Bob Sacchiero Email and Phone Number
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Experienced senior scientist in drug discovery and development with 22 years experience in the Biopharmaceutical Industry. Background in all aspects of preclinical research using in vitro and in vivo model systems to study disease biology and target validation. Knowledge of all aspects of pharmacology and some areas of toxicology. Many lessons learned in "translational biology" with experience in mice, rats, hamsters, guinea pigs, dogs, pigs and monkeys.Scientific leadership experience on a variety of strategic and decision-making groups with both internal and external organizations. Excellent organizational, communication and mentoring skills with management experience at a variety of levels. Proven record of success in creating, developing and utilizing animal models of disease that "translated" to success for 5 drugs that met human clinical efficacy endpoints and 3 of which are marketed worldwide with sales exceeding $1 billion annually.Experience with a variety of therapeutic approaches including small molecule, non-absorbed polymers, proteins and gene therapy. Extensive background in biochemistry and physiology with an in depth knowledge in lipid and glucose metabolism, sphingolipid biology, GI physiology, renal physiology, fibrosis, inflammation and oxidative stress.My Goal: To join a company with a clear vision and viable strategy, committed to bringing transformational therapies to patients, where I can utilize my unique and valuable experiences in a productive, focused and rewarding environment.
Glyscend Incorporated
View- Website:
- glyscend.com
- Employees:
- 9
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Glyscend IncorporatedWaltham, Ma, Us
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Independent ConsultantGlyscend Incorporated Apr 2015 - PresentLowell, Massachusetts, UsGLYSCEND, INC., 855 NORTH WOLFE STREET, BALTIMORE, MD, 21205 Providing strategic and practical guidance for proof of concept studies in preclinical models of Type 2 Diabetes. Ongoing consultation through Glyscend incubator sites at Johns Hopkins University and University of Alabama
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Senior ScientistGenzyme, A Sanofi Company Mar 2011 - Mar 2015Paris, France, FrLed discovery research efforts in Rare Diseases including Fabry and X-Linked Adrenoleukodystrophy• Designed research strategies to better understand disease biology• Developed tools to study glycosphingolipid transport and partitioning in lipoproteins and tissues• Studied small molecules and biologics in the context of rodent disease models• Led cross-functional groups to validate drug targets and develop biomarkers of disease• Supervised and mentored scientists in preclinical pharmacology and discovery research• Served as a member of the IACUC board• Contributed significantly to analysis, interpretation and presentation of data• Communicated internally and externally through abstracts, presentations and manuscripts -
Staff Scientist 2 - Senior ScientistGenzyme 2001 - 2011Paris, France, FrDeveloped an in depth understanding in a variety of disease areas including; Renal, Diabetes, Obesity and Cardiovascular• Designed and managed research strategies in Discovery and Preclinical • Helped develop research collaborations with leading academic groups worldwide in Renal Disease• Developed animal models to study disease biology and MOA of therapies • Designed acute screening models as well as prevention and progression models• Managed scientists at a variety of levels with continued training in leadership and management• Presented research at national and international conferences and prepared manuscripts for publication
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Supervisor Of Animal Research - Staff Scientist 1Geltex 1993 - 2001Responsible for all aspects of preclinical in vivo biology, target validation and screening models• Experience with design of animal research facility in startup environment• Created and adapted in vitro and in vivo models to study non-absorbed polymeric therapeutics• Gained extensive experience across a wide range of animal species• Developed an in depth knowledge of comparative anatomy and physiology• Responsible for study design, data analysis, interpretation and presentation • Prepared abstracts, manuscripts and contributed to regulatory filings
Bob Sacchiero Skills
Bob Sacchiero Education Details
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University Of Massachusetts LowellBiochemistry -
University Of Massachusetts LowellPsychology
Frequently Asked Questions about Bob Sacchiero
What company does Bob Sacchiero work for?
Bob Sacchiero works for Glyscend Incorporated
What is Bob Sacchiero's role at the current company?
Bob Sacchiero's current role is Senior Scientist, Preclinical Pharmacology and Drug Discovery.
What is Bob Sacchiero's email address?
Bob Sacchiero's email address is bo****@****yme.com
What is Bob Sacchiero's direct phone number?
Bob Sacchiero's direct phone number is +150827*****
What schools did Bob Sacchiero attend?
Bob Sacchiero attended University Of Massachusetts Lowell, University Of Massachusetts Lowell.
What skills is Bob Sacchiero known for?
Bob Sacchiero has skills like Animal Models, Biotechnology, Drug Discovery, Life Sciences, Pharmacology, Assay Development, In Vivo, Drug Development, Biopharmaceuticals, In Vitro, Physiology, Molecular Biology.
Who are Bob Sacchiero's colleagues?
Bob Sacchiero's colleagues are Sai Sudha Chandan Bongu, Christine Bryant, Phd, Kevin Colbert.
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