Ben Kaplan Email & Phone Number

Cambridge, Massachusetts, Us

LCT is a technological creator and end-to-end solution provider of rapid 3D shielded-tissue clearing and imaging, including specialized tissue processing, light-sheet microscopy, and software-analytics + data storage products, as well as exploratory CRO services.‣ Designed and deployed backend image loading and interface features for SmartAnalytics® all-inclusive 3D processing, registration, and analysis product within a SPRINT-frameworked team of software engineers.‣ Drove development of accelerated computing for algorithmic steps in live image processing on full-stack SPIM acquisition. Extended image processing into PyTorch framework for GPU and Machine Learning applications.‣ Supervised nine-step sample-processing and analysis automated workflow running distributed docker packaging on in-house cluster.

Boston, Massachusetts, Us

Foundation is the market leader in precision medicine diagnostics. Provides cancer patients and physicians with the comprehensive genomic molecular insights needed to prescribe the top targeted/IO therapies and empowers biopharma partners to develop the treatments of tomorrow.‣ Led data/visualization programming and reporting on 130 analyses for chief biopharma partner using custom-built python and R code.‣ Spearheaded bioinformatic research on 13 active manuscripts with collaborators across academia and industry as principal analyst.‣ Implemented validation and oversaw all documentation of FoundationCore®: a 750k patient dataset of 300 specimen/variant features.‣ Enhanced FoundationCore® content generation and investigative toolset codebases; contributed to 19 quarterly code development cycles by adding features such as FDA CDx claim annotation, rapid XML extraction, expanded script querying, and automatic QC-ing.

Boston, Massachusetts, Us

Tarrytown, New York, Us

Regeneron is a pioneering biotech renowned for cultivating life-transforming therapeutic antibody medications from invention to commercialization via a rigorous, ultraprecise molecular genetics discovery pipeline and trailblazing investment in sequencing over a million human exomes.‣ Devised programmatic pipeline interpreting sequencing data for a novel assay since used to validate the safety of early-candidate cancer-targeting bispecific antibodies for human usage.‣ Built a bioinformatic software suite improving designs of CRISPR, TaqMan, and other oligo-mediated assays used across Regeneron by enabling scientists to harmonize for Regeneron-specific strain variations in mice.‣ Produced backend processes powering interactive applications for user-defined analyses of BED, VCF, and other NGS-derived data, optimized for a distributed Linux HPC environment.

New York, Ny, Us

‣ Programmed prototype web platform for differential gene expression visualization, interpretation and downstream enrichment examination facilitating future drug development.‣ Discovered enrichment conveying a novel central role for NUCKS1 transcription factor in Alcoholic Liver Disease.

Main focus was on expanding the Hospital’s social media programs and reaching out to potential corporate partners.

Valhalla, New York, Us

Focused mainly on the technical design of the hospital's case management review systems and human data analysis.

Champaign, Il, Us

My research combined two forms of self-healing concrete: bacterial concrete and Engineered Cementitious Composite (ECC). Bacterial concrete employs bacteria to re-glue cracks using biocalcification, while ECC ties the concrete together with tailored fibers enabling the cracks to stay so small that they can heal spontaneously. I combined these two forms of concrete and tested the "hybrid" in multiple settings, including lab, underground and field environments. I also ran tests to assess the compatibility between the bacteria and fibers. The results show that the combined approach self-healed more effectively and that self-healing was statistically as effective in the underground environment as in the optimal control environment.