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Built startup from founding (2015) to 130 employees with multiple assets, and raised >$800M (equity + partnerships). Completed successful IPO (2019) followed by company acquisition by Lilly for $3.2B (2024). Proven track record advancing molecules to clinical trials, including the approved drug Daurismo/ Glasdegib for leukemia. Experienced in multiple disease areas (oncology, immunology, pain, antibacterials, IBD, fibrosis), and target types (kinase, GPCR, ion channel, PPI, protease). Member of early and late stage clinical development teams (IND -> NDA -> commercialization). Motivated and goal-oriented leader adept at working both in startups and large pharma environments. Proven experience in creating new companies, crisp decision making, introducing innovative technologies, and developing people as scientists and managers.
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CxoCurie.BioNewton, Ma, Us -
Chief Scientific OfficerMorphic Therapeutic May 2022 - PresentWaltham, Ma, Us• Leading all research and translational sciences at Morphic (56 FTEs)• Responsible for multiple therapeutic areas (Immunology, Fibrosis, PAH, Oncology), and scientific disciplines (Biology, Translational, Structural Biology, Bioinformatics, Chemoinformatics and Medicinal Chemistry) -
Sr. Vice President Of Molecular DiscoveryMorphic Therapeutic Feb 2020 - May 2022Waltham, Ma, Us• Leading all Molecular Discovery at Morphic, including Structural Biology, Antibody Discovery, Chemistry, Computational Modeling and Biological Screening• Responsible for protein expression, purification, crystallization and solving complex structures• Overseeing antibody discovery efforts, including hybridoma and phage display -
Vice President, ChemistryMorphic Therapeutic Jun 2015 - Feb 2020Waltham, Ma, Us• Responsible for hiring research team from founding, and initiating multiple integrin projects• Leadership role for Schrödinger partnership, and other CRO/ CDMOs -
Sab MemberProteinqure Nov 2018 - PresentToronto, Ontario, Ca -
Senior Director Of Medicinal ChemistryCubist Pharmaceuticals Dec 2011 - May 2015Lexington, Ma, Us• Co-leader of Cubist Medicinal Chemistry Department (26 FTEs)• Led efforts advancing antibacterial, pain and acute care projects to the clinic with multi-disciplinary project teams • Won 2011 Cubist Employee of the Year, and Team of the Year (as team leader) awards • Member of Ceftolozane/ Tazobactam (Zerbaxa®) development core team during advanced clinical trials, NDA submission, and market positioning -
DirectorCubist Pharmaceuticals Apr 2008 - Nov 2011Lexington, Ma, Us• Led a group of 12 chemists directly (4 Ph.D., 8 B.S./M.S.)• Project team leader for multiple projects in the pain and antibacterial therapeutic areas; capable of leading 3 large projects simultaneously (> 50 internal FTEs)• Key leader of external collaborations, including Heptares (GPCR structural biology) and Hydra (ion channels) -
Senior Principal ScientistPfizer Jan 2006 - Mar 2008New York, New York, Us• Lead medicinal chemistry designer in the metabolic disease therapeutic area (2007-2008)• Advanced projects for diabetes, frailty, and osteoporosis• Lead medicinal chemistry designer in the antibacterials therapeutic area (2006-2007) -
Principal ScientistPfizer Jan 2002 - Dec 2005New York, New York, Us• Project team leader of AKT oncology project with > 20 FTEs (chemistry, biology, computational chemistry, PK, toxicology, and pharm. sci.). Conceived the crucial molecular design that led to high kinase selectivity and efficacy. Successively achieved a development candidate on schedule for human clinical trials• Conceived and advanced an idea for a novel exploratory project targeting tumor stem cells (Hedgehog pathway/ Smo). Successfully advocated for project launch and led initial team. Compound ultimately FDA approved (Daurismo/ Glasdegib) for leukemia -
Senior ScientistPfizer Dec 1999 - Dec 2001New York, New York, Us• Initiated a global kinase selectivity panel leading to a Pfizer Recognition Award• Advanced multiple oncology projects in Discovery
Blaise Lippa Skills
Blaise Lippa Education Details
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Stanford UniversityOrganic Chemistry -
University Of MichiganChemistry And Cellular Molecular Biology -
University Liggett School
Frequently Asked Questions about Blaise Lippa
What company does Blaise Lippa work for?
Blaise Lippa works for Curie.bio
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Blaise Lippa's current role is CXO.
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What is Blaise Lippa's direct phone number?
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What schools did Blaise Lippa attend?
Blaise Lippa attended Stanford University, University Of Michigan, University Liggett School.
What skills is Blaise Lippa known for?
Blaise Lippa has skills like Drug Discovery, Medicinal Chemistry, Drug Design, Drug Development, Organic Chemistry, Lead Change, Life Sciences, High Throughput Screening, Cheminformatics, Adme, Project Leadership, Portfolio Management.
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