Student Assistant
Current• Worked on exercises in mathematical modeling of cardiovascular physiology under the supervision of Professor Eleonora Grandi, PhD FHRS, including implementing my own Hodgkin-Huxley model in Matlab as well using the Grandi model to explore population modeling and linking genetic defects to cellular cardiac phenotypes by predicting arrythmogenic effects and sex-specific difference in arrhythmia susceptibility.• Presented preliminary research findings in a poster session at the E-Search… Show more • Worked on exercises in mathematical modeling of cardiovascular physiology under the supervision of Professor Eleonora Grandi, PhD FHRS, including implementing my own Hodgkin-Huxley model in Matlab as well using the Grandi model to explore population modeling and linking genetic defects to cellular cardiac phenotypes by predicting arrythmogenic effects and sex-specific difference in arrhythmia susceptibility.• Presented preliminary research findings in a poster session at the E-Search Research Presentation, highlighting key insights into the sex differences in early-after depolarizations susceptibility .• Expanded on initial exercises branching into my own project ahead of starting my PhD using a modified version of the O’Hara Rudy model tailored to female physiology in both single cell and cable configurations to investigate LongQT syndrome and the potential mechanisms behind known sex differences in arrhythmia susceptibility associated with mutations. Show less
