Brad Acker Email & Phone Number

Chesterfield, MO, US

Led a team of Business Analysts in the design, development and release of an in-house suite of applications used to manage and maintain Field Compliance for USDA, EPA and Product Stewardship trials. Designed and delivered best-in-industry compliance management system for use by field researches, academic collaborators and contract research organizations..

Worked on cross functional teams to design, develop and advance drug candidates for Cardiovascular (PDE5), Allergy & Respiratory and Inflammation (JAK) projects. Contributed to project successes through route optimization and multi gram synthesis of advanced intermediates. Given the “Green Chemistry Award” for identifying and implementing solutions for the.

Synthesis and route optimization of novel compounds for the treatment of schizophrenia. Instrumental in the discovery of PHA-709829 and other Alpha-7 nAChRs through discovery and chiral synthesis of (3R,5R)-1-azabicyclo[3.2.1]octane-3-amine.

Honed synthetic and analytical chemistry skills while preparing molecules indicated for HIV (peptidomimetics) and CNS (azapinoindole) disease areas. Developed and optimized the preclinical route to the PNU-142774 and worked closely with pharmaceutical sciences colleagues to identify the best of its pharmaceutically acceptable salts enabling clinical.