Buckley Kohlhauff Email & Phone Number

Colorado Springs, CO, US

Colorado Springs, Colorado, United States

Information Technology solutions and project implementations

Responsible for direction of IT operations at FivePrime, a clincal-stage biotechnology company focused on engineered protein based therapeutics (fusions, chimerics, mAb, secretory, high affinity ligand traps)

• Direct the design, implementation, and support of corporate information systems. Acquire and refresh technology architecture, infrastructure, and processes to support business objectives and regulatory requirements.
• Re-engineer software product line to use J2EE architecture. Improve documentation and programming APIs to allow for licensing to state and federal governments.
• Establish goals, objectives, and policies for business analysts and software engineers to redesign corporate back office operations. Report operational results to executive management, auditors, and board of directors.
• Designed and implemented a $3M cost-savings plan to reduce operational expenditures in the data center and administrative functions.
• Prepared strategic and tactical restructuring plans as part of a transition task force.
• Customized off the shelf applications to support clinical trials, clinical data, and document management according to the Code of Federal Regulation guidelines.

• Direct the design and implementation of information systems utilized for drug discovery, including target discovery, target validation, high-throughput screening, and lead optimization.
• Responsible for the supervision and direction of computational biology, application development, high performance computing, technology integration, project management, and process support. With a staff of over 40.
• Successfully launched 3 web-based database applications that have generated over $30M in revenue.
• Provide applications and equipment to support operations for over 350 scientists.
• Worked with Finance to integrate JDE Financial ERP system in with LIMS/MRP systems and Augeo IP Project Management software.
• Successfully utilized computational methods to perform early target validation of over 5,000 pharmaceutically relevant genes.

• Responsible for the design and implementation of a sequence analysis and LIMS system.
• Managed Bioinformatics associates and scientists and software engineers; Java, PHP, CVS, Tomcat, Apache. Implemented software development methodologies RUP and worked on reaching CMM level 1-3.
• Managed database systems for storing genomics data from public and proprietary data sources; MySQL, ASN, EMBL, Sybase, Oracle
• Developed and managed tools for genomics data analysis; BLAST, HMMER, PFAM, GenBank, Derwent, Spotfire, GCG, Sequencher, R

• Managed the HARC data center, including several large disk arrays and 2 NEC supercomputers.
• Designed, purchased, and implemented a site-wide back-up strategy.
• Designed and managed a cluster of SGI Origin Unix servers for geophysical data visualization and analysis.
• Managed batch submission jobs for superconductivity experiments.
• Worked on a database for a microarray chip for the detection of HPV in the molecular diagnostics lab.

• Lead Systems Engineer for UTMB outsourcing project.
• Performed network security audit and Internet/Extranet design for UTMB Galveston campus and satellite sites.
• Managed Novell/NT migration at UTMB main campus.
• Assisted in design and deployment of remote medical station for aiding clinical staff on oil rigs and remote locations using IP videoconferencing.
• Wrote Web-based apps (CGI using C) for legacy application access through Apache web server.

• Managed Unix Systems and scientific software applications; GCG, Pangea (Doubletwist)
• Maintained web server administered and programmed pages, set-up network and security.

Computer Science

Activities and Societies: Sigma Tau Gamma, ROTC

Education record

Computer Science