepared northern gels and RNA quantification techniques.·Utilized phosphoimager to aid in quantification analysis.

·Conducted surgical and experimental procedures to assess renal and cardiovascular function in conscious and anesthetized rats and dogs by various administration routes.·Gained experience in isolated perfused heart preparation.·Performed in vitro aortic ring procedure in the rat and rabbit.

·Assessed accumulation of organic anion and cations in renal cortical slices in the dog, rabbit, rat and mouse ·Assessed effects of in vitro and in vivo renal ischemia in renal cortical slices·Determined assessment of nephrotoxicity and hepatotoxicity utilizing radioisotope and visual spectrometric assays· Involved with the conduct of micronucleus test, dominant lethal assay and heritable translocation assay procedures in the rat, mouse and hamster·Maintained and assessed… Show more ·Assessed accumulation of organic anion and cations in renal cortical slices in the dog, rabbit, rat and mouse ·Assessed effects of in vitro and in vivo renal ischemia in renal cortical slices·Determined assessment of nephrotoxicity and hepatotoxicity utilizing radioisotope and visual spectrometric assays· Involved with the conduct of micronucleus test, dominant lethal assay and heritable translocation assay procedures in the rat, mouse and hamster·Maintained and assessed mutagenicity in mouse lymphoma cell cultures·Conducted CNS behavioral assessments for determining teratological effects Show less