Atanu Paul Email & Phone Number

Cambridge, Massachusetts, United States

Boston, Massachusetts, United States

Watertown, Massachusetts, United States

1) Lead biologist for a new oncology target in solid tumors to devise and implement cellular and biochemical assays to understand the mechanism of action of heterobifunctional PROTAC.2) A key contributor to the development and implementation of high throughput cell-based assays for hit finding and hit-to-lead optimization both internally and CROs.3).

Watertown, Massachusetts, United States

1) Lead biologist for an exploratory project targeting membrane protein for targeted protein degradation using heterobifunctional PROTACs.2) Developed in vitro assays for screening PROTAC molecules.3) Analyzed, troubleshoot, and present data internally in cross-functional team meetings to facilitate go/no go decisions.4) Actively managed CROs.

Watertown, Massachusetts, United States

1) Performed Mechanism of Action analysis for heterobifunctional PROTAC (IRAKIMiD- KT-413) and Molecular Glues (Imids) to understand differential drug mechanisms of action in heme malignancies.2) Compared superior phenotypic response in targeting both IRAK4 and Imid substrates with KT-413 than Imid-based molecular glues by cell-based and biochemical.

Cambridge, MA

1) Involved in early discovery biology projects aiming to identify and validate novel gene(s) involved in cancer cell signaling pathways.2) Using Genome-wide unbiased CRISPR screen, identified a transmembrane protein, KIRREL1, in modulating the Hippo-YAP pathway at the plasma membrane (Paul et al, Nature Communication, 2022)3) Performed biochemical and.

Houston, TX

Dissertation Title: Phosphorylation And Ubiquitin Modification At DNA Damage Sites In Response To Double-Strand Breaks1) Uncovered the role of BRCA1-A complex protein - Abraxas in maintaining genome stability and tumor suppression (Cell Reports 2014).2) Identified and characterized the role of DNA damage-dependent Abraxas phosphorylation in the.

El Paso

Thesis Title: A specific regulatory role for SGTα on the maturation and activation of steroid hormone receptorsCharacterized a newly identified Hsp90-Hsp70-associated cochaperone SGTA in regulating specific steroid hormone receptor complex and identified SGTA’s role in inhibiting FKBP52-mediated potentiation of receptor activity (JBC 2014).

Doctor Of Philosophy (Ph.D.), Biochemistry And Molecular Cell Biology, 3.65

Master’S Degree, Biochemistry And Molecular Biology, 3.92

Doctor Of Veterinary Medicine (Dvm), Veterinary Medicine, 3.93