Bill Gamble Email & Phone Number

Des Moines, Iowa, United States

Ankeny, Ia

Responsible for obtaining ISO 17025 accreditation, developing and maintaining the Quality Management System.

Eldora, Ia

Responsible for all chemical aspects of current product line, including performing QC testing, doing Research and Development for new products and product improvements, maintaining certifications, and writing and auditing adherence to quality documentation.

Ames, Ia

Responsibilities: Managing Analytical Services Department-Supervising a team of 5 Chemists and 1 Microbiologist-Responding to customer complaints and concerns. -Developing analytical methods and experiments to determine causes of product defects. -Devising solutions to remedy and prevent defective products. Support and repair of analytical instrumentation (gas chromatograph, spectrometers and flow injection analyzers).Supervising Incoming Quality Control… Show more Responsibilities: Managing Analytical Services Department-Supervising a team of 5 Chemists and 1 Microbiologist-Responding to customer complaints and concerns. -Developing analytical methods and experiments to determine causes of product defects. -Devising solutions to remedy and prevent defective products. Support and repair of analytical instrumentation (gas chromatograph, spectrometers and flow injection analyzers).Supervising Incoming Quality Control team.-Team of 2 quality control technicians responsible for testing of raw materials used for production.Managing Out-Going Inspection Department- Managing a team of 4-6 quality inspectors.- Reporting inspection results to customers and explaining counter-measures.Successes:Determined cause of poor cadmium column efficiency in flow injection analyzer. Identified cause of high blanks in Cyanide analysis using micro-distillation method. Led Kaizen to reduce variation in powder pillow production.Improved chromatographic method and developed specifications for DPD product line.Determined cause of high results in Ammonia-free micro-distillation and developed approach to treat membranes to use cheaper source raw material. Show less

Des Moines, Ia

Responsibilities: Developing and validating analytical methods for active compounds in pet foods and pet food ingredients (HPLC and GC). Determining and providing documentation regarding composition and efficacy of ingredients in support of requests for approval by the FDA and EU. Developing purification processes and transferring these to production scale. Providing analytical support to sales groups and customers as needed. Identification of potential new products and… Show more Responsibilities: Developing and validating analytical methods for active compounds in pet foods and pet food ingredients (HPLC and GC). Determining and providing documentation regarding composition and efficacy of ingredients in support of requests for approval by the FDA and EU. Developing purification processes and transferring these to production scale. Providing analytical support to sales groups and customers as needed. Identification of potential new products and research to determine availability, identity of compounds of interest, and current assay methods. Supervising a team of up to five, including chemists, a microbiologist, and an engineer. Successes: Launched an antioxidant rosemary extract for the stabilization of petfood diets, including optimizing production scale purification process, developing and validating HPLC and GC analytical methods for the active component of the extract, and gathering data to demonstrate the efficacy of the product. Developed a method for the purification of mannoheptulose. Optimized a method for the extraction of mannoheptulose from avocado. Developed and validated HPLC method for analysis of the mannoheptulose. Successfully launched a probiotic product for equine supplement market, including gathering safety and efficacy data through trials in collaboration with Iowa State University. Developed and wrote patent application for method of application to deliver probiotic to extruded petfoods. Show less

Longmont, Co

Responsibilities: Directing the activities of three to five people in conducting research to bring new herbals to market. Isolating and identifying active or marker compounds. Developing purification processes and transferring these to production scale. Developing and validating assay methods (primarily HPLC and colorimetric) Contacting and arranging for CRO's to perform animal and human clinical trials on various herbal formulations. Identifying potential new products… Show more Responsibilities: Directing the activities of three to five people in conducting research to bring new herbals to market. Isolating and identifying active or marker compounds. Developing purification processes and transferring these to production scale. Developing and validating assay methods (primarily HPLC and colorimetric) Contacting and arranging for CRO's to perform animal and human clinical trials on various herbal formulations. Identifying potential new products and determining availability, identity of compounds of interest, and current assay methods. Successes: Developed and patented a method for the removal of quintozene pesticide from ginseng. This allowed BIE to be the only company allowed to bring pesticide contaminated ginseng into the US. Developed and patented a process for the purification of policosanol from beeswax. Oversaw scale up of this product from bench to production scale, including developing analytical methods, designing large scale equipment, performing QC on the product, and supervising the production personelle during production start-up. Show less

Frederick, Md

Responsibilities: Isolating and determining structure of anticancer agents with therapeutic potential. Using 500 MHz Varian NMR spectrometer for a variety of modern NMR techniques such as HMBC, HMQC, COSY, and NOESY for structure elucidation. Separating complex mixtures through bioassay-guided fractionation using a number of chomatoagraphic techniques including normal and reversed-phase HPLC (Rainin and Waters systems); size-exclusion, ion-exchange, normal, and reversed phase liquid… Show more Responsibilities: Isolating and determining structure of anticancer agents with therapeutic potential. Using 500 MHz Varian NMR spectrometer for a variety of modern NMR techniques such as HMBC, HMQC, COSY, and NOESY for structure elucidation. Separating complex mixtures through bioassay-guided fractionation using a number of chomatoagraphic techniques including normal and reversed-phase HPLC (Rainin and Waters systems); size-exclusion, ion-exchange, normal, and reversed phase liquid chromatography. Successes: Development and implementation of a dereplication process to prevent time lost in purifying and performing structural elucidation of previously reported compounds. Used this technique to identify over 20 previously identified marine components with cytotoxic activity. Isolation and structural elucidation of novel compounds with activity in 60 tumor cell-line assay. Show less

Iowa City, Ia

Isolating and determining structure of more than 20 bioactive natural products Growing fungal cultures, performing bioassays, and fractionating extracts using a wide variety of chromatographic techniques including HPLC (Waters and Beckman systems), counter-current chromatography, and radial chromatography. Using Bruker 300, 360, and 600 MHz NMR spectrometers including familiarity with a variety of NMR processing software including Felix, NUTS, PCNMR, and UXNMR Using TRIO 1 mass… Show more Isolating and determining structure of more than 20 bioactive natural products Growing fungal cultures, performing bioassays, and fractionating extracts using a wide variety of chromatographic techniques including HPLC (Waters and Beckman systems), counter-current chromatography, and radial chromatography. Using Bruker 300, 360, and 600 MHz NMR spectrometers including familiarity with a variety of NMR processing software including Felix, NUTS, PCNMR, and UXNMR Using TRIO 1 mass spectrometer Teaching Assistant for Organic Chemistry laboratory and General Chemistry discussion sections Directed Study in Inorganic Chemistry Northwestern College Reactivity studies involving replacement of isonitrile groups of chromium hexacarbonyl with other isoelectronic species Show less

Ph.D, Organic Chemistry

Thesis title: Antifungal Natural Products from Coprophilous and Mycoparasitic Fungi

Doctor Of Philosophy (Phd), Organic Chemistry

Experience: Isolating and determining structure of more than 20 bioactive natural products Growing fungal cultures, performing bioassays.

Ba, Chemistry

Activities and Societies: Honors/Awards- National Merit Finalist, Maytag Co. Full Scholarship, Northwestern College Presidential.

Ba, Chemistry