Billy Wu

Billy Wu Email and Phone Number

Chief Scientific Officer @ BioAnalytix, Inc.
Boston, MA, US
Billy Wu's Location
Greater Boston, United States, United States
Billy Wu's Contact Details

Billy Wu personal email

n/a
About Billy Wu

Billy Wu is a Chief Scientific Officer at BioAnalytix, Inc.. He possess expertise in protein chemistry, lc ms.

Billy Wu's Current Company Details
BioAnalytix, Inc.

Bioanalytix, Inc.

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Chief Scientific Officer
Boston, MA, US
Website:
bioanalytixinc.com
Employees:
5
Billy Wu Work Experience Details
  • Bioanalytix, Inc.
    Chief Scientific Officer
    Bioanalytix, Inc.
    Boston, Ma, Us
    View
  • Crystal Bio, A Member Of Crystal Pharmatech
    Chief Scientific Officer
    Crystal Bio, A Member Of Crystal Pharmatech Jan 2024 - Present
    Analytical and bioanalytical analyses in CMC, preclinical and clinical samples for biological products
  • Bioanalytix, Inc.
    Chief Scientific Officer
    Bioanalytix, Inc. Jan 2013 - Oct 2022
    o Determination of critical quality attributes in therapeutic proteins by advanced LC-MS based characterization including precise N/O-linked glycostructure and linkage assignment, sequence variation and modification, disulfide mapping with free cysteine and scrambling analysis.o Ex-vivo analysis of PTMs for therapeutic proteins in PK blood or tissue and for DNA/RNA based therapeutics (expressed proteins) in blood/tissue.o Structure and conformational elucidation by native mass spectrometry and H/D exchange LC-MS.o Host cell and trace level of protein/enzyme impurity analysis.o Client interaction providing relevant expertise in pharmaceutical/scientific backgrounds
  • Northeastern University
    Professor
    Northeastern University Jul 2007 - Jan 2013
    Boston, Ma, Us
    • Development of LC-MS based proteomic approaches for analysis of various post-translational modification such as phosphorylation, glycostructures, and disulfide scrambling in samples from different disease stages.• Biomarker analysis in tissue cells captured by laser capture microdissection with LC-MS proteomic approaches (e.g., in breast and cervical cancer related disease stages). Further biomarker analysis in serum or plasma of patients with related disease stages.• Development of LC-MS approach for the study of pharmacokinetics and metabolism of protein drugs.
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  • Barnett Institute, Northeastern University
    Associate Professor
    Barnett Institute, Northeastern University 2003 - 2006
  • Thermo Fisher Scientific
    Application Manager
    Thermo Fisher Scientific Mar 2001 - Oct 2003
    Waltham, Ma, Us
    • Development of Ion-Trap with FTMS Mass Spectrometry technology for proteomics related applications. • Development of sample handling strategies to study the proteomics of cellular and tissue samples from laser capture microdissection to mass spectrometry.• Analysis of protein’s structures, phosphorylation modifications, and glycosylation from solution and gel spots by multi-dimensional LC with MS/MS. Designed and performed representative experiments for various customer samples.
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  • Scios / J & J
    Group Leader
    Scios / J & J 1997 - 2000
    • Developed formulation and manufacture process:o Identified the relation between melt back phenomenon and the glass transition temperature of sucrose formulation from related degradation pathway. o Identified the critical lyophilization conditions for a formulation through disulfide scrambling analysis.
  • Genentech
    Scientist And Group Leader
    Genentech 1987 - 1996
    South San Francisco, California, Us
    • Developed analytical characterization manufacture process:o Trouble-shoot of commercial therapeutic drug such as identified the cause of low clot lysis activity problem in CHO cell expressed system. Prepared the protein chemistry and analytical assay data for FDA submission (NDA amendment for process yield improvement). Verified the pharmacokinetic difference related to the modification of carbohydrate structure (using CE, CE-MS, Ion Chromatography, and LC with triple quadrupole and MALDI MS). Separation of structure variants by a new analytical HIC method.o Studied protein aggregation, protein-receptor, and protein-antibody (IgE and anti-IgE) binding phenomenon in solution using Low Angle Laser Light Scattering on-line coupling with HPLC. Discovered detergent-based hydrophobic interaction chromatography (HIC) as a new general method for membrane protein analysis and purification.
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Billy Wu Skills

Protein Chemistry Lc Ms

Billy Wu Education Details

  • Northeastern University, Boston, Ma
    Northeastern University, Boston, Ma
    Analytical Chemistry

Frequently Asked Questions about Billy Wu

What company does Billy Wu work for?

Billy Wu works for Bioanalytix, Inc.

What is Billy Wu's role at the current company?

Billy Wu's current role is Chief Scientific Officer.

What is Billy Wu's email address?

Billy Wu's email address is bw****@****inc.com

What is Billy Wu's direct phone number?

Billy Wu's direct phone number is +161737*****

What schools did Billy Wu attend?

Billy Wu attended Northeastern University, Boston, Ma.

What skills is Billy Wu known for?

Billy Wu has skills like Protein Chemistry, Lc Ms.

Who are Billy Wu's colleagues?

Billy Wu's colleagues are Erika Garside, Xiaomei (Annie) He, Annie He.

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