Biortus Biosciences: Drug Target Recombinant Protein (soluble proteins and membrane proteins) Supplier, One Stop Structural Biology (X-ray crystallography, MicroED, Cryo-EM, Assay development and screening) CRO. The subsidiaries Biortus USA, Inc. serves as the headquarters for off-the-shelf Protein Catalogue and provides services for two way sample shipping and receiving, U.S domestic and international. • Managed logistics and daily operation of the Biortus USA site. -- Managed client/customer samples imports/exports, room temperature logistics, and cold chain logistics. -- Constant communication with clients for shipping/receiving updates, and issues resolution. -- Maintained relationships with key logistics, operational, and other companies. -- Purchased and installed all the office/lab supplies/fixed assets for operation • Managed company website development and digital marketing efforts -- Built, administered, and promoted Biortus USA Website (www.biortusUSA.com) -- Built and managed company business profiles on Google Profile, Facebook, Twitter, and Instagram. -- Managed and optimized website performance and content using web analytics and reporting tools. -- Developed, managed, and monitored digital marketing channels including company blogs, search engine optimization (SEO), and email marketing. • Assisted with catalog protein sales team -- Managed two -80C freezers and accessories, and catalog protein USA inventory. -- Sales backend support – Received PO; Packaging; Protein Shipment (US domestic and international, direct sales and various sale channels); Generated catalog protein invoices. -- Sales frontend support - Responded to customer inquiries and requests, Generated Quotation. • QuickBooks Online company administrator -- Implemented inventory management, customer management, time management, invoice management, and other modules for company operations.

For over 20 years, Velico has been focused on developing innovative blood and plasma products for transfusion. Velico has focused on improving the usability, accessibility, and shelf life of specialized blood products. Velico’s mission is to reduce the number of preventable deaths caused by bleeding significantly. • Spray-dried human blood and plasma product development, disposable and Frontline ODP™ technology evaluation. • Developed preclinical test protocols and reports, designed R&D experiments, and analyzed large data sets to evaluate the quality and performance of spray-dried plasma.

Adello biologics (Acquired by Kashiv BioSciences) is a fully-integrated biopharmaceutical company with global R&D, clinical, regulatory, and manufacturing capabilities. The company was originally formed as a specialty pharmaceutical business and has since transformed itself to develop and deploy its end-to-end biosimilars platform and aggressively expand its pipeline, including cytokines and monoclonal antibodies. In the first half of 2022, Kashiv validated its biosimilars platform after receiving FDA approvals for RELEUKO® (biosimilar to NEUPOGEN®) and FYLNETRA® (biosimilar to NEULASTA®). • Developed single-use bioreactor technology platform for microbial (E.Coli.) fermentation and mammalian (CHO) cell culture for Cytokine and Monoclonal Antibody (mAbs) production. -- Designed bioreactor bags and bioreactor characterization (mixing, mass transfer kLA) studies. -- Evaluated single-use components (such as pH, DO sensors) and equipment (such as glucose monitoring and controller) with vendors, sample testing for demonstration and sourcing. • Executed Fed-Batch and Perfusion cell culture experiments within the upstream process development group to support process scale-up (150 L for bacterial and 500 L for mammalian) and validation. • Partnered with IP group for prototype building and assessed novel ideas on mAbs clarification process. • Performed statistical data analysis, and process capability analysis for process and product data • Performed exploratory description, range testing, and equivalence testing for product bio-similarity. • Trained working in a cGMP environment; Generated technical reports, protocols, SOPs, and memos.

• Performed research on molecular modeling of nanoparticles and their behaviors in biological systems. • Published 3 peer-reviewed journal articles, 1 book chapter, and 5 national conference presentations. • Supported lab researchers and supervisors in generating grant (NSF, DOE, NIH, etc.) proposals. • Mentored junior students in the lab at undergraduate and graduate levels. • Member of the American Institute of Chemical Engineers (AIChE) and American Chemical Society (ACS).Selected Books, Publications, and Presentations: • Cynthia J. Jameson, Priyanka Oroskar, Bo Song, Huajun Yuan, Sohail Murad, Molecular Dynamics Studies of Nanoparticle Transport Through Model Lipid Membranes, Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization, Chapter 5 p. 109 – 165, Fatma N. (Editor), Springer, Heidelberg, 2019 • Bo Song, Huajun Yuan, Sydney V. Pham, Cynthia J. Jameson, Sohail Murad, Nanoparticle permeation induces water penetration, ion transport and lipid molecule flip-flop, Langmuir, 28, 16989-17000, 2012. • Bo Song, Huajun Yuan, Cynthia J. Jameson, Sohail Murad, Nanoparticle Permeation Induced Water Penetration and Ion Transport Through a Lipid Membrane, AIChE Annual Meeting, oral presentation, 2012 • Bo Song, Huajun Yuan, Cynthia J. Jameson, Sohail Murad, Role of surface ligands in nanoparticle permeationthrough a model membrane: A coarse-grained molecular dynamics simulations study, Molecular Physics 110, 2181-2195, 2012 • Bo Song, Huajun Yuan, Cynthia J. Jameson, Sohail Murad, Permeation of gold nanocrystals across lipid membranes, Molecular Physics 109, 1511-1526, 2011

• Built Circulating Fluidized Bed Boiler (CFB Boiler) Heat Efficiency prediction model. • Perform Built CFB Boiler Heat Efficiency process optimal control based on Artificial Neutral Network (ANN) methodologies and Genetic Algorithm (GA). • Dissertation: The Circulating Fluidized Bed Boiler Heat Efficiency Optimal Control Research, Bo Song, Zhikai Cao, Qingyin Jiang, Xiamen University, 2008