Lead Gilead’s bioconjugation process development with a focus on Antibody Drug Conjugates (ADCs)o Developed and implemented a novel ADC purification for removal of free drug related impurities (FDRI) – Patent in draftRedeveloped drug substance conjugation process for a commercial programo Utilized Quality by Design (QbD) principles and ICH guidelines to complete process characterization and design an updated control strategy for commercial programAuthored, reviewed and approved risk assessments (FMEA), process characterization protocols, control strategy, and process description to enable PPQo Write and review the relevant Chemistry, Manufacturing and Controls (CMC) sections of the BLALead development tech transfer to multiple CMOs for updated DS processo Review and approve master batch records (MBRs)o Help manage deviations through GVault Quality Management System (QMS)Manage 3 direct reportsImplemented a platform process to provide pre-clinical ADCs to research teams

Served as Purification and Drug Substance lead for two internal programs (mAb and ADC)o Supported successful tech transfer for downstream purification and conjugation for two clinical sitesBatch Record review, Person-in-plant for clinical manufacturingAuthored relevant CMC sections of the IND Designed and oversaw execution of successful viral clearance studies

Managed 7 direct reports across purification, analytical development, and peptide productiono Improved employee utilization rate from 50% to 80% over a 1-year time periodImplemented support committee to enable new program leadersPrepared board presentations on company timelines and program deliverables

Program lead for 4 programso Led the development of Avitide’s first licensed resino Oversee all aspects of development: ligand discovery, ligand production, resin conjugation, purification, and analyticsDeveloped and scaled up ligand purification to produce clinical scale resin batchesSpecialized in the development and optimization of purification process for gene therapies (AAV and lentivirus), exosomes, and difficult to purify bispecific antibodies

Developed high-throughput conjugation and screening for bespoke resinsSpearheaded campaign to lower cost to discover ligands by > 50%

Developed easy, cheap, and green purification technology with a goal to commercialize a research scale protein purification kit (currently raised >3.6 MM)

Position focused on developing functionalized carbon (graphene and carbon nanotubes) and silicon materials with proteins for use in biosensing, bioimaging and circuitry • Mentored 3 PhD and 2 Master’s students in design of experiments, statistics, fluorescence microscopy, FPLC, AFM and SPR• Implemented new purification technology used by several lab members to reduce protein purification times by over 85% • Conducted protein stability and aggregation analysis on complex systems• Invented micro-contact printing technique to print multiple enzymes onto silica and silicon substrates in an oriented and well-ordered fashion using a silica binding aptamer- Pursuing patent through University of Washington• Acted as an outside advisor for team that competed in the Alaska Airline Environmental Innovation Challenge using the my technology • Highlighted technical skills: protein engineering, protein purification, design of experiments, fluorescence spectrophotometry, mass spectrometry, differential scanning calorimetry, ultrafiltration/diafiltration (UFDF), capillary electrophoresis (CE and CZE) and protein analytics

Position focused on the development of inorganic binding proteins• Pioneered a cheap, disposable protein purification system (SiliCar9) that is over 15x cheaper than commonly used His-tag protein purification• Procured IP for SiliCar9 purification technology (patent filed)• Awarded Teaching Assistant of the year in 2010 through student vote• Investigated the development of robust and simple strategies to directly functionalize graphene, diamond and silicon based materials with proteins in aqueous solutions• Researched and wrote a book chapter for protein-aided mineralization of inorganic nanostructures• Spearheaded all equipment repairs and procurement• Implemented lab strategies to reduce congestion on equipment• Undertook lab rotation in Materials science and studied several diverse courses to procure a dual PhD in nanotechnology• Highlighted technical skills: Directed evolution and display technology (FliTrx and Phage display), AKTA chromatography (FPLC and HPLC), molecular biology, SDS-PAGE, Western-blots, purification technology (IEX, SEC, HIC, and affinity tag), circular dichroism, surface plasmon resonance (SPR), quartz crystal microbalance (QCM), fluorescence microscopy, Raman spectroscopy, UV-Vis spectroscopy, protein refolding, membrane protein expression, dynamic light scattering, ELISA, and atomic force microscopy

Hutchinson Technology is a world-class precision manufacturer of disk drive components. At the time of my employment, HTI reported over $700 million in revenue per year. I held an R&D position focused on improving in-house gold plating technologies• Instructed 1 direct report and 2 indirect reports • Developed trade secret plating technology for elimination of solder voids • Redesigned and replaced all plating equipment in the experimental lab • Highlighted technical skills: microscale metal plating (gold, nickel, and copper), photolithography, reel-to-reel processing, surface analysis (SEM, TEM, FIB, ESCA), sputtering, soldering, and plating equipment design

Studied the development of a polymer material that allowed for specific diffusion of water as an alternative material for HAZMAT suits• Helped design polymerization conditions for a novel diblock copolymer