Asma E. Email & Phone Number

Hampton, Nj, Us

Wilmington, Massachusetts, Us

Watertown, Ma, Us

Tokyo, Jp, Jp

I designed, developed, and implemented cutting-edge scientific projects to propel advancements in biotechnology, clinical diagnostics, and pharmaceutical assays, strictly adhering to Study Protocols and GLP/CAP/CLIA regulations. My role encompassed preparing comprehensive SOPs, validation protocols, and reports, while also managing and mentoring junior scientists and research associates. I led and executed complex projects involving diverse technologies, organized and delivered presentations at client meetings, and developed, qualified, and validated a range of assays including PK, ADA/immunogenicity, PD, and Histology (ISH and IHC). Additionally, I developed Luminex-based inflammatory cytokine assays and created innovative cell-based assays.

Research Fellow at Integrative Physiology and Metabolism, Joslin Diabetes Center.I focused to explore the early signatures of insulin resistance and to understand the complex pathophysiology of diabetes and to identify and target specific mechanisms to prevent T2D in at-risk individuals.

Boston, Ma, Us

At Department of Surgery, Division of Vascular and Endovascular Surgery at Beth Israel Deaconess Medical Center, I studied the role of neuropathy and vascular disease in diabetic heart and explore the effect of neuropeptides such as NPY, CGRP, SP and many others.

Medford, Massachusetts, Us

As a graduate student at Vascular Biology Laboratory, Jean Mayer USDA HNRCA at Tufts University.I focused on role of dietary antioxidants, lipids and oxidative stress on molecular mechanisms of immune/endothelial cells interaction in angiogenesis and obesity.Detail:This research project mainly focused on the effect of the consumption of dietary antioxidants curcumin on angiogenesis and obesity. Curcumin is an active ingredient in turmeric, a common cooking spice. I diligently started to investigate the effects of curcumin on obesity; in vitro cell culture system and an in vivo animal model of diet-induced obesity. In that study, in addition to carefully investigating the effect of curcumin supplementation on angiogenesis, I meticulously studied the effect of curcumin on adipocytes differentiation, apoptosis and gene expression of several key enzymes including AMPK, ACC, CPT-1 and GPAT-1 and transcription factors (PPAR-γ and C/EBP-α) that are involved in energy and lipid metabolism in cell culture system. Then I tested the effect of curcumin on body weight gain and adiposity in mice fed high fat diet. Further, I measured the effect of curcumin on adipose tissue vascularity along with expression of vascular endothelial growth factor (VEGF) and its receptor (VEGFR-2), liver steatosis and expression of genes and transcription factors that are involved in energy/lipid metabolism.Publications:http://www.fasebj.org/cgi/content/meeting_abstract/22/1_MeetingAbstracts/158.4?sid=7d1a1ce6- http://www.fasebj.org/cgi/content/meeting_abstract/21/6/A1089http://pubsearch.arsnet.usda.gov/search?q=asma+ejaz&btnG.x=-390&btnG.y=-163&btnG=Go%21&btnG=Go%21&filter=0&as_sitesearch=ars.usda.gov&ie=&output=xml_no_dtd&client=ars_frontend&lr=&proxystylesheet=ars_frontend&oe=