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Benjamin Brakel is listed as Medical Student in Glioblastoma Stem Cell Research Program at Centre for Discovery in Cancer Research (CDCR) - McMaster University, based in Vancouver, British Columbia, Canada. AeroLeads shows a matched LinkedIn profile for Benjamin Brakel.
Benjamin Brakel previously worked as Glioblastoma Stem Cell Research, Dr. Sheila Singh Laboratory at Centre For Discovery In Cancer Research (Cdcr) - Mcmaster University and Neurosurgery Research (Clinical) - Dr. Faizal Haji at Bc Children'S Hospital Research Institute. Benjamin Brakel holds Doctor Of Medicine - Md, Medicine from The University Of British Columbia.
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Working at the intersect of functional genomics and immunotherapeutics to uncover and target novel vulnerabilities of brain cancer stem cells, while driving clinical advances in neurosurgical techniques.
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Hamilton, Ontario, Canada
Co-Second Author, Nature Medicine: Through integrative genomic analyses and genome-wide genetic perturbation screens, we identified a PTP4A2-ROBO1 axonal guidance signaling axis as a modulator of glioblastoma stem cell migration and tumorgenicity. Targeting this dependency using ROBO1 CAR T cells doubled median survival in patient-derived xenograft models.
Vancouver, British Columbia, Canada
First Author, In Progress: Through conducting a large longitudinal cohort study, we have shown that the addition of barrel stave osteotomy to endoscopic suturectomy for craniosynostosis improves long-term cephalometric outcomes while having no significant effect on operative burden.
Vancouver, British Columbia, Canada
First Author, In Progress: Conducting large-scale international survey on practice patterns and perspectives on endovascular therapy for the treatment of cerebral venous thrombosis. With 861 respondents across 61 countries, we have developed a comprehensive characterization of indications, techniques, and long-term management for endovascular treatment of.
Vancouver, British Columbia, Canada
First Author, Journal of Neurological Surgery Part B, Skull Base: Proof of concept of a novel technique using jugular bulb pressure to optimize head positioning prior to vestibular schwannoma resection, demonstrating reduced intracranial pressure during surgery.First Author, In Progress: Conducting longitudinal survey of return to work function in patients.
Toronto, Ontario, Canada
First Author, Research and Practice in Thrombosis and Haemostasis: Identified MRI T2 mapping as a promising tool for detecting early biochemical cartilage damage in pediatric hemophilic arthropathy, before it's visible with standard radiographic methods. Validated as an early diagnostic tool before irreversible damage occurs.
Hamilton, Ontario, Canada
Biocomputational design of small molecule therapeutics for SARS-CoV-2 preceding the synthesis and biochemical evaluation of these compounds in experimental assays. Developed compounds with high binding affinity, synthetic tractability, and drug-like properties.
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Benjamin Brakel works for Centre for Discovery in Cancer Research (CDCR) - McMaster University.
Benjamin Brakel is listed as Medical Student in Glioblastoma Stem Cell Research Program at Centre for Discovery in Cancer Research (CDCR) - McMaster University.
Benjamin Brakel is based in Vancouver, British Columbia, Canada while working with Centre for Discovery in Cancer Research (CDCR) - McMaster University.
Benjamin Brakel has worked for Centre For Discovery In Cancer Research (Cdcr) - Mcmaster University, Bc Children'S Hospital Research Institute, Vancouver General Hospital, The Hospital For Sick Children, and Michael G. Degroote Institute For Infectious Disease Research.
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Benjamin Brakel holds Doctor Of Medicine - Md, Medicine from The University Of British Columbia.
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