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Versatile, Hands-on, Persistent researcher skilled in biological product discovery and development. Chemical engineer with strong practical experience in fermentation, molecular and cellular biology, and immunology. Designed systems to evaluate and quantify clinically relevant cell therapy products, biofuel producing strains of bacteria, and growth medium for both bacterial and mammalian cell culture
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Senior Process Development Engineer IiCaribou Biosciences Oct 2022 - PresentBerkeley, Ca, Us
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Sr Process Development Engineer ICaribou Biosciences Oct 2021 - Oct 2022Berkeley, Ca, Us
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Process Development Engineer IiCaribou Biosciences Dec 2020 - Oct 2021Berkeley, Ca, Us
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Process Development Associate IiiEureka Therapeutics, Inc Aug 2020 - Dec 2020Emeryville, Ca, Us-Process development of clinical T cell therapy manufacturing -
Process Development Associate Ii In Clinical T Cell ManufacturingEureka Therapeutics, Inc Oct 2018 - Aug 2020Emeryville, Ca, UsI focus on technology transfer from the lab bench to early clinical production. This involves writing SOPs, qualifying assays, and process development of T cell manufacturing and viral vector production.
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Research Associate, R&D - Drug Discovery, Product DevelopmentNantbioscience, Llc May 2015 - Mar 2018I worked in Research and Development. I was responsible for validating the efficacy of new products in the drug discovery and product development pipelines. I used molecular biology techniques, searched relevant literature, designed experiments, and presented my results appropriately. Achievements:-Developed functional assays to evaluate cytotoxicity and binding of potential monoclonal antibodies, chimeric antigen receptors, cytokines, and engineered lymphocytesPrepared large batches of cell therapy product for pre-clinical evaluation and generated data for IND applications -Serum free, xeno free media development using factorial design-Flow cytometry to study phenotypical and activation markers, discover in-vitro assay targets, and to confirm product consistency between batches and across different manufacturing locations-Optimized protocols for cryopreservation and irradiation of clinical products-Performed mammalian cell culture using aseptic technique for tumor cell lines and primary cells-Maintained laboratory inventory, ordered lab reagents and consumables, evaluated new equipment and drafted SOPs
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Research AssociateEasel Biotech Mar 2012 - May 2015As a research associate for Easel, I provided support for the complete process of developing renewable biofuels and biochemicals from various feedstocks including corn stover, CO2, algae, nitrogen based waste products. I provided molecular biology support for genetic engineering of production strains of E. coli, bacillus, algae, ralstonia eutropha, alcaligenes eutropha, yeast, and others. I also provided support with process development and optimization. I used biological assays and analytical chemistry methods to evaluate the yield, titer, and productivity of engineered, production strains.Achievements:-Set up, maintained, and troubleshot over 100 biofuel, biochemical, and bioplastic fermentations-Characterized fermentation by-products using Gas Chromatography, High Pressure Liquid Chromatography, Elemental Analysis, and UV/Vis to measure alcohol content, perform colorimetric and kinetic enzyme assays, and estimate cell viability-Designed and implemented bench scale product purification unit operations including crystallization, distillation, continuous centrifugation, and tangential flow filtration-Performed microbiology laboratory tasks including PCR, DNA assembly, Protein Purification, Bradford Assays, Gel Electrophoresis, Pipetting, Titrating, Weighing, Centrifugation-Helped maintain laboratory inventory, patent database, and safely disposed of chemical waste-Helped company meet biofuel titer benchmarks set by Department of Energy ARPA-E program-Assisted company in receiving Government and Private funding by writing and reviewing grants-Created and organized lab protocols for new laboratory experiments and procedures
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Manufacturing Engineering InternNutrilite Jun 2011 - Sep 2011Fortaleza, Ceará, BrIdentify bottleneck in softgel manufacturing and propose solutions to increase throughput. Created a test plan and validation for a portable handler unit to reduce the drying times of softgels. -
Undergraduate Research AssistantUcla Jun 2010 - Jun 2011Los Angeles, Ca, UsWorked in the metabolic engineering laboratory. Project involved altering bacillus bacteria to convert pyruvate to longer chain alcohols to be used as biofuels
Ben Schilling Skills
Ben Schilling Education Details
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UclaChemical Engineering
Frequently Asked Questions about Ben Schilling
What company does Ben Schilling work for?
Ben Schilling works for Caribou Biosciences
What is Ben Schilling's role at the current company?
Ben Schilling's current role is Process Development Engineer at Caribou Biosciences.
What is Ben Schilling's email address?
Ben Schilling's email address is be****@****inc.com
What is Ben Schilling's direct phone number?
Ben Schilling's direct phone number is +191686*****
What schools did Ben Schilling attend?
Ben Schilling attended Ucla.
What skills is Ben Schilling known for?
Ben Schilling has skills like Chemical Engineering, Validation, Hplc, Fermentation, Biotechnology, Biochemistry, Design Of Experiments, Technology Transfer, Biofuels, Cell Culture, Process Engineering, Analytical Chemistry.
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