A result-oriented professional with a fruitful total of 9.4 years of experience in the field of R&D from which 7.8 years in the field of Drug metabolisms and Pharmacokinetics. Currently working as Specialist-DMPK at Aurigene Pharmaceutical Services Limited, Bangalore from Jan 2022. I have done my PhD under the supervision of Dr. Jiaur R. Gayen, Principal Scientist,CSIR-Central Drug Research Institute, Lucknow-226031, India.I have quite a knowledge of drug-drug interaction, herb-drug interaction, and preclinical pharmacokinetics of NCEs. Bioanalytical and analytical method development using HPLC and LC-MS/MS for quantification of NCEs and drugs. Preclinical xenobiotic/drug metabolisms and pharmacokinetics in pharmaceuticals discovery and development program. I serve as the bioanalyst and pharmacokinetics on various drug discovery teams for cancer, tuberculosis, CNS, ASTHI, phytopharmaceutical, and neutraceutical projects. Hands-on with different instruments like AB SCIEX 5500 and API-QTRAP 4000 LC-MS/MS, HPLC (Shimadzu and Waters), UV-Spectrophotometer (Hitachi), Nanodrop (Thermo Scientific), High –Pressure homogenizer.....Skills & Abilities• Research and Development• Well-versed in CYP inhibition study, microsomal stability, hepatocytes stability, protein binding, S9 stability (phase I and II metabolic stability), peak purity, LogP, LogD, ChromLogD, HTS, pH-dependent solubility, SGF/SIG, permeability (SPIP), plasma stability, blood plasma portioning studies.• Quite expert in handling laboratory animals (mice/rat/hamster/rabbits), and dosage administration (oral, i.v, i.p, i.m, and s.c routes).• Acquired proficiency in drug metabolism and in-vivo preclinical pharmacokinetics (oral/iv/im/sc/ip), drug-drug interactions, herb-drug interactions, dose proportionality studies, gender differences, species comparisons, and tissue distribution studies.• Familiar with bio-sample preparation techniques like protein precipitation, liquid-liquid extraction and solid-phase extraction. Hands-on bioanalytical and analytical method development using HPLC (Shimadzu and Waters) and LC-MS/MS (ABSciex 4000 QTRAP & 5500 QTRAP, and Thermo Scientific TSQ Altis™) for quantification of NCE’s, phytoconstituents, drugs, metabolite or biomarkers in different biological matrices.• Handling of an automated liquid handler (Biomek i7, Beckman Coulter).• Review of literature from various search engines.• Pheonix 6.3 WinNonlin (Pharsight Corporation, USA), Analyst 1.6, GraphPad Prism 9.5, Mendeley, MS Office, and Endnote 7 softwares.