Ashley Schloss, Phd Email & Phone Number

New York, New York, United States

New York, United States

New York, New York, United States

Greater New York City Area

Greater New York City Area

New Haven, Ct

Thesis research in the laboratory of Dr. Lynne Regan. Thesis project focused on developing modular, protein-based hydrogel design for site-specific, targeted drug delivery.Mentored two visiting graduate scholars and one summer undergraduate student.Established a clinical collaboration with the Day Laboratory at the University College London.PresentationsA. Schloss, A. Omolu, R. Day and L. Regan. (2014). Protein-based hydrogels for targeted drug delivery The Protein Society; San Diego, CA; Poster presentation.A. Schloss and L. Regan. (2013). Design of 1D protein chains to fold into Eulerian 3D nanoparticles. The Protein Society; Boston, MA; Poster presentation.

Greater New York City Area

Investigated the potential use of a label-free detection assay in a high-throughput screening environment. Used optical biosensor technology to characterize the small molecule inhibition of two receptors involved in metabolic disease and cardiovascular disease.PresentationA. Schloss, J. Watson, D. Harden and A. Alt. 2011. Label-free detection of second messenger activity. Bristol-Myers Squibb Summer Research Symposium; Wallingford, CT; Oral Presentation.

Greater Philadelphia Area

Worked in the laboratory of National Academy of Sciences member Dr. William DeGrado. Synthesized small cyclic peptides as potential HIV-1 entry inhibitors targeting the sulfotyrosine-binding site on the viral envelope glycoprotein GP120. This work resulted in a peer-reviewed publication and several regional and national presentations.PublicationJ. Rudick, M. Laasko, A. Schloss, and W. DeGrado. (2013) Template-constrained cyclic sulfopeptide HIV-1 entry inhibitors. Org Biomol Chem 41, 7096-100Presentations A. Schloss, J. Rudick, and W. DeGrado. (2010) Rationally designed cyclic sulfopeptides for HIV-1 entry inhibition. 10th Annual Biomedical Research Conference for Minority Students; Charlotte, NC; Poster Presentation.A. Schloss, J. Rudick, and W. DeGrado. (2010) Rationally designed cyclic sulfopeptides for HIV-1 entry inhibition. University of Pennsylvania SUIP Symposium; Philadelphia, PA; Poster Presentation.A.Schloss, J. Rudick, and W. DeGrado. (2010) Rationally designed cyclic sulfopeptides for HIV-1 entry inhibition. Leadership Alliance National Symposium; Newark, NJ; Platform Presentation.

Greater Philadelphia Area

Completed undergraduate research in the laboratory of Dr. Jacqueline Tanaka. Used patch-clamp electrophysiology and molecular biology to investigate the structure and function of the cyclic nucleotide-gated ion channels of the visual system and channel mutants that cause achromatopsia or complete color blindness.PresentationA. Schloss, N. Tanaka, and J. Tanaka. 2010. Does the loss of an interaction between the S2 and S4 domains of a CNG channel cause complete colorblindness in dogs? Thomas Jefferson University Chapter Sigma Xi Student Research Day; Philadelphia, PA; Poster Presentation.

Doctor Of Philosophy (Phd), Molecular Biophysics And Biochemistry

Activities and Societies: Graduate Fellow for the Office for Diversity and Equal Opportunity, Protein Society Member, Biophysics Training.

Bachelor Of Science (B.S.), Chemistry

Activities and Societies: Minority Access to Research Careers Fellow, Resident Assistant (2 years), Math Tutor at the Math and Science.