Head of Chemistry and Bioconjugation, HSE Manager, Bracco SA, Geneva, Switzerland• Manage chemistry activities (5 members), set a new peptides and bioconjugation lab. overseeing the R&D of new chemical compounds and formulation, developing and implementing effective proof of concepts, creating and executing strategic plans, and providing mentorship to junior scientists.• R&D Manager for early and late-stage projects (clinical Phase III) with multidisciplinary teams: Chemistry, Biology, Physics, Formulation, Analytics, in-vitro & in-vivo activities, Quality, Legal, Business and Procurement departmentso Lead and organize the design and evaluation of innovative molecules for clinical studies o Ensure planning and execution of key projects (Drug/Gene delivery)o Ensure level of quality needed for future clinical evaluationo Recommend and contribute to the prioritization of the Research Portfolioo Contribute to the management of the global Research Budgeto HSE site manager, referent for authoritieso Peptides, small molecules, phospholipid, click-chemistry, gene delivery, bioconjugationBiomolecular-ligand research for Contrast Enhanced Ultrasound and Optical Imaging purposes

• Perform scientific due diligence on innovative technologies, develop business cases (CoG, P&L, DCF, NPV), scout and screen for portfolio opportunities, map and profile potential biotech/pharma partners, supported Serie A funding with VCs’ for a Gene Delivery Biotech, $65M. Analyse market trends, needs and assess opportunities and risks• Support the R&D organization to establish impactful research collaborations, contracts with external parties (start-ups, Universities). Congress presentations• Develop cutting-edge technologies within the Chemistry laboratory from early discovery to late phases development, with API manufacture, CMC, regulatory dossiers (IND, IMPD), for peptides, monoclonal antibodies, lipid nanoparticles, Bioconjugates, Gene delivery vectors, fluorescent imaging agents, use of Ultrasounds (Diagnostic/Therapeutic) in the fields of Oncology, Brain disorders• Drive cross-functional R&D projects and strategic outsourcing with technology transfer (CMO/CRO), process optimization, GMP preparation, and validation. Ensure evaluation, planning, resources engagement, and financial execution.

Senior Chemist (GMP) Almac Sciences, Craigavon, Northern Ireland and Elvingston, Scotland, UKo Technical Leader for GMP Projects (R&D, scale-up, downstream process for API)o Production of pharmaceuticals peptides and organic compounds (200K-10M CHF)o Liaise with peptide/protein group on technology transfer (discovery, innovation)o Coach and train peers (peptide chemistry, GMP rules…)o Prepare written protocols (CMC, SOP, MD, PD …) o Liaise with multifunctional teams (Manufacturing, Distribution, Stores, BD, QA, QC …)o Liaise with customers for quoting, project leader, preparation of aggregate reportsCommunicate with customers on technical issues, Prepare Quote for projects, Project leader

Design and synthesis of simplified analogues of liposidomycins (natural inhibitor) and preliminary biological evaluation (heterocycles and oligonucleotides chemistry)Lead PhD students and manage a European project EUR-INTAFAR (15 partners, University and business)

Design, synthesis and evaluation of catalytic peptide dendrimers as enzymes mimics.Methodology for the preparation of peptide dendrimers libraries on solid support for direct on-bead screening.Multistep synthesis of chiral Fluoro/Chromogenic substrates and building blocks.Develop delivery system for small molecules: vitamin B12, DNA…(binding, target identification)Manage research projects and lead students on a European projectCoordinate peptide projects with pharmaceutical industry