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Aude Chiot, Ph.D Email & Phone Number
Post Doctoral Fellow - Bahareh Ajami's lab
at
Oregon Health & Science University
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✓ Verified July 2026
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Current company
Role
Post Doctoral Fellow - Bahareh Ajami's lab
Location
Paris, ÎLe-De-France, France
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Aude Chiot, Ph.D is listed as Post Doctoral Fellow - Bahareh Ajami's lab at Oregon Health & Science University, based in Paris, ÎLe-De-France, France. AeroLeads shows a matched LinkedIn profile for Aude Chiot, Ph.D.
Aude Chiot, Ph.D previously worked as Career Development Officer - OHSU Postdoc Society at Oregon Health & Science University and Postdoctoral Fellow - Séverine Boillée's lab at Institut Du Cerveau – Paris Brain Institute. Aude Chiot, Ph.D holds Doctor Of Philosophy - Phd, Neuroscience from Sorbonne University.
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Oregon Health & Science University
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Profile bio
About Aude Chiot, Ph.D
👩🏻⚕️As a postdoctoral fellow at Oregon Health & Science University, I am passionate about understanding how our immune system works and studying the connections between the nervous and immune systems. I have more 10+ years of experience in conducting and leading innovative research projects in this field.🔬I apply a range of cutting-edge techniques, such as spatial and single-cell transcriptomics, fate mapping, iPSCs cell differentiation, Crispr genome editing, and human tissue analysis, to unravel the diversity and functions of microglia and macrophages in both health and disease. One of my notable achievements was co-leading a study that revealed the potential of integrin alpha-5 as a target for ALS therapy, in collaboration with Stanford University, the Mayo Clinic, and Pasithea Therapeutics. 💊 My goal: translating fundamental research findings into tangible and promising treatments using the power of our immune system.
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10 roles · 19 years
Aude Chiot, Ph.D work experience
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Career Development Officer - Ohsu Postdoc Society
Current
Apr 2022 - Present
Post Doctoral Fellow - Bahareh Ajami'S Lab
Current👩🏻⚕️ Expanding my knowledge on macrophage biology and Neuroinflammatory processes in health and neurodegenerative disorders, such as ALS. 🔬Spatial and single-cell transcriptomics, transgenic mouse models and human tissue analysis, imaging, iPSCs cell culture, Crispr genome editing and bioinformatic analysis.🔍 Co-led a study investigating the role of the integrin alpha-5 in ALS disease, that is now being developed as a monoclonal antibody treatment for ALS (in collaboration with Stanford University, the Mayo Clinic, and Pasithea Therapeutics).Our findings showed alpha5 intern as a driver of inflammation and revealed its expression by peripheral nerve macrophages and spinal cord microglial cells in ALS mice and post-mortem tissue from ALS patients.📖 https://www.pnas.org/doi/10.1073/pnas.2306731120📣 https://alsnewstoday.com/news/als-therapy-target-integrin-that-spurs-immune-cells-to-eat-neurons/🔍 I am currently co-leading a study focusing on enhancing our comprehension of macrophage biology in the inner ear. (Collaboration USA-Germany). This project aims to establish a robust foundation for future investigations into the involvement of macrophages in various health conditions, such as noise-induced hearing loss. This study is currently under review.🔍 Additionally, I am leading a project aimed at gaining deeper insights into immune cells in ALS disease. In ALS pathophysiology, inflammation driven by microglia and macrophages plays a pivotal role. Recognizing their plasticity, the project aims to modulate these adaptive cells. Through a comparative analysis of microglial cell profiles in the degenerating spinal cord and the preserved oculomotor neuron nucleus, the goal is to pinpoint distinct transcriptomic and proteomic profiles linked to either neurodegeneration or the protection of motor neurons.
Mar 2020 - Present
Postdoctoral Fellow - Séverine Boillée'S Lab
Nov 2018 - Nov 2019
Phd Student - Séverine Boillée'S Lab
Institut Du Cerveau – Paris Brain Institute
🔍My main goal was to investigate the role of macrophages within the peripheral nervous system, particularly the sciatic nerve, in comparison to microglial cells in ALS disease, as they are easier to access for future therapies.Our comprehensive study showed that:- Macrophages exhibit a strong responses to the disease.- Monocyte-derived macrophages are crucial for the reactivity and activation of the sciatic nerve macrophages, but their contribution is minor in the spinal cord microglial cell population.- Macrophages in the nerve respond earlier to the disease than microglial cells, and display distinct transcriptomics changes. - Replacing macrophages the periphery with more trophic macrophages in an ALS mouse model led to a delayed symptomatic stage and increased survival. This effect was attributed not only to promoting protection in the peripheral nervous system but generating a neurotrophic response in the central nervous system, mediated by microglial cells.📖 https://www.nature.com/articles/s41593-020-00718-z📣 https://www.alzforum.org/news/research-news/can-muscle-macrophages-coax-spinal-cord-microglia-protect-neurons
Sep 2014 - Oct 2018
Theatre Employee (Confirmed) - Gaumont Opéra
2013 - 2015
~2 yrs
Theatre Employee (Confirmed) - Gaumont Alésia
2009 - 2013
~4 yrs
Theatre Employee (Junior) - Gaumont Alésia
2008 - 2009
~1 yr
Sales Assistant
Mar 2012 - Aug 2012
Au Pair
Jan 2008 - Aug 2008
4 education records
Aude Chiot, Ph.D education
Doctor Of Philosophy - Phd, Neuroscience
Master'S Degree, Integrative Biology And Physiology (Aging Biology)
Master Of Science - Ms, Cell/Cellular And Molecular Biology
Bachelor'S Degree, Life Science
FAQ
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What company does Aude Chiot, Ph.D work for?
Aude Chiot, Ph.D works for Oregon Health & Science University.
What is Aude Chiot, Ph.D's role at Oregon Health & Science University?
Aude Chiot, Ph.D is listed as Post Doctoral Fellow - Bahareh Ajami's lab at Oregon Health & Science University.
Where is Aude Chiot, Ph.D based?
Aude Chiot, Ph.D is based in Paris, ÎLe-De-France, France while working with Oregon Health & Science University.
What companies has Aude Chiot, Ph.D worked for?
Aude Chiot, Ph.D has worked for Oregon Health & Science University, Institut Du Cerveau – Paris Brain Institute, Gaumont, Le Bhv Marais, and Au Pair World.
How can I contact Aude Chiot, Ph.D?
You can use AeroLeads to view verified contact signals for Aude Chiot, Ph.D at Oregon Health & Science University, including work email, phone, and LinkedIn data when available.
What schools did Aude Chiot, Ph.D attend?
Aude Chiot, Ph.D holds Doctor Of Philosophy - Phd, Neuroscience from Sorbonne University.
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