Pascal Benderitter Email & Phone Number

Vienna, AT

Hit generationHit-to-lead & Lead-to-candidateMolecular modelingOutsourcing

Dijon, Bourgogne-Franche-Comté, FR

ODS-101 / OPM-101 FIH leadPhase 1 - enabling project leader (regulatory, clinical preparation)Preclinical operations project leader (CMC, toxicology, regulatory)Hit-to-Lead up to Late lead optimization project leaderMachine learning integration in discovery programs

Dijon Cedex, FR

Hit-to-Lead up to Late lead optimization project leaderPreclinical operations manager

Dijon Cedex, FR

. Lead medicinal chemistry efforts of internal research programs from hit generation to preclinical candidate identification (RIPK2...). Lead research programs in collaboration with pharmaceutical partners. Elaborate and maintain a KOL and clinical network to support prioritization of early phase programs. Management of CROs (identification, evaluation and.

Lausanne, Vaud, CH

. Development of novel scaffolds and enabling scale-up synthesis. Design and synthesis of focused libraries of active molecules. Multidimensional optimization of lead compounds (activity, selectivity, ADME-Tox, PK/PD...). Active participation to 5 medicinal chemistry programs: 1. Allosteric modulators of AMPA receptor (hit-to-lead program) 2. Abeta.

Synthesis of novel kinase scaffolds and hit generation for oncology targetsActive participation in the development of novel FGFR inhibitors (Lead optimization and Late Lead Optimization program)Results:. Development of unique and patentable kinase scaffolds. Design and synthesis of >250 compounds. Active participation in the filing of a patent

FR

Industrial grant via CIFRE contract (ANRT)Design and synthesis of CNS agents- Development of GPCR (G Protein Coupled Receptor) agonists/antagonists- Development of new methodologies and drug optimisation- Drafting of research reports / scientific presentations in French and in English

PhD diploma performed in the lab of Dr. Bourguignon, part of the "Laboratoire d'Innovation Thérapeutique" (Director: Prof.Hibert)The PhD work was performed through a CIFRE grant and under the supervision of Neuro3D (CNS-focused startup).

6 months contract at Morphochem AG (Dr. Hubschwerlen)Synthesis of building blocks for combinatorial chemistry- Optimisation of synthetic pathways- Development of an automated biological test mimicking the membrane permeability

Basel, Baselstadt, CH

6 months contract, Leonardo funding (Dr. Nussbaumer, lab. Dr. Horvath)Development of skin anti-inflammatories- Synthesis of chiral aryl sulfonamides as steroid sulfatase inhibitors

Phd, Organic Chemistry

Master, Pharmacology - Pharmacochemistry

Master, Organic And Macromolecular Chemistry

Master, Organic Chemistry