Austen Terwilliger, Ph.D. Email and Phone Number
Austen Terwilliger, Ph.D. work email
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Austen Terwilliger, Ph.D. personal email
Molecular microbiologist committed to combating the notorious ESKAPE pathogens and multi-drug resistance. I am developing technologies that evolve and purify bacteriophage (phage) to rapidly generate and formulate therapeutic cocktails. Co-founding the phage technology service center “TAILΦR” provides the opportunity to treat patients on a compassionate use basis
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Director Of Operations - Tailφr Service CenterBaylor College Of MedicineHouston, Tx, Us
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Director Of Operations - Tailφr Service CenterBaylor College Of Medicine Jan 2020 - PresentHouston, Texas AreaService center dedicated to addressing the antibiotic-resistance crisis and serving the most vulnerable patients.Developed and managed a sponsored research agreement budget of $197K that earned $63K for the Baylor College of Medicine.Coordinate center development, client projects, research, phage discovery, and patient cases amongst group members.Liaise between clinical, academic, and regulatory teams for compassionate use patient cases.Built collaborations with the Alkek Center for Metagenomics and Microbiome Research, the Center for Cell and Gene Therapy, and Houston Public Works to provide sequencing, safety/sterility, and environmental sampling services respectively.Implemented cloud-based documentation to instantly track projects, experiments, data, and inventories.
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Postdoctoral AssociateBaylor College Of Medicine Jan 2017 - Apr 2020Houston, TexasDiscovered lytic bacteriophages (phages) that target clinical isolates of ESKAPE pathogens.Formulated, characterized, and vetted therapeutic phage cocktails to treat E. cloacae and E. coli infections.Developing an expedited phage purification scheme designed to generate therapeutic-quality phage with generally-recognized-as-safe (GRAS) reagents.Co-inventor of the Tetrastat; a continuous-culture device that directs the evolution of phage to target selected bacterial strains.Employed the Tetrastat to generate de novo phage that target previously refractory strains of Extraintestinal Pathogenic E. coli (EXPEC) and P. aeruginosaCreated transporter and biosynthetic gene deletions to investigate link between branched-chain amino acid and iron acquisition systems in Bacillus anthracis Sterne.
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Graduate StudentBaylor College Of Medicine Aug 2011 - Jan 2017Houston, TexasCreated Blood Serum Mimic defined medium to identify a novel role for hemoglobin as a branched-chain amino acid source for Bacillus anthracis during amino acid starvation. Identified the InhA1 extracellular metalloprotease as necessary for hemoglobin proteolysis.Developed a transposon mutagenesis screen to discover genes involved in amino acid acquisition from hemoglobin in vitro.Identified a brnQ5 mutant, disrupting a putative branched-chain amino acid/sodium symporter, as attenuated in an inhalational model of murine anthrax.
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Research TechnicianUniversity Of Pittsburgh Oct 2009 - Jul 2011Pittsburgh, PennsylvaniaProvided direct support to graduate students, postdocs and principal investigator. Responsibilities included sample processing, data collection, experimental setup, and assisting on other projects/tasks as needed.Applied fluorescent live cell microscopy to image calcium storage and signaling in eukaryotic cell lines. Utilized whole cell patch-clamp to analyze ion transport of mutant mucolipin channels. -
Undergraduate Research AssistantUniversity Of Pittsburgh Jun 2008 - Apr 2009Pittsburgh, PennsylvaniaCreated a mutant self-splicing intron via site-directed mutagenesis, and generated cDNA products from in vitro splicing reactions.Assayed splicing efficiency through colorimetric ß-galactosidase screening.
Austen Terwilliger, Ph.D. Skills
Austen Terwilliger, Ph.D. Education Details
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Molecular Microbiology, Microbial Pathogenesis
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Biology/Biological Sciences, General
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Semester At SeaStudy Abroad Program
Frequently Asked Questions about Austen Terwilliger, Ph.D.
What company does Austen Terwilliger, Ph.D. work for?
Austen Terwilliger, Ph.D. works for Baylor College Of Medicine
What is Austen Terwilliger, Ph.D.'s role at the current company?
Austen Terwilliger, Ph.D.'s current role is Director of Operations - TAILΦR Service Center.
What is Austen Terwilliger, Ph.D.'s email address?
Austen Terwilliger, Ph.D.'s email address is au****@****bcm.edu
What schools did Austen Terwilliger, Ph.D. attend?
Austen Terwilliger, Ph.D. attended Baylor College Of Medicine, University Of Pittsburgh, Semester At Sea.
What skills is Austen Terwilliger, Ph.D. known for?
Austen Terwilliger, Ph.D. has skills like Science Communication, Microbial Pathogenesis, Biochemistry, Protein Purification, Cell Biology, Mouse Infection Models, Biosafety Level 3 Training, Site Directed Mutagenesis, Microscopy, Data Analysis, Research, Microsoft Office.
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