Senior Process Scientist at STA Pharmaceutical, API development and manufacturing division of WuXi AppTec, San Diego, Ca, USA. Hands on research and scale up that includes process development and manufacturing solutions for small molecule active pharmaceutical ingredients (APIs) and advanced intermediates from preclinical to commercial which shortens the time to market and lowers the cost of drug development. Senior team member from San Diego, USA, for the Chinese CMO who received global regulatory approvals to produce NCE APIs and GMP intermediates and as a global leader in process R&D that offers a wide range of services. My current role as a senior process scientist is to coordinate efforts that includes synthetic route development, process development and optimization, research and scale up, in addition to assisting with proposals and reports as needed.

. Understanding and working with the company's various customer projects consisting of Aseptic Liquid, Powder, and Lyophilization Fill and Finish, Nano-emulsions, Homogenization, Microfluidization, Topicals and Creams, Labeling, Kitting, and Packaging, Storage and Distribution, Non-Aseptic Liquid, Powder, and Lyophilization Fill and Finish.Responsible for the internal and external customer service associated with assigned projects. Work closely with senior management to address key technical aspects of the projects and ensure that the needs from both our internal and external clients are met on time and on targetDetailed project planning, establish timelines and work closely with the project coordinators and operators.

Process research, route scouting, scale up and development of drug substances. Identify, analyze and determine fate of Impurities in active pharmaceutical ingredients (APIs) and final products.

Principal Scientist, Chemical Development.Duties include process research, scale up and development. Polymorph investigation and reference standard preparation.

• Develop safe, efficient and easily scalable processes for producing active pharmaceutical ingredients (APIs). • Process research and development and scale-up, documentation including master batch production records and SOPs. • Manage and coordinate activities for process scale-up to kilo-lab, to ensure safe and CGMP-compliant execution of API manufacturing processes. • Train staff in protocols and techniques relevant to chemical process R&D and operations. • Provide technical and trouble-shooting support for process from discovery to scale up. • Collate and present results in various forms, such as monthly reports, technical reports, and oral presentations. • Exemplify Arena’s environmental, health and safety guidelines.

• Developmental assignment from chemical development to medicinal chemistry group. • Collate and present results in various forms, such as monthly reports, technical reports, and oral presentations. • Working closely with the medicinal chemistry group to scale up compounds from milligram to gram scale for screening, toxicological and dose escalation studies.• Working together with the scale up team to transfer processes from gram scale to kilo scale and also assist the team for CGMP scale as needed.

Process research and development and scale-up, documentation including master batch production records and SOPs. • Manage and coordinate activities for process scale-up to kilo-lab, to ensure safe and CGMP-compliant execution of API manufacturing processes. • Literature searches and scouting for new routes for improved process and scale up of current procedures from early research programs. • Collate and present results in monthly reports, electronic notebook records and oral presentations

As a team leader work involved writing proposals, project planning, custom synthesis, developing chemical processes for research and scale-up. Supervised senior chemists (Ph.D.) and research associates (B.S.) working on the projects. Business development: Customer contacts and helping with marketing and sales.

As a team leader work involved writing proposals, project planning, developing chemical processes for research and scale-up and carrying out synthesis of preclinical pharmaceutical intermediates and final products following cGMP guidelines. Supervise senior chemists (Ph.D.) and research associates (B.S.) working on the projects. Business development: Customer contacts and helping with marketing and sales by attending trade shows, help setting up booths and presenting to clients.

Conducted organic synthesis to develop chemical processes for scale-up and troubleshooting process problems. Analyzed, evaluated, and planned methods of approach (reviewed literature, patents, and current technology) and organized means to achieve solutions to problems. Improved and modified processes to be cost-competitive and amenable to scale-up.

Discovery research, responsible for the synthesis and design of novel MR (Magnetic Resonance) and CT (Computer-Tomographic) imaging agents. Received a patent for work on “Fluorinated Triglycerides” as liver MRI agents Received a patent for work on a novel class of “Calixarene” compounds as CT and MRI agentsHelped legal department with writing and defending patents

Responsible for the design and synthesis of medicinal agents for U.S. Army, Walter Reed Research Institute. Acquired knowledge of CGMP procedures. Synthesized antimalarials, nerve agent and cyanide antidotes, and antiviral compounds

Conducted basic research involving synthesis of agricultural and pharmaceutical chemicals.Significant contributions in the highly competitive herbicide area with a patent issued in 1987.Strong background in heterocyclic chemistry (refer Patent. US 4,678,499-Herbicidal sulfonamides) Supervise research associates (B.S.) working on the projects.