Brian Ferrer-Hernández, Mba Itm, Eit Email & Phone Number

Carolina, Puerto Rico

Puerto Rico

• Lead the team responsible for STEM, Academia, and K12 collaborations at Lilly del Caribe. Oversee team’s agenda, manage budget, and foster collaborations with organizations supporting the community and academia.

Puerto Rico

• Supported COOP Program talent acquisition and oversight, enhanced the program with professional development and teambuilding activities, and created standardized guides for coaches and participants.

Puerto Rico

• Serve as a vital link between participants and program administration, ensuring the program's success and sustainability. Successfully impacted 11 cohorts, each averaging 25 participants.

Puerto Rico

• Supported the creation of a Value Stream Map and an operational model for all manufacturing peripheral activities associated with two molecules.• Coordinated five Product Changeovers, two shutdowns, and special activities for the Fermentation Building.• Ensured continuity and leadership for Fermentation and Isolation teams by covering for Associate Directors of Manufacturing Operations.• Supported audit readiness, regulatory inspections (FDA, GQAC, Anvisa, PMDA), and site self-inspections. Created and presented storyboards during regulatory inspections.• Served as lead investigator for minor, moderate, and major deviations at the site and within the Fermentation Building, ensuring thorough analysis and resolution.• Led the coordination of the Microbial Recovery Testing project, fostering cross-functional integration of key areas and stakeholders.

Puerto Rico

• Aligned, oversaw, and escalated conflicts in site initiatives impacting the Manufacturing Execution Systems (MES).

Puerto Rico

• Managed equipment for Crystallization, Filtration, and Drying areas, ensuring assets remained qualified and validated, while conducting routine process monitoring and providing technical support to resolve complex issues using Root Cause Analysis (RCA) techniques.• Led investigations for minor, moderate, and major deviations in the process step, ensuring thorough analysis and resolution. Awarded in the “Reliable Supply of Medicines” category at the 2021 Lilly Excellence Awards for supporting the resolution of a complex deviation in the Purification Building.• Implemented a denatured alcohol buffer usage reduction initiative, achieving significant cost avoidance, operational hours savings, and reducing over 230,000 liters of regulated waste annually. This initiative won the “Sustainable Use of Environmental Resources” category at the 2022 Lilly Excellence Awards.• Executed the Air Sweeps engineering initiative to reduce drying time, involving strategy design, change control creation, protocol development, and engineering runs execution support.• Enhanced phenol dispensing operations improving safety and led projects to increase reliability of integrity tester and control valves.• Served as Process Team expert and liaison for environmental programs (LDAR, PSM, Title V Air permits), supporting personnel qualification and area compliance. Acted as Site Element Owner for PSM Pre-Startup Safety Review (PSSR) element.• Supported revalidation of Crystallization area Process Hazard Review and Purification Building Combustible Dust assessment.• Enabled a seamless area transition by mentoring and guiding the incoming process engineer.

Puerto Rico

• Managed equipment for the Reversed Phase chromatography area, ensuring assets remained qualified and validated, while conducting routine process monitoring and providing technical support to resolve complex issues using Root Cause Analysis (RCA) techniques.• Led investigations for minor, moderate, and major deviations in the process step, ensuring thorough analysis and resolution.• Optimized Slow Flow and Capoff phases, reducing over 80,000 liters of Acetonitrile and 820,000 liters of Sodium Acetate annually, leading to cost, time, emissions, and waste reductions.• Led projects to improve temperature control valve leaks and incorrect installations of sampling valves’ Spring Close Valve Seal System.• Supported the design and implementation of the process step electronic ticket, becoming a recipient of the “Team Lilly Accelerate” award at the 2021 Lilly Excellence Awards.• Acted as the Process Team expert and liaison for environmental programs (LDAR, PSM, Title V Air permits), enhancing personnel qualification and area compliance. Received the global 2020 HSE Environmental Impact Award for contributions to LDAR compliance.• Supported the execution of engineering runs to optimize crystallization area washes.• Facilitated engineering runs for testing a new resin for column packing operations and supported its permanent implementation.• Enabled a seamless area transition by mentoring and guiding the incoming process engineer.

Wickliffe, Ohio

Planned, budgeted, oversaw and documented several projects to ensure these were within scope and headed towards completion. *Analyzed and interpreted Tapered Tube data, to emit a technical report with recommendations on liquid dropout limits standards on Gasoline and Diesel additive formulations to minimize excursions and complaints.*Initiated, budgeted, launched and oversaw an initiative to update wear scar and lubricity data for lubricity improvement additives. Work will provide ground for the development of ongoing initiatives and to update marketing data.*Initiated, budgeted, launched and oversaw an initiative to recycle a solvent waste stream and use it as a solvent replacement in some formulations. Preliminary results suggest solvent is safe to use and will not affect the performance of additives. Project will lead to savings in waste disposal plus the costs of the solvents used.*Secured budget and gave continuity to an initiative that looks to understand how sulfur is incorporated into an additive formulation with the goal of increasing its content to better compete in the market.

Las Piedras, Puerto Rico

Developed an UPLC method for the simultaneous analysis of two APIs in a pharmaceutical formulation using Ion-pair chromatography.*Found appropriate conditions for the Content Assay and Content Uniformity tests.*Simultaneous analysis conditions are estimated to save three analyst weeks and over 400 L of waste per year.*Work competed in Merck’s Science and Technology day and earned 2nd place in poster competition.

