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I’m a researcher interested in developing methods through synthetic biology and chemical ecology approaches for sustainable insect pest management. I hold a Ph.D. in Biological Sciences, with over 15 years of research experience in entomology, chemical ecology, functional genomics, and synthetic biology. My research experience in RNAi, functional genomics (multi-omics, heterologous expression, etc.), high-throughput sequencing and analyses, transgenics, functional characterization of genes, electrophysiology, and cell culture. From 2012 until Sept 2023, I worked at King Saud University-Riyadh and led a research group on chemical ecology and functional genomics. My research specialized in functional characterizing insect pheromone biosynthesis genes and engineering to produce pheromones in microbial systems. We demonstrated the pivotal role of the pheromone gland-specific fatty acyl-CoA reductases (pgFAR) and an E12 desaturase in making species-specific signals in moths, genetically engineering yeast and incorporating these biobricks to produce cost-effective pheromone bioproduction. Our research targeting chemoreceptor proteins involved in odorant detection insects was demonstrated using an RNAi knockdown of OR-Orco, and it proposed that disrupting chemical communication would be a promising approach for controlling insect pests. Combining OMICS-driven approaches, including RNAseq, loss-of-function through RNAi, and Drosophila expression, we have characterized the first RPW pheromone receptor and a kairomone receptor. We concluded a research project on developing OR-OBP-based biosensors for the early detection of palm weevil infestation in the date palm field. Key publications:-Insect Biochem Mol Biol (2024) https://doi.org/10.1016/j.ibmb.2024.104129 -Annual Rev Entomol (2024) https://doi.org/10.1146/annurev-ento-013023-121139 -Pest Manag Sci (2022) https://doi.org/10.1002/ps.6716-Molecular Ecology (2021) https://doi.org/10.1111/mec.15874 -Sci Rep (2020) https://www.nature.com/articles/s41598-021-87348-y-BMC Genomics (2019) https://doi.org/10.1186/s12864-019-5837-4 -Frontiers in Physiol (2018) https://doi.org/10.3389/fphys.2018.00252-Insect Mol Biol (2017) https://doi.org/10.1111/imb.12314 -Sci Rep (2016) https://doi.org/10.1038/srep29927-BMC Genomics (2016) https://doi.org/10.1186/s12864-016-2362-6 -BMC Genomics (2015) https://doi.org/10.1186/s12864-015-1710-2 -PNAS USA (2013) https://doi.org/10.1073/pnas.120870611-Nature (2010) https://doi.org/10.1038/nature09058 -Insect Biochem Mol Biol (2009) https://doi.org/10.1016/j.ibmb.2008.10.008
United Arab Emirates University
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Expert And Associate Professor (Research)United Arab Emirates UniversityKochi, Kl, In
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Adjunct Associate ProfessorKing Saud University Sep 2023 - PresentRiyadh, Saudi ArabiaResearch Output: https://doi.org/10.1146/annurev-ento-013023-121139https://authors.elsevier.com/a/1j4QB3RT96XznQMy role focused on designing and conducting experiments, analyzing data, and presenting findings to internal and external stakeholders/collaborators/funders, developing grant applications, establishing and leading a research lab/group, initiating academic and private collaborations, and conducting research and extension programs at the Chair of Date Palm Research. I supervise research activities and develop and implement externally funded research projects at the Center for Chemical Ecology and Functional Genomics (chair of date palm research). Besides, I’m leading the project work funding through IFKSUDR (Jan 2023 - Dec 2004) entitled “Developing biohybrid cell-free pheromone receptor-based sensor to monitor the destructive date palm tree pest, the red palm weevil, Rhynchophorus ferrugineus, in the date plantations of Saudi Arabia.” -
Associate ProfessorKing Saud University Aug 2019 - Sep 2023Riyadh, Saudi ArabiaResearch output:https://doi.org/10.1111/mec.15874https://doi.org/10.1038/s41598-021-87348-yhttps://www.frontiersin.org/articles/10.3389/fevo.2023.1159142/fullhttps://doi.org/10.1002/ps.6716DOI: 10.17660/ActaHortic.2023.1371.21https://www.frontiersin.org/articles/10.3389/fevo.2023.1159142/fullhttps://doi.org/10.1101/2023.01.13.523742 https://doi.org/10.1146/annurev-ento-013023-121139My research prioritizes developing eco-friendly green chemistry solutions for managing an invasive pest, the red palm weevil (RPW), Rhynchophorus ferrugineus. We run two major grants on developing olfactory protein-based biosensors, genome engineering, and olfactory communication disruption. We achieved a key milestone in unraveling the molecular basis of olfaction R. ferrugineus. We identified the chemosensory gene family proteins involved in odorant detection from R. ferrugineus (Antony et al., 2016). We demonstrated using an RNAi technique to knock down olfactory gene expression (Soffan et al., 2016). We proposed that disrupting the palm weevil olfactory system had been a promising approach for controlling this pest. We identified the Odorant binding protein (OBP) specific to the aggregation pheromone ferrugineol of RPW (RferOBP1768). We demonstrated that the RferOBP1768 gene can be silenced with RNAi, leading to pheromone anosmia, thereby providing a solid baseline for further development of palm weevil management programs (Antony et al., 2018). By a combination of OMICS-driven approaches, including RNAseq, loss-of-function through RNAi, and transgenic (Drosophila) expression methods, we have characterized the very first RPW pheromone receptor (RferOR1) (Antony et al., 2021). The discovery of the pheromone receptor won the prestigious Khalifa International Award for Date Palm and Agricultural Innovation 2022 - Distinguished Innovative Studies and Modern Technology. We characterized an odorant receptor tuned to several ecologically relevant palm-emitted odors.
