Binod G C

Binod G C Email and Phone Number

Postdoctoral Associate @ Yale University
New Haven, CT, US
Binod G C's Location
Toledo, Ohio, United States, United States
About Binod G C

Dynamic and result-oriented Cell and Molecular Biologist with over 5 years of extensive experience in applying advanced techniques to study hematopoietic cell biology and transcription factor regulation. My research focuses on using molecular and bioinformatics tools to explore gene expression and regulation in normal hematopoiesis and hematological malignancies.

Binod G C's Current Company Details
Yale University

Yale University

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Postdoctoral Associate
New Haven, CT, US
Binod G C Work Experience Details
  • Yale University
    Postdoctoral Associate
    Yale University
    New Haven, Ct, Us
  • Department Of Molecular, Cellular, And Developmental Biology, University Of Toledo
    Graduate Research And Teaching Assistant
    Department Of Molecular, Cellular, And Developmental Biology, University Of Toledo Aug 2019 - Present
    Toledo, Ohio, United States
    ๐—š๐—ฅ๐—”๐——๐—จ๐—”๐—ง๐—˜ ๐—ฅ๐—˜๐—ฆ๐—˜๐—”๐—ฅ๐—–๐—› ๐—”๐—ฆ๐—ฆ๐—œ๐—ฆ๐—ง๐—”๐—ก๐—งProject: ๐Œ๐ž๐œ๐ก๐š๐ง๐ข๐ฌ๐ญ๐ข๐œ ๐ˆ๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐š๐ง๐ ๐›๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐จ๐Ÿ ๐†๐Ÿ๐ข๐Ÿ-๐Œ๐ž๐๐ข๐š๐ญ๐ž๐ ๐ฎ๐ฉ๐ซ๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐จ๐Ÿ ๐‡๐ž๐ฆ๐ ๐งโ€ข Demonstrated that Gfi1 upregulates Hemgn via a specific 16-bp promoter region, dependent on LSD1 interaction.โ€ข Discovered that PU.1 represses Hemgn and inhibits its upregulation by Gfi1; Gfi1's repression of PU.1 correlates with increased Hemgn.โ€ข Established that Hemgn upregulation contributes to Gfi1's anti-apoptotic function in a p53-independent manner.Project: ๐‘๐จ๐ฅ๐ž ๐จ๐Ÿ ๐†๐Ÿ๐ข๐Ÿ ๐ข๐ง ๐€๐ฉ๐จ๐ฉ๐ญ๐จ๐ฌ๐ข๐ฌ ๐‘๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐ง ๐ญ๐ก๐ซ๐จ๐ฎ๐ ๐ก ๐๐œ๐ฅ-๐ฑ๐‹ ๐”๐ฉ๐ซ๐ž๐ ๐ฎ๐ฅ๐š๐ญ๐ข๐จ๐งโ€ข Found that Gfi1 inhibits stress-induced apoptosis in response to DNA damage, growth factor withdrawal, and cytokine activation (TGFฮฒ, Myc).โ€ข Identified that Gfi1 upregulates the pro-survival Bcl-2 family member Bcl-xL independently of p53, enhancing cell survival through Gfi1 mediated upregulation of Hemgn.๐—ง๐—˜๐—”๐—–๐—›๐—œ๐—ก๐—š ๐—”๐—ฆ๐—ฆ๐—œ๐—ฆ๐—ง๐—”๐—ก๐—งโ€ข ๐Œ๐ข๐œ๐ซ๐จ๐›๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐‹๐š๐› (๐๐ˆ๐Ž๐‹๐Ÿ’๐ŸŽ๐Ÿ’๐ŸŽ): Emphasizes basic microbiological techniques aligned with American Society for Microbiology guidelines. Covers methods for isolating, culturing, and identifying microorganisms, studying their biochemical, genetic, and molecular properties, and exploring approaches to control. Practical training for clinical and research labs. Guiding lab work, demonstrating, grading, and overseeing the procedure.โ€ข ๐…๐ฎ๐ง๐๐š๐ฆ๐ž๐ง๐ญ๐š๐ฅ๐ฌ ๐จ๐Ÿ ๐‹๐ข๐Ÿ๐ž ๐’๐œ๐ข๐ž๐ง๐œ๐ž๐ฌ ๐‹๐š๐› (๐๐ˆ๐Ž๐‹ ๐Ÿ๐Ÿ๐Ÿ–๐ŸŽ): Basic metabolic, photosynthetic, biological transport, and enzyme activity mechanisms were taught and demonstrated. Quizzes, workbooks, lab reports, and lab practical tests were all graded.โ€ข ๐…๐ฎ๐ง๐๐š๐ฆ๐ž๐ง๐ญ๐š๐ฅ๐ฌ ๐จ๐Ÿ ๐‹๐ข๐Ÿ๐ž ๐’๐œ๐ข๐ž๐ง๐œ๐ž๐ฌ ๐‹๐š๐› (๐๐ˆ๐Ž๐‹ ๐Ÿ๐Ÿ๐Ÿ”๐ŸŽ): Vertebrate and invertebrate anatomy and physiology were taught and shown. Quizzes, workbooks, lab reports, and lab practical tests were all graded.
  • Kathmandu Research Institute For Biological Sciences (Kribs)
    Advisory Board Member/ Founding Member
    Kathmandu Research Institute For Biological Sciences (Kribs) 2016 - Present
    Kathmandu, Bฤgmatฤซ, Nepal
    2016-2019: Research Faculty
  • The Science Notes
    Founder / Blogger
    The Science Notes Mar 2018 - Present
    Kathmandu, Bฤgmatฤซ, Nepal
    In my capacity as a Founder, Editor, and writer of the โ€œ https://thesciencenotes.com โ€, I create and curate high quality content, manage the overall direction and strategy of the site, to promote scientific literacy and understanding.
  • International Friendship Children'S Hospital
    Microbiologist
    International Friendship Children'S Hospital Jan 2017 - May 2018
    Kathmandu, Bฤgmatฤซ, Nepal
    โ€ข Microbial cultureโ€ข Antibiotic susceptibility testingโ€ข Microbial genomics

Binod G C Education Details

Frequently Asked Questions about Binod G C

What company does Binod G C work for?

Binod G C works for Yale University

What is Binod G C's role at the current company?

Binod G C's current role is Postdoctoral Associate.

What schools did Binod G C attend?

Binod G C attended The University Of Toledo, Tribhuvan University, Tribhuvan University.

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