Jim Beck Email and Phone Number

Joint appointment between Idaho National Lab and Boise State University to maintain and support the utilization of the Falcon supercomputer by research partners from all scientific disciplines.

Bioinformatics scientist focusing on: * In-silico on and off-target CRISPR assays, * Data integration for off-target assay library development* Proto-spacer Adjacent Motif (PAM) characterization pipelines* Alignment tools to capture Cas system specific editing characteristics* Predictive pipelines for new target spacer identification and profiling

Research in Molecular Biology: • Predicted the impact of mutations on the functional activity of RNA variants using custom machine learning pipelines implementing Autoencoders, LSTM, SVR, and Random Forest models from PyTorch and Scikit-Learn. • Developed custom Julia code for the high-throughput processing of deep mutational scanning libraries to characterize relative and epistatic measurements of activity of non-coding RNA variants.• Created software for the high-speed calling of RNA variants, increasing the read depth four-fold for in FASTQ file reads. • Developed a high-volume visualization processing of mutational variation related to structural significance for RNA variants. • Designed custom processing tools to select catalytically important parameters by fitting exponential decay functions to functional RNA activity observations. • Applied dimensionality reduction techniques on regulatory distal elements of Aquaporin genes within Artemisia tridentata. • Implemented a differential gene expression pipeline for Apolipoprotein E4 fragments to identify up and down regulated genes involved in Alzheimer’s disease.• Calculated stability values for reference gene primers used for qPCR amplification of telomeres in vertebrates.• Developed training materials and programs on the use of dimensionality reduction and high-performance computing resources, supercomputer clusters, Julia, Python, R and Bash scripting.

Graduate Teaching Assistant for Data Structures

A software development practice creating a physician performance software platform and specialized development analysis for neurosurgical service expansion.

A consultancy providing operational and physician integration services to physician groups, hospitals, and integrated health systems.

A professional consultancy providing operational and physician integration services to physician groups, hospitals, and integrated health systems.