Benjamin Smyth Email & Phone Number

Pleasanton, California, US

Pleasanton, California, US

Pleasanton, California, US

• Provided technical advice, mentoring, and assisted in experimental troubleshooting for both Field Application Scientists and 10x Genomics customers.
• Developed the technical knowledgebase, led technical training to global support organization, and delivered the customer perspective throughout the product development process as support representative for Chromium.
• Provided technical troubleshooting expertise for Chromium Controller escalations as Technical Support subject matter expert.
• Developed new inquiry/complaint reporting codes in Zendesk, resulting in improved cross-application reporting for 10x quality team and core teams. Generated template in Zendesk Explore for consistencies in reporting.
• Facilitated the development of an automated Salesforce replacement form with Productivity Engineering team, resulting in an improved support replacement process.

Pleasanton, California, US

Aliso Viejo, CA, US

R&D Project lead for a research collaboration involving liquid biopsy of cancer patients undergoing immunotherapy treatment.o cfDNA extraction and NGS protocol optimization led to a 3-fold increase in depth of coverage and increased assay sensitivity.

Aliso Viejo, CA, US

• Designed and developed a targeted Cardiology NGS gene panel used for precision medical diagnoses.
• Developed a high-throughput primer design process to generate Sanger confirmation assays.o Streamlined process that lowered development time by approximately three months and saved hundreds of hours in full-time labor.

Aliso Viejo, CA, US

• Successfully developed and validated NGS assays incorporated into a CAP accredited and CLIA approved clinical laboratory.
• Aided the clinical laboratory next generation and Sanger sequencing teams to troubleshoot through complications and streamline workflow.
• Experienced in somatic NGS assays, MLPA, mass array, and Long Range PCR for pseudogene resolution.

Aliso Viejo, CA, US

• Successfully designed, developed, and validated standard operating procedure (SOP) for Sanger gene sequence confirmations.
• Effectively coordinated with an eight person research team to sequence over 10,000 exome samples to better understand links between patients diagnosed with ovarian and breast cancer.
• Aided in the design and development of research and exploratory assays for assessment of gene function.

Fullerton, CA, US

• Successfully developed the plant-two hybrid system for detecting protein/protein interactions in the cytoplasm of living plant cells.
• Optimized recombinant DNA cloning techniques to create numerous sets of interacting partners to test in the plant-two hybrid system using A. tumefaciens bacterial expression in plants.
• Engineered transgenic N. benthamiana plant line containing the Tm22 gene.
• Analyzed data and troubleshot around complications throughout experiment while using techniques such as PCR, agarose gel electrophoresis and SDS-PAGE, agroinfiltration, plant protein extraction, and western blotting.
• Mentored and trained undergraduate students to assist the progression of their research.

Fullerton, CA, US

• Facilitated the learning of core cell biology concepts.
• Applied concepts learned in lecture to the laboratory to assist student understanding.
• Demonstrated and facilitated learning of techniques such as column chromatography, cellular fractionation, enzyme assays, spectrophotometry, and bright field microscopy.

Master'S Degree, Molecular Biology

Bachelor'S Degree, Molecular Biology