Senior Staff Scientist
CurrentDevelopment of native, intact, and top/down technologies
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Benjamin N. Nigjeh is listed as Proteomics | Mass Spectrometry | Data Science at Northwestern Proteomics Center of Excellence, based in Glencoe, Illinois, United States. AeroLeads shows a matched LinkedIn profile for Benjamin N. Nigjeh.
Benjamin N. Nigjeh previously worked as Senior Staff Scientist at Northwestern Proteomics Center Of Excellence and Senior Research Scientist II at Exelixis. Benjamin N. Nigjeh holds Postdoc, Clinical Proteomics from University Of Washington.
I am an analytical biochemist with a passion for unraveling the complexities of biological systems through mass spectrometry proteomics and data science. With 15 years of experience in the field, I have honed my skills in experimental design, data acquisition, and advanced data analysis techniques. My expertise lies in leveraging mass spectrometry to analyze complex protein samples, identify biomarkers, and elucidate molecular mechanisms. I am also proficient in programming with Python and R, enabling me to develop custom analytical pipelines and algorithms for data interpretation.I am seeking opportunities to apply my analytical and computational skills in a dynamic research environment and industry setting. Let's connect to explore potential collaborations or career opportunities!
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Development of native, intact, and top/down technologies
Alameda, California, US
-Conducted structural analysis of key oncogenic proteins to support X-ray crystallography and cryo-electron microscopy (Cryo-EM).-Collaborated with cross-functional teams to design and execute experiments aimed at elucidating the structural basis of protein function and its role in cancer development.-Applied advanced computational modeling techniques to.
Boston, MA, US
-Led GLP-compliant pharmacokinetic (PK) studies to profile drug candidates in animal models, focusing on tissue and blood distribution.-Designed and executed study protocols, ensuring compliance with regulatory guidelines and quality standards.-Developed and validated analytical methods for quantifying drug concentrations in various matrices using LC-MS/MS.
La Jolla, CA, US
-Led activity-based ATP probe profiling of endogenous key kinases before and after non-covalent engagement with small molecules for drug potency and specificity screening.-Developed and optimized assays to assess kinase activity and small molecule engagement using activity-based probes and mass spectrometry.-Collaborated cross-functionally to design and.
Los Angeles, CA, US
-Managed a state-of-the-art proteomics core facility, providing high-quality proteomics services and support to over 40 research groups across multiple institutes.-Collaborated with researchers to design and implement proteomics experiments, including sample preparation, mass spectrometry analysis, and data interpretation.-Established and maintained.
Seattle, WA, US
-Led the development of an extensive clinical blood assay capable of quantifying over 3500 blood proteins from less than 10 microliters of human plasma, enabling high-throughput biomarker discovery and validation studies.-Conducted global identification of circulating glycoproteins, employing mass spectrometry-based proteomics and glycoproteomics.
Buffalo, NY, US
-Developed a highly sensitive and accurate targeted quantification technique for the pre-clinical assessment of pharmacokinetic parameters for therapeutic proteins from tissue and blood of animal models, enabling precise measurement of drug levels and evaluation of drug efficacy.-Conducted global discovery proteomics pharmacodynamic studies after a.
Groningen, NL
-Led LC/MS identification of oxidative drug metabolites, employing state-of-the-art mass spectrometry techniques to elucidate metabolic pathways and identify potential toxic or pharmacologically active metabolites.-Developed SRM-based quantification methods for drug metabolites, enabling precise measurement of metabolite concentrations in biological.
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Benjamin N. Nigjeh works for Northwestern Proteomics Center of Excellence.
Benjamin N. Nigjeh is listed as Proteomics | Mass Spectrometry | Data Science at Northwestern Proteomics Center of Excellence.
Benjamin N. Nigjeh is based in Glencoe, Illinois, United States while working with Northwestern Proteomics Center of Excellence.
Benjamin N. Nigjeh has worked for Northwestern Proteomics Center Of Excellence, Exelixis, Vertex Pharmaceuticals, Activx Biosciences, and Keck Medicine Of Usc.
You can use AeroLeads to view verified contact signals for Benjamin N. Nigjeh at Northwestern Proteomics Center of Excellence, including work email, phone, and LinkedIn data when available.
Benjamin N. Nigjeh holds Postdoc, Clinical Proteomics from University Of Washington.
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