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• Passionate about the use of precision medicine to cure disease• Results oriented leader with strong technical background• Experienced in starting up and maintaining lab operations • Involved in business development with identifying strategic partners • Familiar with IP, patents, and FDA regulations for translating drug development to clinical trialsI can be contacted at brad@arizbio.com
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CeoAriz Precision Medicine Sep 2020 - PresentDavis, California, UsARIZ Precision Medicine is targeting cancer at the root cause, a genetic error that occurs early in the cancerization of humans. Our lead drug candidate is undergoing proof of concept studies in animal models of lung cancer. We have drug candidates for breast, colon, liver, lung, ovarian and prostate cancer that we will be testing over the next 12-18 months. We have several partnerships already and intend to add a strategic partner to license our cancer drug candidates. We were recently honored by several organizations for our efforts in the cancer field. -
Chief Operating OfficerAriz Precision Medicine Apr 2017 - Sep 2020Davis, California, Us• Supported and drove new innovation in product development• Identified and established agreements with strategic partners to drive technology development• Worked with CEO to identify and secure investments• Mentored a team of PhD students in the UC Davis Big Bang business competition
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Vice President Of R&DAriz Precision Medicine Jun 2016 - Sep 2020Davis, California, Us• Lab manager for new startup, started lab operations, identified and hired staff• Project leader for proof of concept experiments for development of pre-clinical drug candidates• Experienced with numerous in vitro and in vivo drug testing approaches• Inventor on multiple patent applications
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Senior ScientistAfingen, Inc Mar 2015 - May 2016Oakland, California, Us• Project leader for engineering yeast for production of high levels of multiple biofuel compounds• Achieved a high level of heterologous gene expression, monitored pathway intermediates by LC-MS and final products by GC-MS• Developed screen for identification of high copy DNA integrations in yeast.• Use of S. cerevisiae and oleaginous yeast -
Biologist Affiliate ScientistJoint Bioenergy Institute & Lawrence Berkeley National Lab Mar 2015 - May 2016 -
Assistant Project ScientistUc Davis Jan 2013 - Mar 2015Davis, California, Us• Performed microarray analysis to identify defect in reactive oxygen stress (ROS) response pathway involved in regulation of actin cytoskeletal architecture• Utilized genetic screening to identify novel feedback loop for regulation of sphingolipid metabolism• Re-engineering of metabolic signaling pathways to restore signaling defects• Lab managing, including training and managing of students -
Post-Doctoral ResearcherUc Davis Nov 2007 - Dec 2012Davis, California, Us• Designed and implemented experiments which identified novel form of kinase regulation that involved targeting through a protein-protein interaction• Identified multiple pro-growth kinase targets through in vitro and in vivo protein expression screens• Performed kinase active site genetic re-engineering to develop specific inhibition of kinases
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Ph.D. StudentUc Davis Sep 2000 - Jun 2007Davis, California, UsUtilized molecular biology techniques to identify mechanisms behind apoptosis resulting from a zinc deficiency. Specifically, I characterized zinc’s involvement in growth factor signaling pathways, as well as the molecular mechanisms behind iron accrual secondary to a zinc deficiency
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Intern, Designated Emphasis In Biotechnology ProgramMonsanto Jun 2006 - Dec 2006St. Louis, Missouri, Us -
InternDnax Research Institute Jul 2000 - Sep 2000Us -
InternDnax Research Institute Jun 1999 - Aug 1999Us
Brad Niles Skills
Brad Niles Education Details
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University Of California, DavisNutritional Biology With Designated Emphasis In Biotechnology -
Uc San DiegoPhysiology
Frequently Asked Questions about Brad Niles
What company does Brad Niles work for?
Brad Niles works for Ariz Precision Medicine
What is Brad Niles's role at the current company?
Brad Niles's current role is CEO at ARIZ Precision Medicine.
What is Brad Niles's email address?
Brad Niles's email address is bj****@****vis.edu
What schools did Brad Niles attend?
Brad Niles attended University Of California, Davis, Uc San Diego.
What skills is Brad Niles known for?
Brad Niles has skills like Molecular Biology, Western Blotting, Mammalian Cell Culture, Fluorescence Microscopy, Yeast Genetics, Sphingolipid Biology, Molecular Cloning, Cell Signaling, Biotechnology, Yeast, Rt Pcr, Protein Expression.
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