Aurélia E Lewis Email and Phone Number

Proteins function in complex with not only proteins but also with other biomolecules. Such networks are essential to all biological functions and their alteration can often lead to disease.Our lab focuses on protein-phospholipid interaction networks and we analyse their composition, regulation as well as their functional roles. In addition, our goal is to understand how these networks are remodelled in healthy and pathological states where the phosphoinositide metabolic pathways are… Show more Proteins function in complex with not only proteins but also with other biomolecules. Such networks are essential to all biological functions and their alteration can often lead to disease.Our lab focuses on protein-phospholipid interaction networks and we analyse their composition, regulation as well as their functional roles. In addition, our goal is to understand how these networks are remodelled in healthy and pathological states where the phosphoinositide metabolic pathways are known to be altered (particularly in obesity, type 2 diabetes mellitus, cancer). Show less

Mass spectrometry-based proteomic investigation of nuclear phosphoinositide signaling

Molecular mechanisms of differentiation and tissue specific gene regulation: Integration of hormonal-dependent signal transduction and gene regulation

Signal transduction elucidation in cell cycle regulation and Ras-mediated apoptosis in thyrocytes