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Assistant ProfessorKing Saud University Jan 2012 - Aug 2019Al-Riyadh Governorate, Saudi ArabiaResearch output:https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-015-1710-2https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2362-6https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162203 https://resjournals.onlinelibrary.wiley.com/doi/10.1111/imb.12314https://www.frontiersin.org/articles/10.3389/fphys.2018.00252/full https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-019-5837-4
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Assistant ProfessorCentral University Of Kerala Nov 2011 - Jan 2012Kasaragod, Kerala, IndiaTeaching/Research Supervision:-Cell and Molecular Biology-Applied insect science – pest management-Evolutionary biology - Molecular evolution, Evolution of behaviour, Phylogeny and Molecular markers.-Administrative Assignment/main supervisor for an MPhil program. Project title: "Identification and screening of expression sequence tags EST of pheromone gland FAR in Helicoverpa armigera".Writing, reviewing, and editing the manuscript/thesis. -
Assistant ProfessorChrist College (Autonomous),Irinjalakuda Oct 2010 - Nov 2011Teaching/ Research Supervision at Christ College, Kerala, India-First Semester B. Sc. Zoology Course Code: ZO1B01 (General Methodology and Perspectives in Science).-Fourth Semester B.Sc. Zoology Code: ZO3B05 (General and Bioinformatics).-Fourth Semester B.Sc. Zoology Code: ZO4B07 (Ethology and Evolution). -Fourth Semester B.Sc. Zoology Code: ZO5B10 Core Course VI (Cell Biology, Genetics & Molecular Biology).-First Semester, MSc. Zoology (Code: ZO 1-CT-03), Systematics and Evolution.-Second Semester M. Sc. Zoology (code: ZO 2-CT-04), Physiology. -Third Semester M.Sc. Zoology (Code: ZO-3-CT-07), Molecular Biology.Main Supervisor. 2009-2010 Kavitha, S (M.Sc Zoology). Thesis: Metabolic and histopathological effects of dimethoate on Cyprinus carpio carpio. Christ College (affiliated to Calicut University), India. -
Research Entomologists (Scientist C)Tea Research Association (Tra Tocklai) Jul 2009 - Sep 2010Jorhat, Assam, IndiaResearch output:https://www.sciencedirect.com/science/article/abs/pii/S0022201111001133?via%3Dihubhttps://www.tandfonline.com/doi/abs/10.1080/03235408.2013.845469https://hortherbpublisher.com/index.php/jtsr/article/view/467https://doi.org/10.1017/S174275841100035Xhttps://doi.org/10.1080/09583157.2011.588999As a Research entomologist (Tea Research Association, India), I was a lead researcher in the tea pest entomology research program. Our task was to develop and deliver updated information on arthropod pest management for tea crops in the Northeastern Indian states of Assam and West Bengal (the largest tea-growing region globally). I worked closely with several tea garden extension scientists and cooperative extension teams in Assam's four major tea-growing areas (Cachar, North Bank, South Bank, and Upper Assam). Our team is dedicated to highlighting an important, newly emerged major pest of tea, commonly known as tea looper caterpillars: Biston spp. and Hyposidra spp. In early 2000, Looper caterpillars emerged as severe pests of tea, and at least four species were found to invade the entire tea-growing belt of northeast India. Sometimes, mixed broods appear in various tea gardens in Assam. We proposed several new initiatives to tackle the looper problem and supportive evidence that the situation of a looper outbreak resulted from climate change in northeast India (Antony et al., 2012). Through field extension activities, we reported a very appealing note that the beginning of this century was marked by the increased report of looper invasion, and in the last two years, looper attacks have been reported from almost all Assam and North Bengal tea gardens. We reported novel nucleopolyhedrosis virus (NPV) infecting loopers (Antony et al., 2011), proposed new biopesticides, and prompted the tea industry and practitioners to adopt the microbial management of loopers.
Binu Antony Skills
Binu Antony Education Details
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Http://Hdl.Handle.Net/10603/170731 (Thesis Repository) -
Chemical Ecology/Biotechnology -
Chemical Ecology/Biotechnology -
Researcher, Japanese Government (Monbukagakusho/Mext) Scholarship.
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A' Grade
Frequently Asked Questions about Binu Antony
What company does Binu Antony work for?
Binu Antony works for United Arab Emirates University
What is Binu Antony's role at the current company?
Binu Antony's current role is Expert and Associate Professor (Research).
What is Binu Antony's email address?
Binu Antony's email address is bi****@****o.co.in
What schools did Binu Antony attend?
Binu Antony attended University Of Kerala, Lunds Universitet / Lund University, 東京大学 / The University Of Tokyo, The University Of Tokyo, University Of Kerala.
What skills is Binu Antony known for?
Binu Antony has skills like Microsoft Office, Microsoft Excel, Microsoft Word, Powerpoint, Customer Service.
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