Ao Yang work email
- Valid
- Valid
- Valid
Ao Yang personal email
- Valid
Ao Yang phone numbers
• Over 14 years of pharmaceutical and biotech expertise with a focus on biochemistry, biophysics, and structural biology for drug discovery.• Extensive proficiency in utilizing diverse biochemical and biophysical techniques, such as NMR, SPR, BLI, ITC, TSA, FP, HTRF, HDX-MS, and native Mass Spec.• Specialized in protein science and structural biology, demonstrating proficiency across various target classes, including kinases, GTPases, GPCRs, and transcription factors. Successfully delivered over 250 X-ray or Cryo-EM structures.• A seasoned leader with over 10 years of experience in team management and CRO oversight.• Accomplished the delivery of 5 drug candidates from early discovery to clinical development.
-
Director, Structural BiologyQuotient Therapeutics Sep 2024 - Present -
Consultant On Drug DiscoveryIkena Oncology Apr 2024 - Sep 2024Boston, Massachusetts, Us -
Director, Biomolecular SciencesIkena Oncology Jun 2023 - Apr 2024Boston, Massachusetts, Us• Spearheaded chemical matter discovery initiatives at CRO for emerging pipeline targets, including 2 MAPK pathway mutants and 2 protein complexes. Oversaw the entire process, from target protein design and production to assay development, library screening, hit validation, and structure determination. • Provided comprehensive oversight of day-to-day research activities involving both the in-house team and CRO FTEs for Ikena's Lead Optimization programs. The focus was to guarantee the punctual delivery of biochemical and biophysical readouts obtained through diverse assays. Ensured the timely generation of key compound-target structures playing a pivotal role in steering the Structure-Activity Relationship (SAR) process for advancing the chemistry. • Fostered collaboration among cross-functional teams spanning medicinal and computational chemistry, cancer biology, in vivo pharmacology, and ADME. This collaborative effort resulted in the successful advancement of two drug candidates to the clinical stage:1) IK-930: (Target: TEAD1 selective, TEAD1-VGLL4 protein complex molecular glue, Phase I in 2023)2) IK-595: (Target: MEK-RAF complex, molecular glue, Phase I expected in 2024)• Cultivated external collaborations with academic institutions and Key Opinion Leaders (KOLs) to elevate the company's innovation capabilities and enhance its competitiveness.
-
Associate Director, Structural BiologyIkena Oncology Jan 2022 - Jun 2023Boston, Massachusetts, Us
-
Associate DirectorFlagship Pioneering Aug 2021 - Jan 2022Cambridge, Ma, Us• Led in establishing the "Programmogen" platform, with a focus on AI-based protein design for innovative VLP or non-VLP modalities featuring self-targeting epitopes. • Oversaw the in-house team in the production of self-targeting Programmogen, carried by bacteriophage VLPs (Qbeta, MS2, PP7, and PRR1), specifically designed for in vivo studies.• Led in in vitro assay development, both internally and at CROs. This involves analyzing the modulation of target serological levels and evaluating the abundance and affinity of self-targeting polyclonal antibodies derived from mouse serum samples, utilizing Biolayer Interferometry (BLI), Mesoscale Discovery (MSD), and Mass Spectrometry. -
Director, Structural Biology1Globe Health Institute Sep 2019 - Aug 2021Norwood, Ma, Us -
Peptide Screen Lead (Spotlight Biosciences)Life Biosciences Feb 2018 - Aug 2019Boston, Massachusetts, Us -
Director, Structural BiologyBoston Biomedical, Inc. Apr 2017 - Jan 2018
-
Associate Director, Structure BiologyBoston Biomedical, Inc. Dec 2015 - Apr 2017
-
Senior ScientistBoston Biomedical, Inc. Apr 2013 - Nov 2015
-
Postdoctoral ScientistPfizer Jan 2011 - Apr 2013New York, New York, Us -
Postdoctoral Research FellowUniversité De Montréal Oct 2006 - Dec 2010Montréal, Qc, Ca
Ao Yang Skills
Ao Yang Education Details
-
Pierre And Marie Curie UniversityMolecular Biophysics -
Pierre And Marie Curie UniversityMolecular Biophysics
-
Tsinghua UniversityBiological Sciences And Biotechniques
Frequently Asked Questions about Ao Yang
What company does Ao Yang work for?
Ao Yang works for Quotient Therapeutics
What is Ao Yang's role at the current company?
Ao Yang's current role is Director, Structural Biology.
What is Ao Yang's email address?
Ao Yang's email address is ay****@****cal.com
What is Ao Yang's direct phone number?
Ao Yang's direct phone number is +161767*****
What schools did Ao Yang attend?
Ao Yang attended Pierre And Marie Curie University, Pierre And Marie Curie University, Tsinghua University.
What skills is Ao Yang known for?
Ao Yang has skills like Nmr, Protein Expression, Protein Chemistry, Protein Purification, Drug Discovery, Biophysics, Structural Biology, X Ray Crystallography, Spr, Itc, Biochemistry, Mass Spectrometry.
Free Chrome Extension
Find emails, phones & company data instantly
Aero Online
Your AI prospecting assistant
Select data to include:
0 records × $0.02 per record
Download 750 million emails and 100 million phone numbers
Access emails and phone numbers of over 750 million business users. Instantly download verified profiles using 20+ filters, including location, job title, company, function, and industry.
Start your free trial