Alec Vallota-Eastman, Ph.D. Email & Phone Number

Irvine, Ca, Us

Moffett Field, California, Us

• Serve as liaison between scientists, engineers, and software developers, aligning goals for data processing and analysis workflows.• Guide the design of a multi-omics database, establishing metadata standards and computational tools for space bioscience research.• Process and analyze omics datasets (RNASeq, whole genome sequencing) using Python, R, and Linux pipelines to ensure quality and accuracy.• Represent GeneLab by presenting database capabilities at conferences, fostering collaborations and technical adoption.

Moffett Field, California, Us

• Partnered with 6 departments to standardize the BDME repository using Python scripts and AWS, improving accessibility for 300+ studies within 6 months.• Automated ingestion and quality control of 12 datasets per month using Python and R, streamlining -omics data processing and boosting research productivity.• Diagnosed assay curation challenges and co-developed scripts to automate template generation, reducing manual efforts by 40%.

Salt Lake City, Utah, Us

• Directed regulatory projects, including designing and validating a probe-based ddPCR assay for SARS-CoV-2 quantification, ensuring compliance with FDA guidelines and delivering results under tight deadlines.• Authored comprehensive protocols and regulatory submissions, spearheading a panel inclusivity validation study that ensured FDA compliance and shortened approval timelines by 20%.• Led a team of 4 research associates, implementing troubleshooting protocols for dPCR, ddPCR, and qPCR experiments, increasing assay reliability by 30% through rigorous optimization and quality control.

Moffett Field, California, Us

• Engineered an in-vivo pharmaceutical peptide secretion platform using synthetic biology techniques, reducing production timelines for space missions by 50% within 6 months.• Partnered with multidisciplinary teams to advance space bioscience research, authoring 1 first-author and 2 co-authored manuscripts, and presenting findings at a NASA conference to strengthen research collaborations.• Designed, constructed, and characterized 1,000+ plasmid constructs and 24 transgenic cell strains using CRISPR and flow cytometry, accelerating genetic modification pipelines by 40%.

Santa Barbara, Ca, Us

• Secured and managed a $1M Department of Defense grant, advancing two directed evolution projects on biofuel-producing photoenzymes, achieving measurable improvements in enzymatic efficiency.• Conducted genomic analysis of accelerated evolution in cyanobacteria, utilizing Python and R, leading to a first-author publication and bioengineering insights.• Co-authored a Nature Chemistry publication on directed evolution of radical photocyclases, enabling stereodivergent biocatalysis with applications in asymmetric radical chemistry.• Mentored and trained three professionals in molecular biology techniques and laboratory instrument calibration (e.g., Milli Q, GC-FID, Fluorometer).• Authored a cross-functional first-author publication on sequencing data analysis and protein evolution, showcasing collaborative research skills.• Supervised and trained 14 researchers across five interdisciplinary projects spanning molecular biology, bioinformatics, engineering, and protein purification, fostering team collaboration and mentorship.

Corvallis, Or, Us

• Contributed to the discovery of a novel protease inhibitor with pharmaceutical potential, resulting in a co-authored publication in Journal of Natural Products.• Published a thesis and peer-reviewed articles on phage marker gene sequencing and 16S taxonomy analysis, providing foundational insights for early drug discovery.• Created and optimized CRISPR/Cas mutagenesis protocols for zebrafish embryos, including designing sgRNA and constructing nine combinatorial dCas9 transcriptional activators.• Isolated and morphologically identified nine phages pathogenic to Clostridium beijerinckii, developing protocols using TEM imaging and presenting findings at a spring symposium.

Doctor Of Philosophy - Phd

Bachelor Of Science - Bs, Bioproducts & Bioinformatics, Minor In Chemistry

Bioengineering