Bingfa Sun Email & Phone Number

Santa Clara, CA, US

Santa Clara, California, US

• Managing company’s R&D pipeline.
• Leading the company’s new target validation and launch effort.
• Leading the structural biology effort in collaboration with pharmaceutical partners.
• Leading the preparation of SBIR research proposal and budget management.
• Coordinating the work of computational medicinal chemistry, structural biology, pharmacology in company’s internal structure-based drug discovery effort.
• Establishing collaboration with CRO companies on medicinal chemistry and pre-clinical studies.

Santa Clara, California, US

• Managing the structure-based drug discovery, coordinating the work of computational medicinal chemistry, structural biology, pharmacology, and external medicinal chemistry and pre-clinical studies.
• Leading structural studies of GPCRs in complex with hit or lead compounds in active pipelines, with sufficient quality and turnaround time to facilitate drug discovery. More than 15 milestones have been achieved.
• Established negative-staining EM and cryo-EM capability in Confometrx.
• Redirected a stalled project leading to subsequent Phase II SBIR funding and identified novel hit compounds.
• Identification of disease indications of lead compounds for subsequent pre-clinical studies.

Santa Clara, California, US

• ConfometRx is developing a platform of structure-based drug development tools to facilitate target validation, lead identification, and lead optimization for G protein coupled receptor (GPCR) targets. Brian Kobilka.
• Solved Class A, B, C GPCR structures in their active- and inactive- states, coupled with G proteins, by X-ray crystallography.
• Solved Class A, B, C GPCR structures in their active-states, coupled with G proteins, by cryo-EM.
• Wrote and received NIH SBIR grants (Phase I and Phase II, Role: Principle Investigator

Doctor Of Philosophy (Ph.D.), Biochemistry

Bachelor'S Degree, Biology/Biological Sciences, General