Pr05 Carolina, Puerto Rico

Created a tool to measure the cycle time and detect its variation for insulin production processes and all of its stages.* Tool acquires data from OSI PI-Batch View and OSI PI-Datalink, processes it through the use of VBA and pivot tables, and generate dynamic graphs to clearly represent the data.* Tool permits the optimization of the processes' cycle time and the early detection of any outliers.Migrated, optimized, and reworked existing tools aimed at monitoring the Clean in Place systems of the manufacturing buildings.* Based in OSI-Soft PI, and powered by a new and efficient VBA code, tools allow the monitoring of held time, circuits and cycle time of the clean in place systems in order to permit the processes' optimization and the early detection of issues before impacting production.Evaluated, Proposed, Created, Documented and Implemented seven equivalent changes for Process Filters.* Besides specifications evaluation, differential pressure testing was performed to prove equivalency.* Savings potential estimated as an average of up to 60% annually. Supported Title V Permits Emissions Monitoring and Calculations tasks.* Created special instructions to aid with the monitoring of emissions.* Created several isometric drawings to aid with the creation of emission models in Aspen.* Processed models data in order to highlight and convert essential data.Evaluated the different point of uses of the Purified Water with Endotoxins Control system in order to detect design gaps that could contribute to specification excursions and propose solutions to address those gaps.* Pipe's flow orifices were evaluated and their type, diameter and positions were documented.* Testing was performed to identify minimal flow orifices diameter requirements to avoid drainability issues.* Detected design flaws were reported and a change to address those gaps was pending to be implemented.

Painesville, Ohio

Helped Lubrizol’s Painesville facility to comply with environmental requirements established by local, state and federal agencies, such as the Environmental Protection Agency (EPA).• Aided Lubrizol Painesville facility to reach full compliance with the Leak Detection and Repair (LDAR) EPA requirements. • Traced back all components from the point of waste generation back to four, out of six, Recovered Organics (RO) tanks via line walks.• Worked with an external contractor performing line-walks and obtaining isometric sketches of new or outdated components for the LDAR program; work involved tracing in five buildings and eight loading stations.• Proposed and scheduled tests for a relief device monitoring system, based on acoustic sensing technology for LDAR systems.• Created technical work instructions for excavations and Reportable Quantities (RQ) flowsheets made available for the facilities.• Generated reports for regulatory agencies on sewer and air emissions.

Wickliffe, Ohio

• Developed and implemented a corrosion study for a best in class friction modifier and determined the best material of construction for a multimillionaire expansion project for its production. • Material performed better and is expected to cost 25% less in comparison to the material previously quoted.• Designed and ran several solubility studies to determine the appropriate solvents and mixing rates for cleaning the reactors of the friction modifier product.• Developed experimental setups as a way of gathering data on how different methods of incorporating antifoam would affect their performance. • Modeled variations of Lubrizol’s tanks and generated reports on key parameters that affect antifoam performance, using VisiMix modeling software.• Red-lined reviewed one of Lubrizol's reactor systems and worked with the Computer Aided Design and Drafting (CADD) team to update several Process and Instrumentation Diagrams (P&IDs) for that system.

University Of Puerto Rico At Mayaguez

*Development of a multifunctional material, based on Bismuth Ferrite, to be used in the construction of novel storage and optical devices, and its characterization using various methods.*Synthetized Bismuth Ferrite (BFO) powders and doped them with various compounds, such as Silver and Calcium.*Successfully created thin films of BFO, permitting a better method of analysis for the sample.*Analyzed and normalized complex XRD and VSM data using specialized software such as Match, PowderX and Origin.*Data proved that magnetic and electrical properties of the material were improved per the dopant level and that heat treatment’s time, temperature, and atmosphere greatly affect the formation of parasite phases in the material. *Determined the optimal level of dopants for the appropriate co-doping of the system and the creation of the multi-functional material.

University Of Puerto Rico At Mayaguez

Chemotherapeutic approach to the treatment of tumours and the chemistry involved in the synthesis of those ligands, to be used in the construction of novel chemotherapeutic drug, and their analysis through techniques like NMR, TLC and Chromatography. *Synthetized several amino acid derived compounds, including derivatives of L-phenyl aniline, and functionalized those using protection and deprotection mechanisms.*Confirmed structures of intermediate steps of the mechanisms using NRM data.*Worked with the determination of solvents capable of separating the product of impurities, based on polarities and TLC analysis.

University Of Puerto Rico At Aguadilla

Effect on wind direction on sand accumulation on the Coast of Puerto Rico at Isabela.As part of a team of researchers, I contributed to the design and development of a mechanism with the goal of measuring the wind direction’s effect on sand accumulation and its effect on the creation of sand dunes, at the coast of Isabela’s, Puerto Rico, beach.

Master Of Business Administration - Mba, It Management

Accredited by NWCCU and ACBSP

Bachelor Of Science - Bs, Chemistry, High Honor

Accredited by MSCHE and ACS

Bachelor Of Science - Bs, Chemical Engineering, High Honor

Activities and Societies: 2014 President at the American Institute of Chemical Engineers (AIChE) Student Chapter of the University.