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Study and development of Artificial Metalloenzymes

3rd Thesis year at the “Institut Lavoisier de Versailles“Studied the uncommon reactivity of naphthaleneWorked on the functionalisation of naphthalene and its precursors using mainly C-H Activation methodology. Developed various reaction conditions dedicated to naphthalene derivatives (methoxylation, arylation, annulation...) leading to different polycyclic patternsIsolated and characterized multiple undescribed organic chemicalsExplained the selectivity of reactions I have developed using computational chemistry. Performed DFT mechanistic study the mechanism of C–H functionalisation using a transient directing groupAttended various conference dealing with state-of-the-art organic synthesis methodologies. Presented my work during both poster sessions and oral communications. Published my results into high-impact peer-reviewed journalsTaught organic synthesis to L1, L2 & L3 students during practical classes (128h/yr)

Optimisation of alkyl anthraquinone synthesis, a catalyst in Hydrogen Peroxide productionWorked in a kilo lab in coordination with factories to find a more efficient and a greener way to synthesize this catalyst.Improved the current conditions, and tested new ways to obtain this product

Worked on my own research project, in collaboration with UT Southwestern - Synthesized and purified specific oligopeptides, which may have the ability to stop the metastasis of prostate cancer cells - Learned how to work with bigger molecules - Became more independent in the lab - Enhanced my English skills

- Worked on a research project to develop new creative ways to synthesize unnatural amino acids from achiral precursors- Became familiar with varied lab work techniques & reactions - Improved my analytical chemistry skills as much as my lab work speed and efficiency