Buckley Kohlhauff Email & Phone Number

Colorado Springs, Co, Us

Colorado Springs, Colorado, United States

Information Technology solutions and project implementations

Responsible for direction of IT operations at FivePrime, a clincal-stage biotechnology company focused on engineered protein based therapeutics (fusions, chimerics, mAb, secretory, high affinity ligand traps)

Direct the design, implementation, and support of corporate information systems. Acquire and refresh technology architecture, infrastructure, and processes to support business objectives and regulatory requirements.• Re-engineer software product line to use J2EE architecture. Improve documentation and programming APIs to allow for licensing to state and federal governments.• Establish goals, objectives, and policies for business analysts and software engineers to redesign corporate back office operations. Report operational results to executive management, auditors, and board of directors.• Designed and implemented a $3M cost-savings plan to reduce operational expenditures in the data center and administrative functions.• Prepared strategic and tactical restructuring plans as part of a transition task force.• Customized off the shelf applications to support clinical trials, clinical data, and document management according to the Code of Federal Regulation guidelines.

Direct the design and implementation of information systems utilized for drug discovery, including target discovery, target validation, high-throughput screening, and lead optimization. • Responsible for the supervision and direction of computational biology, application development, high performance computing, technology integration, project management, and process support. With a staff of over 40 individuals and an annual budget of $7M.• Successfully launched 3 web-based database applications that have generated over $30M in revenue.• Provide applications and equipment to support operations for over 350 scientists.• Worked with Finance to integrate JDE Financial ERP system in with LIMS/MRP systems and Augeo IP Project Management software.• Successfully utilized computational methods to perform early target validation of over 5,000 pharmaceutically relevant genes.• Engineered a high performance computing center with Linux clusters for sequence analysis.

• Responsible for the design and implementation of a sequence analysis and LIMS system.• Managed Bioinformatics associates and scientists and software engineers; Java, PHP, CVS, Tomcat, Apache. Implemented software development methodologies RUP and worked on reaching CMM level 1-3.• Managed database systems for storing genomics data from public and proprietary data sources; MySQL, ASN, EMBL, Sybase, Oracle• Developed and managed tools for genomics data analysis; BLAST, HMMER, PFAM, GenBank, Derwent, Spotfire, GCG, Sequencher, R

• Managed the HARC data center, including several large disk arrays and 2 NEC supercomputers.• Designed, purchased, and implemented a site-wide back-up strategy.• Designed and managed a cluster of SGI Origin Unix servers for geophysical data visualization and analysis.• Managed batch submission jobs for superconductivity experiments.• Worked on a database for a microarray chip for the detection of HPV in the molecular diagnostics lab.

• Lead Systems Engineer for UTMB outsourcing project.• Performed network security audit and Internet/Extranet design for UTMB Galveston campus and satellite sites.• Managed Novell/NT migration at UTMB main campus.• Assisted in design and deployment of remote medical station for aiding clinical staff on oil rigs and remote locations using IP videoconferencing.• Wrote Web-based apps (CGI using C) for legacy application access through Apache web server.

• Managed Unix Systems and scientific software applications ; GCG, Pangea (Doubletwist)• Maintained web server administered and programmed pages, set-up network and security.

Computer Science

Activities and Societies: Sigma Tau Gamma, ROTC

Education record

Computer Science