Bill Howarth Email & Phone Number

Novato, CA

Technical TrainingDeveloped a structured learning program centered on manufacturing processes for 250 floor staff (and QA, QC, and Validation groups): New hire fundamentals of bio-processing; cell culture and purification process previews for product campaign change; advanced topics in process science and technology. 92% of students “highly recommend”.

Novato CA

Technical Transfer and Manufacturing SupportAccurate translation of continuous cell culture process from pilot to commercial manufacturing for successful process qualification campaign. Managed technical operations meetings.Acted as person-in-the-plant and upstream subject matter expert.Responsible for troubleshooting, product impact assessment, and.

Emeryville, CA

Manufacturing SupportActed as technical campaign lead and process science trainer for yearly manufacturing of a critical diagnostic reagent at CMO.Responsible for investigations in a microbial manufacturing facility (2 X 10,000 L scale), and a small fermentation facility with 26 different products (10, 30 and 250L scale).Reconfigured two large scale UF/DF.

Emeryville, CA

Process SupportResponsible for fast track high quality troubleshooting and deviation investigation and resolution at Vacaville Manufacturing Facility.Increased the yield of a refold process by 25%. Responsible for studies to support manufacturing reproducibility.Recognized as key resource for scale-up and successful implementation of processes at the.

Emeryville, CA

Conducted quality management training for Biotechnology technicians, scientists and managers.

Emeryville, CA

Process Development and Process TransferDesigned processes, control strategies, and procedures for batch, fed-batch and continuous fermentations of yeast, bacteria and mammalian cells.Developed analytical and scale up models to increase pilot lab capabilities: kLa; O.U.R.; heat generation; metabolite utilization; and cell growth.Optimized fermentation and.

South San Francisco, CA

Conducted experimental recombinant yeast and bacterial fermentations to evaluate expression systems and study scale-up issues.

Berkeley, VA

Responsible for all aspects of sterile, low pyrogen cell culture media production. Designed and implemented new production system that increased liquid medium lot sizes 500% and reduced process time by 50%.

Berkeley, CA

Implemented complex field sampling and data collection procedures for Western Spruce Budworm life-table and parasite research.

Concord, CA

Independently designed and implemented studies to assess impacts of proposed hydroelectric projects on forest resources in California. Coordinated with utilities and wildlife agencies.