Dynamic and result-oriented Cell and Molecular Biologist with over 5 years of extensive experience in applying advanced techniques to study hematopoietic cell biology and transcription factor regulation. My research focuses on using molecular and bioinformatics tools to explore gene expression and regulation in normal hematopoiesis and hematological malignancies.
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Postdoctoral AssociateYale UniversityNew Haven, Ct, Us -
Graduate Research And Teaching AssistantDepartment Of Molecular, Cellular, And Developmental Biology, University Of Toledo Aug 2019 - PresentToledo, Ohio, United States๐๐ฅ๐๐๐จ๐๐ง๐ ๐ฅ๐๐ฆ๐๐๐ฅ๐๐ ๐๐ฆ๐ฆ๐๐ฆ๐ง๐๐ก๐งProject: ๐๐๐๐ก๐๐ง๐ข๐ฌ๐ญ๐ข๐ ๐๐ง๐ฌ๐ข๐ ๐ก๐ญ๐ฌ ๐๐ง๐ ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐จ๐ ๐๐๐ข๐-๐๐๐๐ข๐๐ญ๐๐ ๐ฎ๐ฉ๐ซ๐๐ ๐ฎ๐ฅ๐๐ญ๐ข๐จ๐ง ๐จ๐ ๐๐๐ฆ๐ ๐งโข Demonstrated that Gfi1 upregulates Hemgn via a specific 16-bp promoter region, dependent on LSD1 interaction.โข Discovered that PU.1 represses Hemgn and inhibits its upregulation by Gfi1; Gfi1's repression of PU.1 correlates with increased Hemgn.โข Established that Hemgn upregulation contributes to Gfi1's anti-apoptotic function in a p53-independent manner.Project: ๐๐จ๐ฅ๐ ๐จ๐ ๐๐๐ข๐ ๐ข๐ง ๐๐ฉ๐จ๐ฉ๐ญ๐จ๐ฌ๐ข๐ฌ ๐๐๐ ๐ฎ๐ฅ๐๐ญ๐ข๐จ๐ง ๐ญ๐ก๐ซ๐จ๐ฎ๐ ๐ก ๐๐๐ฅ-๐ฑ๐ ๐๐ฉ๐ซ๐๐ ๐ฎ๐ฅ๐๐ญ๐ข๐จ๐งโข Found that Gfi1 inhibits stress-induced apoptosis in response to DNA damage, growth factor withdrawal, and cytokine activation (TGFฮฒ, Myc).โข Identified that Gfi1 upregulates the pro-survival Bcl-2 family member Bcl-xL independently of p53, enhancing cell survival through Gfi1 mediated upregulation of Hemgn.๐ง๐๐๐๐๐๐ก๐ ๐๐ฆ๐ฆ๐๐ฆ๐ง๐๐ก๐งโข ๐๐ข๐๐ซ๐จ๐๐ข๐จ๐ฅ๐จ๐ ๐ฒ ๐๐๐ (๐๐๐๐๐๐๐๐): Emphasizes basic microbiological techniques aligned with American Society for Microbiology guidelines. Covers methods for isolating, culturing, and identifying microorganisms, studying their biochemical, genetic, and molecular properties, and exploring approaches to control. Practical training for clinical and research labs. Guiding lab work, demonstrating, grading, and overseeing the procedure.โข ๐ ๐ฎ๐ง๐๐๐ฆ๐๐ง๐ญ๐๐ฅ๐ฌ ๐จ๐ ๐๐ข๐๐ ๐๐๐ข๐๐ง๐๐๐ฌ ๐๐๐ (๐๐๐๐ ๐๐๐๐): Basic metabolic, photosynthetic, biological transport, and enzyme activity mechanisms were taught and demonstrated. Quizzes, workbooks, lab reports, and lab practical tests were all graded.โข ๐ ๐ฎ๐ง๐๐๐ฆ๐๐ง๐ญ๐๐ฅ๐ฌ ๐จ๐ ๐๐ข๐๐ ๐๐๐ข๐๐ง๐๐๐ฌ ๐๐๐ (๐๐๐๐ ๐๐๐๐): Vertebrate and invertebrate anatomy and physiology were taught and shown. Quizzes, workbooks, lab reports, and lab practical tests were all graded. -
Advisory Board Member/ Founding MemberKathmandu Research Institute For Biological Sciences (Kribs) 2016 - PresentKathmandu, Bฤgmatฤซ, Nepal2016-2019: Research Faculty -
Founder / BloggerThe Science Notes Mar 2018 - PresentKathmandu, Bฤgmatฤซ, NepalIn my capacity as a Founder, Editor, and writer of the โ https://thesciencenotes.com โ, I create and curate high quality content, manage the overall direction and strategy of the site, to promote scientific literacy and understanding. -
MicrobiologistInternational Friendship Children'S Hospital Jan 2017 - May 2018Kathmandu, Bฤgmatฤซ, Nepalโข Microbial cultureโข Antibiotic susceptibility testingโข Microbial genomics
Binod G C Education Details
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Cell/Cellular And Molecular Biology -
Microbiology, General
Frequently Asked Questions about Binod G C
What company does Binod G C work for?
Binod G C works for Yale University
What is Binod G C's role at the current company?
Binod G C's current role is Postdoctoral Associate.
What schools did Binod G C attend?
Binod G C attended The University Of Toledo, Tribhuvan University, Tribhuvan University.
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